Results 61 to 70 of about 36,131 (273)

Epidermal Patch Technologies for Integrated Healthcare and Infection Management

Advanced Healthcare Materials, EarlyView.
Epidermal patches have evolved from simple wound coverings into multifunctional, skin‐conformable platforms integrating drug delivery, biosensing, and therapeutic functionalities. This review highlights their material innovations, fabrication strategies, and intelligent designs, including hydrogels, microneedles, and flexible electronics, while ...
Yuqi Wang, Atakan Tevlek, Pawel L. Urban, Boaz Mizrahi, Onome Ejeromedoghene, Roshan Deen, Yuanjing Lin, Jagan Mohan Dodda   +7 more
wiley   +1 more source

Nanopharmaceuticals for Eye Administration: Sterilization, Depyrogenation and Clinical Applications

Biology, 2020
As an immune-privileged target organ, the eyes have important superficial and internal barriers, protecting them from physical and chemical damage from exogenous and/or endogenous origins that would cause injury to visual acuity or even vision loss ...
Aleksandra Zielińska, Beatriz B. Soles, Ana R. Lopes, Beatriz F. Vaz, Camila M. Rodrigues, Thais F. R. Alves, Dorota Klensporf-Pawlik, Alessandra Durazzo, Massimo Lucarini, Patricia Severino, Antonello Santini, Marco V. Chaud, Eliana B. Souto   +12 more
doaj   +1 more source

Intravitreal injection of Ozurdex(®) implant in patients with persistent diabetic macular edema, with six-month follow-up [PDF]

, 2016
AIM: To evaluate the efficacy of intravitreal dexamethasone injections in diabetic macular edema (DME). METHODS: A 700 μg slow-release intravitreal dexamethasone implant (Ozurdex®) was placed in the vitreal cavity of 17 patients (19 eyes) affected ...
Bottone, A, FAMELI, VALERIA, Ferraresi, AF, Giustolisi, R, Lenzi, T, PACELLA, Elena, Pacella, F, Romano, MR, Turchetti, P   +8 more
core   +2 more sources

Metamaterial Antennas Enhance MRI of the Eye and Occipital Brain

Advanced Materials, EarlyView.
A radiofrequency antenna platform comprising planar and bend configurations is developed, incorporating structurally integrated epsilon‐negative metamaterial unit cells to enhance MRI. These antennas enable high‐resolution in vivo human MRI of the eye, orbit, and occipital brain. Comprehensive validation, including simulations, phantom experiments, SAR,
Nandita Saha, Bilguun Nurzed, Mostafa Berangi, Andre Kuehne, Helmar Waiczies, Igor Fabian Tellez Ceja, Xiang Hu, Thomas Gladytz, Lisa Krenz, Dave Huebler, Beate Endemann, Claudia Brockmann, Ebba Beller, Oliver Stachs, Thoralf Niendorf   +14 more
wiley   +1 more source

Mucoadhesive microparticles engineered for ophthalmic drug delivery [PDF]

Journal of Physics and Chemistry of Solids, 2008
Although topical drug delivery is a convenient route of administration to treat various eye diseases, it has serious limitations due to rapid clearance of the formulation from the surface of the eye. In this study, we engineered microparticles for both sustained drug delivery and prolonged residence time on the extraocular surface.
Young, Bin Choy, Jung-Hwan, Park, Mark R, Prausnitz   +2 more
openaire   +2 more sources

Therapeutic approaches with intravitreal injections in geographic atrophy secondary to age-related macular degeneration: current drugs and potential molecules [PDF]

, 2019
The present review focuses on recent clinical trials that analyze the efficacy of intravitreal therapeutic agents for the treatment of dry age-related macular degeneration (AMD), such as neuroprotective drugs, and complement inhibitors, also called ...
Cerini, Alberto, Greco A., La Cava M, Lambiase A, Limoli PG, Nebbioso M   +5 more
core   +1 more source

Toward Wireless Implantable Robotic Systems Driven by Magnetic Field for Personalized Therapy

Advanced Robotics Research, EarlyView.
Robotic materials are playing an increasingly vital role in enabling sensing and actuation at small scales. This perspective highlights recent advances in magnetic materials and magnetically actuated devices for wireless sensing, actuation, and energy harvesting toward implantable robotic systems for closed‐loop therapy.
Yusheng Wang, Ruijian Ge, Xiaoguang Dong
wiley   +1 more source

Applications of polymers in intraocular drug delivery systems

Oman Journal of Ophthalmology, 2017
We are entering a new era of ophthalmic pharmacology where new drugs are rapidly being developed for the treatment of anterior and posterior segment of the eye disease.
Ali Mohammed Alhalafi
doaj   +1 more source

Mobility Experiments With Microrobots for Minimally Invasive Intraocular Surgery [PDF]

, 2013
Purpose.: To investigate microrobots as an assistive tool for minimally invasive intraocular surgery and to demonstrate mobility and controllability inside the living rabbit eye.
Bergeles, C, Chatzipirpiridis, G, Ergeneman, O, Erni, S, Framme, C, Nelson, BJ, Pané, S, Pokki, J, Ullrich, F   +8 more
core   +1 more source

Tumbling Magnetic Microrobots for Targeted In Vivo Drug Delivery in the GI Tract

Advanced Robotics Research, EarlyView.
We introduce a microrobot design and integrated system for on‐demand targeted drug release in the gastrointestinal tract. The microrobot has an embedded magnet for actuation with external magnetic fields and is visualized in real time using ultrasound. It has two drug release ports sealed with a thermally sensitive wax. Local heating of the wax using a
Aaron C. Davis, Luis Carlos Sanjuan Acosta, Shubh P. Mehta, Baiyan Qi, Yang Yang, Luis Solorio, Craig J. Goergen, David J. Cappelleri   +7 more
wiley   +1 more source