Results 181 to 190 of about 5,129,522 (237)
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3-Hydroxyisoxazole-5-hydroxamic acid
Journal of Medicinal Chemistry, 1977The synthesis of the title compound, 3-hydroxyisoxazole-5-hydroxamic acid (4b), by two procedures is described. The first, involving the treatment of dimethyl acetylenedicarboxylate with hydroxylamine, had previously been reported to give the 3-hydroxyisoxazole-5-carboxylic acid (4a).
J W, Hines, C H, Stammer
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Hydroxamic acid oxidation-pharmacological considerations
Biochemical Pharmacology, 1978Abstract Both primary and secondary hydroxamic acids were found to be quite susceptible to oxidation by 2,6-dichlorophenolindophenol at physiological pH. Among the primary hydroxamates, substituted benzhydroxamic acids were more easily oxidized than aliphatic derivatives, resonance being an important factor determining relative rates.
S H, Blobstein +3 more
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Hydroxamic acids as colorimetric reagents
Talanta, 1966Thirty-three hydroxamic acids and three N-substituted hydroxamic acids or structurally similar compounds have been studied as possible colorimetric reagents for metal ions. They were tested with 78 ions under varying conditions of acidity and basicity.
V C, Bass, J H, Yoe
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The Journal of Organic Chemistry, 2009
A continuous flow tubing reactor can be used to readily transform methyl or ethyl carboxylic esters into the corresponding hydroxamic acids. Flow rate, reactor volume, and temperature were optimized for the preparation of a small collection of hydroxamic acids. Synthetic advantages were identified as an increased reaction rate and higher product purity.
E. Riva +6 more
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A continuous flow tubing reactor can be used to readily transform methyl or ethyl carboxylic esters into the corresponding hydroxamic acids. Flow rate, reactor volume, and temperature were optimized for the preparation of a small collection of hydroxamic acids. Synthetic advantages were identified as an increased reaction rate and higher product purity.
E. Riva +6 more
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1969
Publisher Summary This chapter summarizes the methods available for the synthesis of cyclic hydroxamic acids––to outline their characteristic reactions, and to present some useful physical data. Their synthesis, some biological and physical properties are also reviewed.
J.B. Bapat, D.S.T.C. Black, R.F.C. Brown
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Publisher Summary This chapter summarizes the methods available for the synthesis of cyclic hydroxamic acids––to outline their characteristic reactions, and to present some useful physical data. Their synthesis, some biological and physical properties are also reviewed.
J.B. Bapat, D.S.T.C. Black, R.F.C. Brown
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Hydroxamic acids I: Factors affecting the stability of the hydroxamic acid-iron complex
Journal of Pharmaceutical Sciences, 1969The utility of hydroxamic acid formation and subsequent iron complexation as an analytical tool for succinimide has been investigated. Several factors affecting the stability of the hydroxamic acid-ferric iron complex have been studied and critical factors in the stability of the complex have been established.
R E, Notari, J W, Munson
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Photochemistry of hydroxamic acids
Tetrahedron, 1987Abstract Photochemical reactions of hydroxamic acids have been studied. The intermediacy of a RCONH radical is postulated, based on oxidations achieved with DCA under photochemical conditions.
B.D. Hosangadi +3 more
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Urease inhibition by hydroxamic acids
Experientia, 1981Ureases from jack beans andRhodototorula pilimanae were observed to be inhibited by primary hydroxamic acids but were not inhibited by acyclic-secondary (N-alkyl) hydroxamic acids.
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Biologically active quinazoline-based hydroxamic acids
Medicinal Chemistry Research, 2020V. Osipov, D. Khachatryan, A. Balaev
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Hydroxamic acids. III. Mass spectra of substituted hydroxamic acids and cyclic imides
Australian Journal of Chemistry, 1969Aryl hydroxamic acid derivatives fragment in a diagnostic manner upon electron impact. A hydroxamic acid containing both styryl and benzyl substituents undergoes skeletal-rearrangement of the type ABC ? AC+B. The mass spectra of the O- and N-acetyl derivatives of O- benzylhydroxamic acids are indistinguishable. M-CO2 fragments are again observed in the
JH Bowie, MTW Hearn, AD Ward
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