Results 91 to 100 of about 7,064 (119)
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DNA hydrogels and nanogels for diagnostics, therapeutics, and theragnostics of various cancers.

Nanoscale, 2023
As an efficient class of hydrogel-based therapeutic drug delivery systems, deoxyribonucleic acid (DNA) hydrogels (particularly DNA nanogels) have attracted massive attention in the last five years.
Iman Zare   +6 more
semanticscholar   +1 more source

Hydrophilic Fluorescent Nanogel Thermometer for Intracellular Thermometry

Journal of the American Chemical Society, 2009
The first methodology to measure intracellular temperature is described. A highly hydrophilic fluorescent nanogel thermometer developed for this purpose stays in the cytoplasm and emits stronger fluorescence at a higher temperature. Thus, intracellular temperature variations associated with biological processes can be monitored by this novel ...
Chie, Gota   +4 more
openaire   +2 more sources

How Softness Matters in Soft Nanogels and Nanogel Assemblies.

Chemical Reviews, 2022
Softness plays a key role in determining the macroscopic properties of colloidal systems, from synthetic nanogels to biological macromolecules, from viruses to star polymers.
A. Scotti   +5 more
semanticscholar   +1 more source

Hydrophilicity/Hydrophobicity Reversable and Redox-Sensitive Nanogels for Anticancer Drug Delivery

Molecular Pharmaceutics, 2015
Long circulation in the blood, efficient cellular internalization, and intracellular drug release in the tumor cells are major challenges in the development of ideal anticancer drug delivery systems. In this paper, hydrophilicity/hydrophobicity reversable and redox-sensitive poly(oligo(ethylene glycol) methacrylates-ss-acrylic acid) (P(OEGMAs-ss-AA ...
Hao, Yang   +7 more
openaire   +2 more sources

Bioengineered nanogels for cancer immunotherapy.

Chemical Society Reviews, 2022
Recent years have witnessed increasingly rapid advances in nanocarrier-based biomedicine aimed at improving treatment paradigms for cancer. Nanogels serve as multipurpose and constructed vectors formed via intramolecular cross-linking to generate drug ...
Xianbin Ma   +7 more
semanticscholar   +1 more source

Fabrication and Characterization of Thymol‐Loaded Chitosan Nanogels: Improved Antibacterial and Anti‐Biofilm Activities with Negligible Cytotoxicity

Chemistry and Biodiversity, 2022
Thymol is a monoterpene phenolic derivative extracted from the Thymus vulgaris which has antimicrobial effects. In the present study, thymol‐loaded chitosan nanogels were prepared and their physicochemical properties were characterized. The encapsulation
Tohid Piri-Gharaghie   +10 more
semanticscholar   +1 more source

Selective Release of Hydrophobic and Hydrophilic Cargos from Multi-Stimuli-Responsive Nanogels

ACS Applied Materials & Interfaces, 2016
Highly stable multi-stimuli-responsive nanogels for selective release of simultaneously encapsulated hydrophobic and hydrophilic cargos in a spatiotemporally controlled manner are demonstrated here. The nanogel is composed of hydrophilic pH- and thermoresponsive poly(2-(dimethylamino)ethyl methacrylate) (PDMAEMA) and hydrophobic photocleavable o ...
Ziquan, Cao   +2 more
openaire   +2 more sources

Design of hydrophilic photocleavage o-nitrobenzyl acrylate-modified nanogels with outstanding biocompatibility prepared by RAFT polymerization for drug carrier

European Polymer Journal, 2020
Abstract Three kinds of hydrophilic photocleavage o-nitrobenzyl acrylate-modified nanogels with different particle size and narrow particle size distribution (1.8–0.24) were designed and synthesized by reversible addition-fragmentation chain transfer radical (RAFT) polymerization based on methoxy polyethylene glycol methacrylate (MPEGMA) and UV-light
Fuhua Xin   +6 more
openaire   +1 more source

Microgels and Nanogels for the Delivery of Poorly Water-Soluble Drugs.

Molecular Pharmaceutics, 2022
While microgels and nanogels are most commonly used for the delivery of hydrophilic therapeutics, the water-swollen structure, size, deformability, colloidal stability, functionality, and physicochemical tunability of microgels can also offer benefits ...
Ridhdhi Dave   +4 more
semanticscholar   +1 more source

Covalent-bonded immobilization of enzyme on hydrophilic polymer covering magnetic nanogels

Microporous and Mesoporous Materials, 2008
Abstract A new mesoporous support, hydrophilic polymer covering magnetic nanogels containing reactive carboxyl groups, was obtained by photochemical in situ polymerization. The enzyme α-chymotrypsin (CT), a model for protein or esters hydrolysis, was anchored to the support by 1-ethyl-3-(3-dimethylaminepropyl) carbodiimide (EDC) activation.
Jun Hong   +5 more
openaire   +1 more source

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