Results 51 to 60 of about 8,578 (226)
Opera and poison : a secret and enjoyable approach to teaching and learning chemistry [PDF]
The storyline of operas, with historical or fictional characters, often include potions and poisons. This has prompted a study of the chemistry behind some operatic plots.
Bentley R. +43 more
core +2 more sources
SummaryIntestinal absorption of large oral doses of hydroxocobalamin and cyanocobalamin (100,. 500 and 1000 μg) was compared and quantitated in 17 normal subjects using a double label isotope technique.In 3 pairs of normal individuals, Co57-labeled cyanocobalamin and Co60-labeled hydroxocobalamin were administered simultaneously in oral doses of 100 ...
George B. Jerzy Glass, Herbert Weisberg
openaire +3 more sources
Hemodialysis Failure Secondary to Hydroxocobalamin Exposure [PDF]
Hydroxocobalamin is a recently approved antidote for the treatment of cyanide poisoning. The case presented involves a young patient administered empiric hydroxocobalamin due to suspected cyanide overdose. Due to the development of acute kidney injury and severe metabolic derangement, emergent hemodialysis was initiated. Unfortunately, hemodialysis was
John K. Tucker +7 more
openaire +3 more sources
Redirecting Intermediary Metabolism to Counteract Cyanide Poisoning
Cyanide is coined “the classic metabolic poison”; however, FDA‐approved cyanide chelators do not counteract cyanide's metabolic damage. Here, we review the mechanisms of cyanide toxicity, with a focus on intermediary metabolism. We present the theory that, within the innate plasticity of the metabolome, there may reside metabolic pathways that can ...
Vik S. Bebarta, Anjali K. Nath
wiley +1 more source
Site directed mutagenesis of L-pyrrolysine in dimethylamine methyltransferase [PDF]
Methanosarcina barkeri is an archaeon and is able to use methylamines as growth substrates for methanogenesis. The methylamine methyltransferases that are involved in initiating methanogenesis from the methylamines have an in-frame amber codon (UAG) that
Patel, Jigar
core
The Explanatory Indispensability of Memory Traces [PDF]
During the first half of the twentieth century, many philosophers of memory opposed the postulation of memory traces based on the claim that a satisfactory account of remembering need not include references to causal processes involved in recollection ...
De Brigard, Felipe
core
Gene identification for the cblD defect of vitamin B12 metabolism [PDF]
Background Vitamin B12 (cobalamin) is an essential cofactor in several metabolic pathways. Intracellular conversion of cobalamin to its two coenzymes, adenosylcobalamin in mitochondria and methylcobalamin in the cytoplasm, is necessary for the ...
Baumgartner, M R +7 more
core +1 more source
Molecular and functional experiments highlight the relevance of species‐specific polymorphisms in a B12 riboswitch of the Mycobacterium genus. This information provided proof‐of‐concept to engineer a whole‐cell biosensor capable of detecting vitamin B12. ABSTRACT Vitamin B12 metabolism differs among members of the Mycobacterium genus.
Elena Campos‐Pardos +6 more
wiley +1 more source
Cyanide in breath as a marker for cyanide poisoning [PDF]
Approximately 120 people die every year due to fires in Sweden. A majority of the fire victims die due to toxic fire gases. Carbon monoxide is often thought to be the major cause of death. Still, another very toxic fire gas, hydrogen cyanide, is formed
Stamyr, Kristin
core +1 more source
The concomitant use of metformin and PPI was significantly associated with an increased risk of vitamin B12 deficiency in patients with type 2 diabetes. ABSTRACT Introduction Vitamin B12 deficiency is one of the adverse drug reactions of metformin and proton pump inhibitors (PPIs).
Choungwon Jung, Soyoung Park, Hyunah Kim
wiley +1 more source

