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Recent Advances in Ophthalmic Drug Delivery [PDF]
Pharmaceutics, 2022 Due to population aging and to the increasing prevalence of diseases such as diabetes, chronic eye disorders such as glaucoma, age-related macular degeneration, and diabetic retinopathy have increased significantly, becoming responsible for a high ...
Anuj Chauhan +2 more
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Gel-Based Materials for Ophthalmic Drug Delivery [PDF]
Gels, 2021 The most common route of administration of ophthalmic drugs is the topical route because it is convenient, non-invasive, and accessible to all patients. Unfortunately, drugs administered topically are not able to reach effective concentrations. Moreover,
Roberta Cassano +2 more
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Ophthalmic Drug Delivery in Glaucoma—A Review [PDF]
Pharmaceutics, 2012 Glaucoma is a progressive optic neuropathy and medical therapy is the initial option for the treatment of this potentially blinding condition. Topical instillation of eye drops from the bottle is the most common glaucoma drug delivery form.
Ingrida Januleviciene +2 more
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Advances in Ophthalmic Drug Delivery [PDF]
Therapeutic Delivery, 2014 Various strategies for ocular drug delivery are considered; from basic formulation techniques for improving availability of drugs; viscosity enhancers and mucoadhesives aid drug retention and penetration enhancers promote drug transport into the eye. The use of drug-loaded contact lenses and ocular inserts allows drugs to be better placed where they ...
Morrison, Peter W. J. +1 more
core +7 more sources
New ophthalmic drug delivery systems [PDF]
Farmacia Hospitalaria, 2020 For decades, topical ophthalmic drug administration through the use of eye drops has been the most widely used technique for the treatment of eye diseases.
Ana Castro-Balado +3 more
doaj +4 more sources
Emulsion and Emulgel-Based Ophthalmic Drug Delivery Systems [PDF]
PharmaceuticsOphthalmic drug delivery encounters unique challenges due to the anatomical and physiological ocular barriers, necessitating the development of novel drug delivery systems (NDDSs).
Debadatta Mohapatra +2 more
doaj +2 more sources
Ophthalmic Drug Delivery Systems (Review)
Разработка и регистрация лекарственных средств, 2021 Introduction. Effective delivery of ophthalmic drugs is challenging. The eye has a number of protective systems and physiological barriers, which is why ophthalmic dosage forms have a low bioavailability, usually not exceeding 5 %.
E. O. Bakhrushina +5 more
doaj +3 more sources
Perspective use of bio-adhesive liquid crystals as ophthalmic drug delivery systems [PDF]
Scientific Reports, 2023 The success of many drugs in ophthalmic treatments is hindered by their physico-chemical properties and the limited precorneal retention time. Here, lyotropic liquid crystals are proposed as a new ophthalmic drug delivery system.
Martine Tarsitano +6 more
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Ophthalmic Drug Delivery Systems for Antibiotherapy—A Review [PDF]
Pharmaceutics, 2018 The last fifty years, ophthalmic drug delivery research has made much progress, challenging scientists about the advantages and limitations of this drug delivery approach.
Marion Dubald +3 more
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Nanostructure-based platforms-current prospective in ophthalmic drug delivery
Indian Journal of Ophthalmology, 2014 The topically applied drugs as drops are washed off from the eye in very short period, resulting in low ocular bioavailability of drugs. Number of approaches have been attempted to increase the bioavailability and the duration of action of ocular drugs ...
Rakesh Kumar Sharma +1 more
doaj +2 more sources