Results 191 to 200 of about 297,801 (378)
B. Cravatt+6 more
semanticscholar +1 more source
Multimodular carbohydrate‐active enzymes often combine different catalytic activities for efficient polysaccharide degradation. In this work, the structural and functional characterization of three multimodular xylan‐targeting esterases, Fl6, Fll1 and Fll4 from Flavimarina sp. Hel_I_48, are presented.
Michelle Teune+4 more
wiley +1 more source
Cellular cholesteryl ester metabolism is regulated largely by the balance between intracellular esterification catalyzed by acyl-CoA:cholesterol acyltransferase and cholesteryl ester hydrolysis catalyzed by the cholesteryl ester hydrolases.
S.K Erickson, S.R Lear, M.J McCreery
doaj
Glycyl-
Manjusri Das, A.N. Radhakrishnan
openalex +1 more source
Inhibition of soluble epoxide hydrolase prevents diabetic retinopathy
Jiong Hu+21 more
semanticscholar +1 more source
This study describes the successful identification of ancestral sequences N50 and N49, which have a longer half‐life of approximately four and two times the wild‐type Sp‐amine transaminase, respectively.. This approach effectively enhances the thermal stability of the transaminase.
Luyao Zhao+4 more
wiley +1 more source
Acetyl‐CoA Hydrolase; Activity, Regulation and Physiological, Significance of the Enzyme in Brown Adipose Tissue from Hamster [PDF]
Vibeke Bernson
openalex +1 more source
Diversity of ThDP‐Dependent Enzymes Forming Chiral Tertiary Alcohols
Chiral tertiary alcohols are widespread in nature and bioactive compounds; however, their asymmetric synthesis faces several challenges. This review outlines the toolbox of ThDP‐dependent enzymes able to produce tertiary alcohols through the formation of CC bond formation using ketones as acceptor substrates. Herein, the substrate scope, the diversity
Daniela Bjarnesen+4 more
wiley +1 more source
Cholesteryl ester (CE) accumulation in macrophages represents a crucial event during foam cell formation, a hallmark of atherogenesis. Here we investigated the role of two previously described CE hydrolases, hormone-sensitive lipase (HSL) and KIAA1363 ...
Marlene Buchebner+18 more
doaj