Results 61 to 70 of about 3,065,508 (250)

Dendrimeric Systems and Their Applications in Ocular Drug Delivery

open access: yesThe Scientific World Journal, 2013
Ophthalmic drug delivery is one of the most attractive and challenging research area for pharmaceutical scientists and ophthalmologists. Absorption of an ophthalmic drug in conventional dosage forms is seriously limited by physiological conditions.
Burçin Yavuz   +2 more
doaj   +1 more source

Pre-Liposomes: A novel drug delivery system [PDF]

open access: yes, 2019
Preliposomes are a novel drug delivery system (NDDS). Preliposomes, due to their various forms, require further exploration. These structures can deliver both hydrophilic and hydrophobic drugs for cancer, bacterial infections, fungal infections ...
Sheth, Maitry   +3 more
core   +1 more source

Dual‐Targeting Biomimetic Nanozymes Loaded Microneedle Patch Promotes Scarless Wound Healing Through Anti‐Inflammatory and Anti‐Fibrotic Effects

open access: yesAdvanced Science, EarlyView.
This study developed a dual‐targeting biomimetic nanozyme hybrid system (Cu‐CeO2@ABs‐FTP) and integrated it with HAMA hydrogel to fabricate a microneedle patch (CAF@MN). The patch promotes fibroblast‐mediated wound repair, targets macrophages to induce M2 polarization, and targets myofibroblasts to exert anti‐fibrotic effects, thereby enabling rapid ...
Hongyi Zhang   +14 more
wiley   +1 more source

Applications of polymers in intraocular drug delivery systems

open access: yesOman Journal of Ophthalmology, 2017
We are entering a new era of ophthalmic pharmacology where new drugs are rapidly being developed for the treatment of anterior and posterior segment of the eye disease.
Ali Mohammed Alhalafi
doaj   +1 more source

Nanopharmaceuticals for Eye Administration: Sterilization, Depyrogenation and Clinical Applications

open access: yesBiology, 2020
As an immune-privileged target organ, the eyes have important superficial and internal barriers, protecting them from physical and chemical damage from exogenous and/or endogenous origins that would cause injury to visual acuity or even vision loss ...
Aleksandra Zielińska   +12 more
doaj   +1 more source

Contact Lenses: A Promising Drug Delivery System [PDF]

open access: yes, 2019
Presently, around 100 million people are estimated to be wearing contact lenses, and the number is growing exponentially. Though the main use of contact lenses is for improving ametropia problems, they also hold attention as therapeutic devices for the ...
Vedaga, S. B.   +2 more
core   +1 more source

ROS‐Responsive Eye Drop for Controlled Release of 20‐Deoxyingenol Improves Diabetic Corneal Healing by Activating Macrophage Autophagy and Metabolic Reprogramming

open access: yesAdvanced Science, EarlyView.
Schematic illustration of ROS‐responsive TSPBA‐PVA microspheres loaded with 20‐deoxyingenol (TP/20‐DOI) for diabetic corneal wound healing: (a) fabrication and ROS‐triggered release; (b) autophagy activation and metabolic reprogramming in macrophages; (c) suppression of macrophage‐derived CXCL3/CXCL5, attenuation of neutrophil infiltration, and ...
Jiaxin Wu   +20 more
wiley   +1 more source

DESIGN AND EVALUATION OF POLYMERIC OCULAR DRUG DELIVERY SYSTEM FOR CONTROLLED DELIVERY OF CIPROFLOXACIN HYDROCHLORIDE [PDF]

open access: yes, 2012
The field of Ocular drug delivery is one of the interesting and challenging endeavors facing the pharmaceutical scientist. The most frequently used dosage forms i.e.
pawar, sagar dhondiram
core   +1 more source

Potential of Nanoparticle‐Based Phototherapies for Future Treatment of Uveal Melanoma

open access: yesAdvanced Science, EarlyView.
This review evaluates nanoparticle‐based phototherapies for uveal melanoma, highlighting emerging strategies to enhance tumor targeting, light delivery, and treatment precision. Preclinical data indicate improved efficacy and reduced toxicity, supporting their potential to enhance localized treatment and future translational advances. (Generated by the
Emilie Lambert   +8 more
wiley   +1 more source

Quantitative Visualization of Intracellular Nanometabolism Using Peak‐Shifted Dual‐State Emissive FRET Nanoprobes

open access: yesAdvanced Science, EarlyView.
This study reveals the long‐elusive intracellular dissolution mechanism of carrier‐free nanomedicines. By utilizing peak‐shifted dual‐state emissive FRET nanoprobes (PDFNPs) that undergo a distinct ratiometric fluorescence peak shift upon disassembly, we achieve real‐time, quantitative tracking of dissolution kinetics in live cells.
Farsai Taemaitree   +18 more
wiley   +1 more source

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