Results 101 to 110 of about 7,064 (119)

Design of photoinitiator-functionalized hydrophilic nanogels with uniform size and excellent biocompatibility

Polymer Chemistry, 2019
Three well-controlled biocompatible hydrophilic nanogels were synthesized, and they can effectively initiate photopolymerization and improve the mechanical properties of polymers.
Meng Wei, Yanjing Gao, Shengling Jiang, Jun Nie, Fang Sun   +4 more
openaire   +1 more source

Core cross-linked nanogels based on the self-assembly of double hydrophilic poly(2-oxazoline) block copolymers

Journal of Materials Chemistry B, 2015
The synthesis of poly(2-oxazoline)-based block copolymers consisting of a cationic and a hydrophilic segment is described.
Matthias, Hartlieb, David, Pretzel, Michael, Wagner, Stephanie, Hoeppener, Peter, Bellstedt, Matthias, Görlach, Christoph, Englert, Kristian, Kempe, Ulrich S, Schubert   +8 more
openaire   +2 more sources

Hydrogels and Nanogels: Pioneering the Future of Advanced Drug Delivery Systems

Pharmaceutics
Conventional drug delivery approaches, including tablets and capsules, often suffer from reduced therapeutic effectiveness, largely attributed to inadequate bioavailability and difficulties in ensuring patient adherence.
E. J. Delgado-Pujol, Guillermo Martínez, David Casado-Jurado, Juan Vázquez, Jesús León-Barberena, David Rodríguez‐Lucena, Y. Torres, A. Alcudia, B. Begines   +8 more
semanticscholar   +1 more source

Functional Dendrimer Nanogels for DNA Delivery and Gene Therapy of Tumors

Angewandte Chemie
Solving the dilemma between efficacy and cytotoxicity of cationic colloidal vectors is one of the biggest challenges in gene delivery. Cationic dendrimer assemblies with hierarchical structure, smart and biomimetic behaviors have been developed for drug ...
Xin Li, Zhijun Ouyang, Laura Hetjens, Ming Ni, Kuailu Lin, Yong Hu, Xiangyang Shi, A. Pich   +7 more
semanticscholar   +1 more source

Self-Assembled Degradable Nanogels Provide Foliar Affinity and Pinning for Pesticide Delivery by Flexibility and Adhesiveness Adjustment.

ACS Nano, 2021
At present, it is highly important to develop a simple and compatible nano delivery system for pesticides for foliar application, which can improve their insecticidal efficacy and resistance to adverse climates while reducing the environmental risks ...
Jian Luo, Yue Gao, Yukun Liu, Xue-Ping Huang, Da‐xia Zhang, Haichao Cao, Tong-fang Jing, Feng Liu, Beixing Li   +8 more
semanticscholar   +1 more source

Platinum-Coordinated Dual-Responsive Nanogels for Universal Drug Delivery and Combination Cancer Therapy.

Small, 2022
Developing a universal nanoplatform for efficient delivery of various drugs to target sites is urgent for overcoming various biological barriers and realizing combinational cancer treatment.
Qiu‐Yi Duan, Ya-Xuan Zhu, Hao-Ran Jia, Yuxin Guo, Xinping Zhang, Ruihan Gu, Chengcheng Li, Fu‐Gen Wu   +7 more
semanticscholar   +1 more source

Abstract 3099: pH-regulated hydrophilicity/hydrophobicity-, surface charge-reversible and redox sensitive nanogels for anticancer drug delivery

Cancer Research, 2017
Abstract Long circulation in blood, enhanced tumor accumulation and penetration, efficient cellular internalization and intracellular drug release are major challenges in the development of ideal anticancer drug delivery systems. Although several strategies have been reported to improve therapeutic efficacy, they mainly meet one or a few
Hao Yang, Qin Wang, Fuying Li, Yanhong Zhu, Lu Gan, Xiangliang Yang   +5 more
openaire   +1 more source

Mucoadhesive, Antibacterial, and Reductive Nanogels as a Mucolytic Agent for Efficient Nebulized Therapy to Combat Allergic Asthma.

ACS Nano, 2022
Asthma is an intractable disease involving the infiltration of inflammatory cells and mucus plugging. Despite small molecular mucolytics having the ability to break the disulfide bonds of mucins, offering a potential way to overcome the airflow ...
Dan Zhao, Dong Li, Xueliang Cheng, Zheng Zou, Xuesi Chen, Chaoliang He   +5 more
semanticscholar   +1 more source

A novel thermo-sensitive nanogel composing of poly(N-isopropylacrylamide) grafted onto alginate-modified graphene oxide for hydrophilic anticancer drug delivery

Journal of the Iranian Chemical Society, 2017
Nanogels have been demonstrated to be desirable for hydrophilic anticancer drug delivery. This study presents a novel nanogel consisting of sodium alginate-modified graphene oxide (SA-GO) and N-isopropylacrylamide (NIPAM) for sustained delivery of doxorubicin (DOX) drug.
Ghasem Rezanejade Bardajee, Zari Hooshyar   +1 more
openaire   +1 more source

Hydrophilic Nanogels : Characterization and Behavior in Biological Environment

2011
Hydrophilic nanocarriers, formed by electrostatic interaction between their oppositely charged components, are recognized as nanomaterials with an enormous potential as vectors in biomedical and pharmaceutical applications. However, comprehensive information about their fate in various biological environments is still lacking.
openaire   +1 more source