Results 41 to 50 of about 16,351 (146)
Nanopharmaceuticals for Eye Administration: Sterilization, Depyrogenation and Clinical Applications
As an immune-privileged target organ, the eyes have important superficial and internal barriers, protecting them from physical and chemical damage from exogenous and/or endogenous origins that would cause injury to visual acuity or even vision loss ...
Aleksandra Zielińska +12 more
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Applications of polymers in intraocular drug delivery systems
We are entering a new era of ophthalmic pharmacology where new drugs are rapidly being developed for the treatment of anterior and posterior segment of the eye disease.
Ali Mohammed Alhalafi
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Ocular administration of acetazolamide microsponges in situ gel formulations
In the present work, the antiglaucoma drug, acetazolamide, was formulated as microsponges in situ gel for ocular drug delivery aiming an improved therapeutic efficacy and reduction in the systemic side effects of oral acetazolamide. The microsponges were
Manar M. Obiedallah +2 more
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Drug delivery strategies to improve the treatment of corneal disorders
Anterior eye disorders including dry eye syndrome, keratitis, chemical burns, and trauma have varying prevalence rates in the world. Classical dosage forms based-topical ophthalmic drugs are popular treatments for managing corneal diseases.
Mahsa Fallah Tafti +4 more
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A Potential Application of a Piezoelectric Atomiser for Ophthalmic Drug Delivery
A liquid atomiser composed of a piezoelectric transducer and a metal plate with numerous micro-apertures is studied to identify the most influential factors on its atomising performance.
Wei Xia +4 more
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Contact lenses as drug controlled release systems: a narrative review
Topically applied therapy is the most common way to treat ocular diseases, however given the anatomical and physiological constraints of the eye, frequent dosing is required with possible repercussions in terms of patient compliance.
Helena Prior Filipe +5 more
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Ophthalmic Drug Dosage Forms: Characterisation and Research Methods
This paper describes hitherto developed drug forms for topical ocular administration, that is, eye drops, ointments, in situ gels, inserts, multicompartment drug delivery systems, and ophthalmic drug forms with bioadhesive properties.
Przemysław Baranowski +3 more
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Topical Ocular Drug Delivery: The Impact of Permeation Enhancers
Topical ophthalmic drug delivery targeting the posterior segment of the eye has become a key area of interest due to its non-invasive nature, safety, ease of application, patient compliance, and cost-effectiveness.
Gonçalo Santos +4 more
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The Role of Xenobiotic Transporters in Ophthalmic Drug Delivery
The eye is a very complex sensory organ consisting of numerous structures to coordinate the function of sight. It has a series of physical and chemical barriers to help maintain its homeostasis, and mediate environmental exposures.
Nagendra Chemuturi, Jaime A Yanez
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Hydrogel Contact Lens for Extended Delivery of Ophthalmic Drugs
Soft contact lenses can improve the bioavailability and prolong the residence time of drugs and, therefore, are ideal drug carriers for ophthalmic drug delivery. Hydrogels are the leading materials of soft contact lenses because of their biocompatibility
Xiaohong Hu +6 more
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