Results 41 to 50 of about 36,131 (273)

The role of Computer Aided Process Engineering in physiology and clinical medicine [PDF]

open access: yes, 2009
This paper discusses the potential role for Computer Aided Process Engineering (CAPE) in developing engineering analysis and design approaches to biological systems across multiple levels—cell signalling networks, gene, protein and metabolic networks ...
Allen, R., Bogle, I.D.L., Sumner, T.
core   +1 more source

Comparison between “early” or “late” intravitreal injection of dexamethasone implant in branch (BRVO) or central (CRVO) retinal vein occlusion: six months follow-up [PDF]

open access: yes, 2017
AIM: The aim of this study was to compare early and late injections of intravitreal dexamethasone implant in patients affected by central retinal vein occlusion (CRVO) or branch retinal vein occlusion (BRVO) with a six-months follow-up.
AUTOLITANO, MONICA   +6 more
core   +1 more source

On being a mentor [PDF]

open access: yes, 2013
This article explores issues relating to mentoring students, particularly ophthalmic nursing students. It highlights the importance of mentorship in learning in practice, which in turn is critical to students' education in a competency-based profession ...
Cox, C. L., Jones, M, Rutkowski, K
core   +1 more source

Contact lenses for ophthalmic drug delivery [PDF]

open access: yesClinical and Experimental Optometry, 2017
Contact lenses as a means to deliver pharmaceuticals to the eye have seen a significant increase in research interest in the past few years. This review will detail the in vitro experiments which have investigated use of these contact lenses in the context of the desired pharmacological treatment goals in the management of infectious, inflammatory ...
openaire   +2 more sources

Suprachoroidal and Subretinal Injections of AAV Using Transscleral Microneedles for Retinal Gene Delivery in Nonhuman Primates. [PDF]

open access: yes, 2020
Retinal gene therapy using adeno-associated viruses (AAVs) is constrained by the mode of viral vector delivery. Intravitreal AAV injections are impeded by the internal limiting membrane barrier, while subretinal injections require invasive surgery and ...
Chung, Sook Hyun   +7 more
core  

Enzyme replacement therapies: What is the best option? [PDF]

open access: yes, 2018
Despite many beneficial outcomes of the conventional enzyme replacement therapy (ERT), several limitations such as the high-cost of the treatment and various inadvertent side effects including the occurrence of an immunological response against the ...
Barar, Jaleh   +4 more
core   +2 more sources

Widening use of dexamethasone implant for the treatment of macular edema [PDF]

open access: yes, 2017
Sustained-release intravitreal 0.7 mg dexamethasone (DEX) implant is approved in Europe for the treatment of macular edema related to diabetic retinopathy, branch retinal vein occlusion, central retinal vein occlusion, and non-infectious uveitis.
Avitabile T.   +9 more
core   +2 more sources

Next-generation nanomaterials: advancing ocular anti-inflammatory drug therapy

open access: yesJournal of Nanobiotechnology, 2023
Ophthalmic inflammatory diseases, including conjunctivitis, keratitis, uveitis, scleritis, and related conditions, pose considerable challenges to effective management and treatment.
Jing Wei   +5 more
doaj   +1 more source

Ophthalmic Drug Delivery through Contact Lenses

open access: yesInvestigative Opthalmology & Visual Science, 2004
Currently available ophthalmic drug delivery systems are inefficient and may lead to side effects. To increase efficiency and reduce side effects, the authors propose disposable particle-laden soft contact lenses for ophthalmic drug delivery.The essential idea is to encapsulate the ophthalmic drug formulations in nanoparticles and to disperse these ...
Derya, Gulsen, Anuj, Chauhan
openaire   +2 more sources

Trojan Microparticles Potential for Ophthalmic Drug Delivery [PDF]

open access: yesCurrent Medicinal Chemistry, 2020
The administration of drugs to treat ocular disorders still remains a technological challenge in this XXI century. Although there is an important arsenal of active molecules useful to treat ocular diseases, ranging from classical compounds to biotechnological products, currenty, no ideal delivery system is able to profit all their therapeutic ...
Esteban-Pérez, Sergio   +4 more
openaire   +3 more sources

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