Results 11 to 20 of about 3,065,508 (250)
New ophthalmic drug delivery systems [PDF]
Farmacia Hospitalaria, 2020 For decades, topical ophthalmic drug administration through the use of eye drops has been the most widely used technique for the treatment of eye diseases.
Ana Castro-Balado +3 more
doaj +5 more sources
Diffusion-Based Design of Multi-Layered Ophthalmic Lenses for Controlled Drug Release. [PDF]
PLoS ONE, 2016 The study of ocular drug delivery systems has been one of the most covered topics in drug delivery research. One potential drug carrier solution is the use of materials that are already commercially available in ophthalmic lenses for the correction of ...
Andreia F R Pimenta +5 more
doaj +3 more sources
PharmaceuticsEye disorders affect a substantial portion of the global population, yet the availability of efficacious ophthalmic drug products remains limited. This can be partly ascribed to a number of factors: (1) inadequate understanding of physiological barriers,
Bhupendra Raj Giri +4 more
doaj +2 more sources
Punctal and Intracanalicular Drug Delivery Systems for Ophthalmic Use: A Narrative Review of Technologies, Clinical Outcomes, and Critical Quality Attributes [PDF]
PharmaceuticsBackground: Conventional ophthalmic eye drops have low bioavailability (80% over 4 weeks), swelling degree (30–60%), controlled burst release (
Elena O. Bakhrushina +9 more
doaj +2 more sources
Ophthalmic Sensors and Drug Delivery [PDF]
ACS Sensors, 2021 Advances in multifunctional materials and technologies have allowed contact lenses to serve as wearable devices for continuous monitoring of physiological parameters and delivering drugs for ocular diseases. Since the tear fluids comprise a library of biomarkers, direct measurement of different parameters such as concentration of glucose, urea ...
Antonysamy Dennyson Savariraj +7 more
openaire +3 more sources
Nanomedicine-Based Ophthalmic Drug Delivery Systems for the Treatment of Ocular Diseases. [PDF]
Int J NanomedicineLin X, Zhou Y, Lv K, Wu W, Chen C.
europepmc +2 more sources
Advances in Ophthalmic Drug Delivery [PDF]
Therapeutic Delivery, 2014 Various strategies for ocular drug delivery are considered; from basic formulation techniques for improving availability of drugs; viscosity enhancers and mucoadhesives aid drug retention and penetration enhancers promote drug transport into the eye. The use of drug-loaded contact lenses and ocular inserts allows drugs to be better placed where they ...
Morrison, Peter W. J. +1 more
openaire +3 more sources
A review on nanotechnology based ophthalmic drug delivery system [PDF]
, 2023 The field of ophthalmic drug delivery has witnessed significant advancements through the integration of nanotechnology. Despite having numerous conventional dosage forms employed in the ocular drug delivery system the problem of less bioavailability and ...
Monde, Ashish Ashok +5 more
core +1 more source
Ophthalmic Drug Delivery Systems (Review)
Разработка и регистрация лекарственных средств, 2021 Introduction. Effective delivery of ophthalmic drugs is challenging. The eye has a number of protective systems and physiological barriers, which is why ophthalmic dosage forms have a low bioavailability, usually not exceeding 5 %.
E. O. Bakhrushina +5 more
doaj +1 more source
Mucoadhesive micelles for ophthalmic drug delivery. [PDF]
J Biomater ApplThe most common formulation for treating ocular conditions is topical eyedrops, despite their well-documented inefficiency. In this study, mucoadhesive nano-micelles were developed to overcome the poor efficacy of topical eyedrops in the treatment of dry eye disease.
Goostrey T +4 more
europepmc +3 more sources