Results 21 to 30 of about 3,065,508 (250)

Nanofibers as a drug carrier in ophthalmic therapy [PDF]

Farmacja Polska, 2021
In ophthalmic therapy, drugs of various structures are used, administered into the conjunctival sac or onto the cornea. Novel concepts of technological development of the form of an ophthalmic drug delivery systems include obtaining a higher ...
Anna Czech, Ewelina Łyszczarz, Renata Jachowicz   +2 more
doaj   +1 more source

An Integrated Theranostic Nanomaterial for Targeted Photodynamic Therapy of Infectious Endophthalmitis

Cell Reports Physical Science, 2020
Summary: Infectious endophthalmitis is a growing concern that causes irreversible intraocular tissue and optic nerve damage. Here, we report a theranostic nanoplatform based on UiO-66-NH2 to combine photodynamic therapy (PDT) and lipopolysaccharide (LPS)
Yingying Jin, Yuqin Wang, Jie Yang, Hengrui Zhang, Ying-Wei Yang, Wei Chen, Wenya Jiang, Jia Qu, Yishun Guo, Bailiang Wang   +9 more
doaj   +1 more source

In Situ Gelling Ophthalmic Drug Delivery System for the Optimization of Diagnostic and Preoperative Mydriasis: In Vitro Drug Release, Cytotoxicity and Mydriasis Pharmacodynamics. [PDF]

Pharmaceutics, 2020
Mydriasis is required prior to many eye examinations and ophthalmic surgeries. Nowadays, phenylephrine hydrochloride (PHE) and tropicamide (TPC) are extensively used to induce mydriasis.
Destruel PL, Zeng N, Brignole-Baudouin F, Douat S, Seguin J, Olivier E, Dutot M, Rat P, Dufaÿ S, Dufaÿ-Wojcicki A, Maury M, Mignet N, Boudy V.   +12 more
europepmc   +2 more sources

A Review on Conventional and Novel Topical Ocular Drug Delivery System

Journal of Pharmacy, 2021
Ocular drug delivery is a very challenging area for ophthalmologists and drug delivery scientists due to the structural and barrier complexity of the eye.
Mohamad Faeznudin Rozi, Awis Sukarni Mohmad Sabere   +1 more
doaj   +1 more source

Dendrimer and dendrimer gel‐derived drug delivery systems: Breaking bottlenecks of topical administration of glaucoma medications

MedComm – Biomaterials and Applications, 2023
Due to high structural flexibility, multidrug carrying capability, and tunable size, dendrimers have been used as suitable carriers for ophthalmic drug delivery. Drug molecules can be either encapsulated or chemically coupled to dendrimers.
Juan Wang, Boxuan Li, Uday B. Kompella, Hu Yang   +3 more
doaj   +1 more source

Nanoparticles in ocular applications and their potential toxicity

Frontiers in Molecular Biosciences, 2022
Nanotechnology has been developed rapidly in recent decades and widely applied in ocular disease therapy. Nano-drug delivery systems overcome the bottlenecks of current ophthalmic drug delivery and are characterized with strong biocompatibility ...
Cao Yang, Cao Yang, Junling Yang, Junling Yang, Ao Lu, Ao Lu, Jing Gong, Yuanxing Yang, Yuanxing Yang, Xi Lin, Xi Lin, Minghui Li, Minghui Li, Haiwei Xu, Haiwei Xu   +14 more
doaj   +1 more source

Research progress of ophthalmic preparations of immunosuppressants

Drug Delivery, 2023
Immune ophthalmopathy is a collection of autoimmune eye diseases. Immunosuppressants are drugs that can inhibit the body’s immune response. Considering drug side effects such as hepatorenal toxicity and the unique structure of the eye, incorporating ...
Ye Liu, Haonan Xu, Na Yan, Zhan Tang, Qiao Wang   +4 more
doaj   +1 more source

Release of functional dexamethasone by intracellular enzymes: A modular peptide-based strategy for ocular drug delivery [PDF]

, 2020
Tissue barriers limit drug delivery in the eye. Therefore, retinal diseases are treated with intravitreal injections. Delivery systems with reduced dosing frequency and/or cellular drug delivery properties are needed.
Sadeghi, Amir, Sarkhel, Sanjay, Bahrpeyma, Sina, Toropainen, Elisa, Auriola, Seppo, Bhattacharya, Madhushree, Hagström, Marja, Urtti, Arto   +7 more
core   +1 more source

Design of ophthalmic micelles loaded with diclofenac sodium: effect of chitosan and temperature on the block-copolymer micellization behaviour

, 2021
Diclofenac sodium 0.1% is a commonly used NSAID with well-documented clinical efficacy in reducing postoperative inflammation; however, its corneal tolerability and ophthalmic tissue bioavailability require further improvement. Advanced micellar delivery
Zoukh, Ikram Mustapha, Geskovski, Nikola, Goracinova, Katerina, Koummich, Sarra Aicha, Dodov, Marija Glavas, Gorachinov, Filip, Makreski, Petre, Marija Glavas Dodov, Nikola Geskovski, Ikram Mustapha Zoukh, Sarra Aicha Koummich, Katerina Goracinova, Petre Makreski, Filip Gorachinov   +13 more
core   +1 more source

Niosomes: A Novel Carrier Drug Delivery System [PDF]

, 2021
Niosomes are a novel drug delivery system, in which the medication is encapsulated in a vesicle. The vesicle is composed of a bilayer of non-ionic surfactants.
Shinde, Jitendra V, Chavan, Rajashree S, Borawake, Payal D, Kauslya, Arumugam, Arumugam Kauslya, Rajashree S Chavan, Payal D Borawake, Jitendra V Shinde   +7 more
core   +1 more source