Results 181 to 190 of about 297,801 (378)

The P134Q Sucrose Phosphorylase: Subtle Changes in the Catalytic Properties Benefit the Production of 2‐O‐α‐Glucosyl Glycerol

open access: yesBiotechnology and Bioengineering, EarlyView.
Production of the cosmetic ingredient 2‐α‐d‐glucosyl glycerol (2GG) by the Pro134Gln variant of sucrose phosphorylase from Bifidobacterium adolescentis is reported. The authors show with detailed characterization and hybrid kinetic modeling that the enzyme variant can improve the 2GG productivity of the biocatalytic process due to its increased ...
Alexander Sigg   +5 more
wiley   +1 more source

An Adenosine Hydrolase from Brussels Sprouts

open access: hybrid, 1963
Mendel Mazelis, Richard K. Creveling
openalex   +1 more source

Engineering antibodies with cancer‐associated binding sites

open access: yesBMEMat, EarlyView.
This review describes antibodies that perform direct/indirect roles in cancer treatment by binding to effective targets and discusses how antibodies kill tumors and modulate tumor microenvironment through these targets. The classification of expression systems for antibody production is summarized to guide appropriate selection based on different ...
Yinqi Tian   +4 more
wiley   +1 more source

Artificial intelligence‐assisted design, synthesis and analysis of smart biomaterials

open access: yesBMEMat, EarlyView.
Smart biomaterials are rapidly emerging as tools for tissue engineering, and artificial intelligence has played essential roles in biomaterial studies. By bridging the literature gap in AI‐based design, synthesis and analysis of smart biomaterials, the current review shares perspectives on how biomaterial scientists can practically incorporate AI for ...
Pengfei Jiang   +9 more
wiley   +1 more source

Ubiquitination in cancer: mechanisms and therapeutic opportunities

open access: yesCancer Communications, EarlyView.
Abstract Ubiquitination, a key post‐translational modification, plays an essential role in tumor biology by regulating fundamental cellular processes, such as metabolism and cell death. Additionally, it interacts with other post‐translational modifications, which are closely linked to tumorigenesis, tumor progression, the tumor microenvironment, and ...
Susi Zhu   +7 more
wiley   +1 more source

Pharmacokinetic Prediction and Cytotoxicity of New Quercetin Derivatives

open access: yesChemistry &Biodiversity, EarlyView.
ABSTRACT Quercetin (QUE) possesses various pharmacological properties; however, its low bioavailability and solubility hinder its beneficial effects. Enzymatic glycosylation has been explored to improve these aspects. In the present study, we used a sucrose phosphorylase variant to catalyze the regioselective transglucosylation of QUE, predicted the ...
Michele Goulart dos Santos   +8 more
wiley   +1 more source

Localization of Acid Hydrolases in Protoplasts [PDF]

open access: bronze, 1977
Henry C. Butcher   +2 more
openalex   +1 more source

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