Results 51 to 60 of about 7,137 (264)

Transient Transcriptional Regulation of the CYS-C1 Gene and Cyanide Accumulation upon Pathogen Infection in the Plant Immune Response [PDF]

open access: yes, 2013
Cyanide is produced concomitantly with ethylene biosynthesis. Arabidopsis (Arabidopsis thaliana) detoxifies cyanide primarily through the enzyme b-cyanoalanine synthase, mainly by the mitochondrial CYS-C1.
Bejarano, Eduardo R.   +3 more
core   +1 more source

Successful Renal Transplantation after Presumed Cyanide Toxicity Treated with Hydroxocobalamin and Review of the Literature

open access: yesCase Reports in Transplantation, 2018
We report two cases of successful renal transplantation with allografts from donors who suffered anoxic brain injury as the primary cause of death from house fires.
Ryan J. Hendrix   +5 more
doaj   +1 more source

The use of intravenous hydroxocobalamin as a rescue in methylene blue-resistant vasoplegic syndrome in cardiac surgery

open access: yesAnnals of Cardiac Anaesthesia, 2017
Vasoplegic syndrome is a well-recognized complication during cardiopulmonary bypass (CPB) and is associated with increased morbidity and mortality, especially when refractory to conventional vasoconstrictor therapy.
Yi Cai   +3 more
doaj   +1 more source

Receiving a diagnosis of Pernicious Anaemia: exploring experiences of relationships with health professionals [PDF]

open access: yes, 2019
Objectives: Pernicious Anaemia (PA) is a chronic condition caused by vitamin B12 deficiency. This is a qualitative study using interpretative phenomenological analysis (IPA); which aimed to explore the patients lived experience of diagnosis and ...
Glover, E., Mercer, Jenny, Seage, Heidi
core   +1 more source

The use of hydroxocobalamin for vasoplegic syndrome in left ventricular assist device patients

open access: yesClinical Case Reports, 2020
We demonstrate evidence supporting the efficacy of hydroxocobalamin in reducing vasopressor requirements for LVAD patients with refractory vasoplegia. Further study is needed to substantiate these findings and determine its optimal use in practice.
Brian Ayers   +4 more
doaj   +1 more source

Biphasic Modulation of NOS Expression, Protein and Nitrite Products by Hydroxocobalamin Underlies Its Protective Effect in Endotoxemic Shock: Downstream Regulation of COX-2, IL-1 beta, TNF-alpha, IL-6, and HMGB1 Expression [PDF]

open access: yes, 2013
Background. NOS/•NO inhibitors are potential therapeutics for sepsis, yet they increase clinical mortality. However, there has been no in vivo investigation of the (in vitro) •NO scavenger, cobalamin’s (Cbl) endogenous effects on NOS/•NO/inflammatory ...
Brancaleone, V   +5 more
core   +3 more sources

Safe and effective prescribing with dyslexia [PDF]

open access: yes, 2019
Background: The term ‘dyslexia’ refers to a condition that impacts upon reading and writing abilities whilst not altering intelligence. Individuals with dyslexia may have difficulties with the speed and accuracy and their reading and writing, amongst ...
Anderson, John L   +3 more
core   +1 more source

Long-term outcome of a patient with Transcobalamin deficiency caused by the homozygous c.1115_1116delCA mutation in TCN2 gene: a case report

open access: yesItalian Journal of Pediatrics, 2021
Background Transcobalamin deficiency is a rare autosomal recessive inborn error of cobalamin transport (prevalence:
Francesco Martino   +6 more
doaj   +1 more source

Vitamin B12 status in infancy and the effect of a vitamin B12 injection in infants with subclinical vitamin B12 deficiency: study protocol for a register-based randomised controlled trial

open access: yesBMJ Open, 2023
Introduction Vitamin B12 (cobalamin) is crucial for optimal child development and growth, yet deficiency is common worldwide. The aim of this study is twofold; (1) to describe vitamin B12 status and the status of other micronutrients in Norwegian infants,
Ingrid Kvestad   +9 more
doaj   +1 more source

Protein dynamics in the reductive activation of a B12-containing enzyme [PDF]

open access: yes, 2017
B12-dependent proteins are involved in methyl transfer reactions ranging from the biosynthesis of methionine in humans to the formation of acetyl-CoA in anaerobic bacteria.
Goetzl, Sebastian   +6 more
core   +1 more source

Home - About - Disclaimer - Privacy