The role of Computer Aided Process Engineering in physiology and clinical medicine [PDF]
This paper discusses the potential role for Computer Aided Process Engineering (CAPE) in developing engineering analysis and design approaches to biological systems across multiple levels—cell signalling networks, gene, protein and metabolic networks ...
Allen, R., Bogle, I.D.L., Sumner, T.
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Comparison between “early” or “late” intravitreal injection of dexamethasone implant in branch (BRVO) or central (CRVO) retinal vein occlusion: six months follow-up [PDF]
AIM: The aim of this study was to compare early and late injections of intravitreal dexamethasone implant in patients affected by central retinal vein occlusion (CRVO) or branch retinal vein occlusion (BRVO) with a six-months follow-up.
AUTOLITANO, MONICA +6 more
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This article explores issues relating to mentoring students, particularly ophthalmic nursing students. It highlights the importance of mentorship in learning in practice, which in turn is critical to students' education in a competency-based profession ...
Cox, C. L., Jones, M, Rutkowski, K
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Contact lenses for ophthalmic drug delivery [PDF]
Contact lenses as a means to deliver pharmaceuticals to the eye have seen a significant increase in research interest in the past few years. This review will detail the in vitro experiments which have investigated use of these contact lenses in the context of the desired pharmacological treatment goals in the management of infectious, inflammatory ...
openaire +2 more sources
Suprachoroidal and Subretinal Injections of AAV Using Transscleral Microneedles for Retinal Gene Delivery in Nonhuman Primates. [PDF]
Retinal gene therapy using adeno-associated viruses (AAVs) is constrained by the mode of viral vector delivery. Intravitreal AAV injections are impeded by the internal limiting membrane barrier, while subretinal injections require invasive surgery and ...
Chung, Sook Hyun +7 more
core
Enzyme replacement therapies: What is the best option? [PDF]
Despite many beneficial outcomes of the conventional enzyme replacement therapy (ERT), several limitations such as the high-cost of the treatment and various inadvertent side effects including the occurrence of an immunological response against the ...
Barar, Jaleh +4 more
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Widening use of dexamethasone implant for the treatment of macular edema [PDF]
Sustained-release intravitreal 0.7 mg dexamethasone (DEX) implant is approved in Europe for the treatment of macular edema related to diabetic retinopathy, branch retinal vein occlusion, central retinal vein occlusion, and non-infectious uveitis.
Avitabile T. +9 more
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Next-generation nanomaterials: advancing ocular anti-inflammatory drug therapy
Ophthalmic inflammatory diseases, including conjunctivitis, keratitis, uveitis, scleritis, and related conditions, pose considerable challenges to effective management and treatment.
Jing Wei +5 more
doaj +1 more source
Ophthalmic Drug Delivery through Contact Lenses
Currently available ophthalmic drug delivery systems are inefficient and may lead to side effects. To increase efficiency and reduce side effects, the authors propose disposable particle-laden soft contact lenses for ophthalmic drug delivery.The essential idea is to encapsulate the ophthalmic drug formulations in nanoparticles and to disperse these ...
Derya, Gulsen, Anuj, Chauhan
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Trojan Microparticles Potential for Ophthalmic Drug Delivery [PDF]
The administration of drugs to treat ocular disorders still remains a technological challenge in this XXI century. Although there is an important arsenal of active molecules useful to treat ocular diseases, ranging from classical compounds to biotechnological products, currenty, no ideal delivery system is able to profit all their therapeutic ...
Esteban-Pérez, Sergio +4 more
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