Results 211 to 220 of about 1,828,854 (335)

A Non‐Covalent [4Fe–4S]/[2Fe] Interface in HydF Guides [FeFe]‐Hydrogenase Maturation

Angewandte Chemie, EarlyView.
Bridged or not? 57Fe NRVS reveals a non‐covalent, electronically coupled interaction between the HydF [4Fe–4S] cluster and the [2Fe] precursor. Boltz‐2 structure predictions suggest that the cubane organizes lipoate‐dependent Hmet chemistry, positioning intermediates for assembly of the CH2–NH–CH2 bridge during H‐cluster biosynthesis.
Giorgio Caserta, Princess R. Cabotaje, Armel T. Waffo, Deepak Prajapat, Ilya Sergueev, Stefan Frielingsdorf, Gustav Berggren   +6 more
wiley   +2 more sources

Hydrogen Sulfide Metabolism in the Skin: From Physiology to Malignancy. [PDF]

Int J Mol Sci
Tampa M, Nicolae I, Mitran MI, Mitran CI, Matei C, Georgescu SR, Capusa C, Ene CD.   +7 more
europepmc   +1 more source

Chemically Regulated STING‐Activating Prodrugs of Deoxyribose Cyclic Dinucleotides Elicit Robust Immune Activation and Durable Antitumor Immunity

Angewandte Chemie, EarlyView.
All three diastereoisomers of an esterase‐sensitive phosphotriester dCDN prodrug demonstrate improved activity. The (Rp,Rp) diastereoisomer shows the highest activity with an EC50 of 1.7 nM in STING activation and displays the most pronounced antitumor activity via intravenous administration, significantly suppressing tumor proliferation, extending the
Zhiqiang Xie, Huimin Liu, Yuchen Yang, Xiaohan Sun, Jingwen Wang, Tianxiang Liu, Baifan Wang, Wenrui Qiu, Yiwen Sun, Yuting Bai, Yao Zhang, Dejun Ma, Rong Xiang, Shibo Li, Zhen Xi   +14 more
wiley   +2 more sources

Involvement of cystathionine β-synthase in ATP-induced hydrogen sulfide production in cochlear outer hair cells. [PDF]

J Otol
Harada N, Ito Y, Takashima I, Ojida A, Sekiguchi F, Kawabata A.   +5 more
europepmc   +1 more source

Phosphoryl Radicals from Trivalent Iminyl Phosphines: A Photocatalytic Approach to N‐Phosphoryl Azetidines

Angewandte Chemie, EarlyView.
Photochemically generated phosphoryl radicals from iminyl phosphines enable strain‐release addition to azabicyclobutanes, providing access to elusive N‐phosphoryl azetidines. Combined experimental, computational, and EPR studies reveal an unconventional water‐assisted photoredox pathway.
Chandu G. Krishnan, Gabriel Cormier, Stefano A. Serapian, Marco Bortolus, Luca Dell'Amico   +4 more
wiley   +2 more sources

Bioelectronic synthesis of hydrogen sulfide enables spatiotemporal regulation of protein modification and cellular redox. [PDF]

Sci Adv
Lim L, Lee C, Lee J, Lee M, Kim Y, Lee TK, Lee G, Kim J, Oh SY, Kim J, Park J.   +10 more
europepmc   +1 more source

Embracing sulfide and CO to understand nitric oxide biology

Feelisch, Martin, Olson, Kenneth R.
core   +1 more source

Decreased Plasma Concentration of Hydrogen Sulfide in Hospitalized COVID-19 Patients: A Novel Determinant of Mortality? [PDF]

Antioxidants (Basel)
Stranieri C, Di Leo EG, Danese E, Poffe R, Barbieri A, Pighi L, Randon A, Cominacini L, Fratta Pasini AM.   +8 more
europepmc   +1 more source

Role of hydrogen sulfide in catalyzing the formation of NO-ferroheme. [PDF]

Nitric Oxide
Poudel L, Karunarathna T, Baker S, Alipour E, Dent MR, Tejero J, Gladwin MT, DeMartino AW, Kim-Shapiro DB.   +8 more
europepmc   +1 more source

Correction to "Development of a Simple New Method to Detect Oral Malodor Using a Hydrogen Sulfide Detector Tube". [PDF]

Int J Dent
europepmc   +1 more source