Results 31 to 40 of about 16,351 (146)
Carbon Dots Fabrication: Ocular Imaging and Therapeutic Potential
Frontiers in Bioengineering and Biotechnology, 2020 Vision loss is a major complication in common ocular infections and diseases such as bacterial keratitis, age-related macular degeneration (AMD) and diabetic retinopathy (DR).
Inyoung Garner +11 more
doaj +1 more source
Lipid-Based Nanocarriers as Topical Drug Delivery Systems for Intraocular Diseases
Pharmaceutics, 2021 Effective drug delivery to intraocular tissues remains a great challenge due to complex anatomical and physiological barriers that selectively limit the entry of drugs into the eye.
Jose Navarro-Partida +5 more
doaj +1 more source
Recent Advances in Ophthalmic Drug Delivery [PDF]
Therapeutic Delivery, 2010 Topical ocular drug bioavailability is notoriously poor, in the order of 5% or less. This is a consequence of effective multiple barriers to drug entry, comprising nasolacrimal drainage, epithelial drug transport barriers and clearance from the vasculature in the conjunctiva.
Uday B, Kompella +2 more
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Improvements in Topical Ocular Drug Delivery Systems: Hydrogels and Contact Lenses
Journal of Pharmacy & Pharmaceutical Sciences, 2015 Conventional ophthalmic systems present very low corneal systemic bioavailability due to the nasolacrimal drainage and the difficulty to deliver the drug in the posterior segment of ocular tissue.
Andreza Maria Ribeiro +2 more
doaj +1 more source
Moxifloxacin releasing intraocular implant based on a cross-linked hyaluronic acid membrane
Scientific Reports, 2021 Intraocular antibiotic delivery is an important technique to prevent bacterial infection after ophthalmic surgery, such as cataract surgery. Conventional drug delivery methods, such as antibiotic eye drops, have limitations for intraocular drug delivery ...
Dong Ju Kim +6 more
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DNA nanoparticles for ophthalmic drug delivery [PDF]
Biomaterials, 2018 Nucleic acids represent very appealing building blocks for the construction of nano-scaled objects with great potential applications in the field of drug delivery where multifunctional nanoparticles (NPs) play a pivotal role. One opportunity for DNA nanotechnology lies in the treatment of ophthalmic diseases as the efficacy of eye drops is impaired by ...
de Vries, Jan Willem +8 more
openaire +3 more sources
Contact lenses for ophthalmic drug delivery [PDF]
Clinical and Experimental Optometry, 2017 Contact lenses as a means to deliver pharmaceuticals to the eye have seen a significant increase in research interest in the past few years. This review will detail the in vitro experiments which have investigated use of these contact lenses in the context of the desired pharmacological treatment goals in the management of infectious, inflammatory ...
openaire +2 more sources
Next-generation nanomaterials: advancing ocular anti-inflammatory drug therapy
Journal of Nanobiotechnology, 2023 Ophthalmic inflammatory diseases, including conjunctivitis, keratitis, uveitis, scleritis, and related conditions, pose considerable challenges to effective management and treatment.
Jing Wei +5 more
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Nanoparticles laden in situ gelling system for ocular drug targeting
Journal of Advanced Pharmaceutical Technology & Research, 2013 Designing an ophthalmic drug delivery system is one of the most difficult challenges for the researchers. The anatomy and physiology of eye create barriers like blinking which leads to the poor retention time and penetration of drug moiety.
Divya Kumar +3 more
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Dendrimeric Systems and Their Applications in Ocular Drug Delivery
The Scientific World Journal, 2013 Ophthalmic drug delivery is one of the most attractive and challenging research area for pharmaceutical scientists and ophthalmologists. Absorption of an ophthalmic drug in conventional dosage forms is seriously limited by physiological conditions.
Burçin Yavuz +2 more
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