Results 41 to 50 of about 16,351 (146)

Nanopharmaceuticals for Eye Administration: Sterilization, Depyrogenation and Clinical Applications

open access: yesBiology, 2020
As an immune-privileged target organ, the eyes have important superficial and internal barriers, protecting them from physical and chemical damage from exogenous and/or endogenous origins that would cause injury to visual acuity or even vision loss ...
Aleksandra Zielińska   +12 more
doaj   +1 more source

Applications of polymers in intraocular drug delivery systems

open access: yesOman Journal of Ophthalmology, 2017
We are entering a new era of ophthalmic pharmacology where new drugs are rapidly being developed for the treatment of anterior and posterior segment of the eye disease.
Ali Mohammed Alhalafi
doaj   +1 more source

Ocular administration of acetazolamide microsponges in situ gel formulations

open access: yesSaudi Pharmaceutical Journal, 2018
In the present work, the antiglaucoma drug, acetazolamide, was formulated as microsponges in situ gel for ocular drug delivery aiming an improved therapeutic efficacy and reduction in the systemic side effects of oral acetazolamide. The microsponges were
Manar M. Obiedallah   +2 more
doaj   +1 more source

Drug delivery strategies to improve the treatment of corneal disorders

open access: yesHeliyon
Anterior eye disorders including dry eye syndrome, keratitis, chemical burns, and trauma have varying prevalence rates in the world. Classical dosage forms based-topical ophthalmic drugs are popular treatments for managing corneal diseases.
Mahsa Fallah Tafti   +4 more
doaj   +1 more source

A Potential Application of a Piezoelectric Atomiser for Ophthalmic Drug Delivery

open access: yesApplied Bionics and Biomechanics, 2007
A liquid atomiser composed of a piezoelectric transducer and a metal plate with numerous micro-apertures is studied to identify the most influential factors on its atomising performance.
Wei Xia   +4 more
doaj   +1 more source

Contact lenses as drug controlled release systems: a narrative review

open access: yesRevista Brasileira de Oftalmologia, 2016
Topically applied therapy is the most common way to treat ocular diseases, however given the anatomical and physiological constraints of the eye, frequent dosing is required with possible repercussions in terms of patient compliance.
Helena Prior Filipe   +5 more
doaj   +1 more source

Ophthalmic Drug Dosage Forms: Characterisation and Research Methods

open access: yesThe Scientific World Journal, 2014
This paper describes hitherto developed drug forms for topical ocular administration, that is, eye drops, ointments, in situ gels, inserts, multicompartment drug delivery systems, and ophthalmic drug forms with bioadhesive properties.
Przemysław Baranowski   +3 more
doaj   +1 more source

Topical Ocular Drug Delivery: The Impact of Permeation Enhancers

open access: yesPharmaceutics
Topical ophthalmic drug delivery targeting the posterior segment of the eye has become a key area of interest due to its non-invasive nature, safety, ease of application, patient compliance, and cost-effectiveness.
Gonçalo Santos   +4 more
doaj   +1 more source

The Role of Xenobiotic Transporters in Ophthalmic Drug Delivery

open access: yesJournal of Pharmacy & Pharmaceutical Sciences, 2013
The eye is a very complex sensory organ consisting of numerous structures to coordinate the function of sight. It has a series of physical and chemical barriers to help maintain its homeostasis, and mediate environmental exposures.
Nagendra Chemuturi, Jaime A Yanez
doaj   +1 more source

Hydrogel Contact Lens for Extended Delivery of Ophthalmic Drugs

open access: yesInternational Journal of Polymer Science, 2011
Soft contact lenses can improve the bioavailability and prolong the residence time of drugs and, therefore, are ideal drug carriers for ophthalmic drug delivery. Hydrogels are the leading materials of soft contact lenses because of their biocompatibility
Xiaohong Hu   +6 more
doaj   +1 more source

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