Results 21 to 30 of about 16,351 (146)

An Integrated Theranostic Nanomaterial for Targeted Photodynamic Therapy of Infectious Endophthalmitis

open access: yesCell Reports Physical Science, 2020
Summary: Infectious endophthalmitis is a growing concern that causes irreversible intraocular tissue and optic nerve damage. Here, we report a theranostic nanoplatform based on UiO-66-NH2 to combine photodynamic therapy (PDT) and lipopolysaccharide (LPS)
Yingying Jin   +9 more
doaj   +1 more source

Diffusion-Based Design of Multi-Layered Ophthalmic Lenses for Controlled Drug Release. [PDF]

open access: yesPLoS ONE, 2016
The study of ocular drug delivery systems has been one of the most covered topics in drug delivery research. One potential drug carrier solution is the use of materials that are already commercially available in ophthalmic lenses for the correction of ...
Andreia F R Pimenta   +5 more
doaj   +1 more source

A Review on Conventional and Novel Topical Ocular Drug Delivery System

open access: yesJournal of Pharmacy, 2021
Ocular drug delivery is a very challenging area for ophthalmologists and drug delivery scientists due to the structural and barrier complexity of the eye.
Mohamad Faeznudin Rozi   +1 more
doaj   +1 more source

Dendrimer and dendrimer gel‐derived drug delivery systems: Breaking bottlenecks of topical administration of glaucoma medications

open access: yesMedComm – Biomaterials and Applications, 2023
Due to high structural flexibility, multidrug carrying capability, and tunable size, dendrimers have been used as suitable carriers for ophthalmic drug delivery. Drug molecules can be either encapsulated or chemically coupled to dendrimers.
Juan Wang   +3 more
doaj   +1 more source

Nanoparticles in ocular applications and their potential toxicity

open access: yesFrontiers in Molecular Biosciences, 2022
Nanotechnology has been developed rapidly in recent decades and widely applied in ocular disease therapy. Nano-drug delivery systems overcome the bottlenecks of current ophthalmic drug delivery and are characterized with strong biocompatibility ...
Cao Yang   +14 more
doaj   +1 more source

Research progress of ophthalmic preparations of immunosuppressants

open access: yesDrug Delivery, 2023
Immune ophthalmopathy is a collection of autoimmune eye diseases. Immunosuppressants are drugs that can inhibit the body’s immune response. Considering drug side effects such as hepatorenal toxicity and the unique structure of the eye, incorporating ...
Ye Liu   +4 more
doaj   +1 more source

Ocular Drug Delivery Role of Contact Lenses

open access: yesDelhi Journal of Ophthalmology, 2015
Significant advances have been made in order to optimize drug delivery to ocular tissues. There has been considerable interest in the potential application of contact lenses for ocular drug delivery.
Anubhav Chauhan
doaj   +1 more source

A novel approach to achieve semi-sustained drug delivery to the eye through asymmetric loading of soft contact lenses

open access: yesHeliyon, 2023
Soft contact lenses are increasingly being explored as a vehicle for controlled delivery of ophthalmic drugs. However, traditional methods of drug-loading by soaking have limitations such as burst delivery and the release of drugs at the front side of ...
Malake Sarmout   +4 more
doaj   +1 more source

Nanotechnology-based ocular drug delivery systems: recent advances and future prospects

open access: yesJournal of Nanobiotechnology, 2023
Ocular drug delivery has constantly challenged ophthalmologists and drug delivery scientists due to various anatomical and physiological barriers. Static and dynamic ocular barriers prevent the entry of exogenous substances and impede therapeutic agents'
Shiding Li, Liangbo Chen, Yao Fu
doaj   +1 more source

Ophthalmic Drug Delivery Systems : An Update

open access: yesDelhi Journal of Ophthalmology, 2011
Drugs developed and approved for systemic disease are reinvestigated for ocular disease. However, developing new drugs with good intraocular penetration by considering the anatomical and physiological constraints exerted by the various barriers of eye is
Nihar Ranjan Biswas
doaj   +1 more source

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