Axial Ligation and Redox Changes at the Cobalt Ion in Cobalamin Bound to Corrinoid Iron-Sulfur Protein (CoFeSP) or in Solution Characterized by XAS and DFT [PDF]
, 2016 A cobalamin (Cbl) cofactor in corrinoid iron-sulfur protein (CoFeSP) is the primary methyl group donor and acceptor in biological carbon oxide conversion along the reductive acetyl-CoA pathway.
Dau, Holger +6 more
core +3 more sources
Severe Hemolytic Crisis in Uncontrolled AIHA Triggered by Dengue
Case Reports in Medicine, Volume 2025, Issue 1, 2025.We present the case of a woman with a history of autoimmune hemolytic anemia (AIHA), untreated for 1 year, who presented with fever, myalgia, arthralgia, anemia, and thrombocytopenia, along with a positive nonstructural protein antigen 1 (NS1Ag) test. During the course of dengue, the patient developed severe hemolytic anemia, posing a potentially life ...
Christian Alberto Rodriguez-Saldaña +6 more
wiley +1 more source
The Immunomodulatory Effect of Vitamin B12 in Pernicious Anemia: A Systematic Review
Oxidative Medicine and Cellular Longevity, Volume 2025, Issue 1, 2025.Objectives: The aim of this review is to draw attention to key findings from various published studies concerning the effect of methylcobalamin/cyanocobalamin on the immune response of patients diagnosed with pernicious anemia (PA). Methods: This systematic review followed the Preferred Reporting Items for Systematic Reviews and Meta‐Analyses (PRISMA ...
Tesfaye Engdaw Habtie +6 more
wiley +1 more source
Hong Kong Poison Information Centre: Annual report 2021
Hong Kong Journal of Emergency Medicine, Volume 31, Issue 6, Page 339-353, December 2024.Abstract Introduction The Hong Kong Poison Information Centre (HKPIC) has been providing consultation services to healthcare professionals and collecting epidemiological data on poisoning in Hong Kong since 2005. Objective To analyse and report the poisoning data from HKPIC in 2021.
Tin Yat Anthony Chow +3 more
wiley +1 more source
Isolation of Cyanide Hydratase Mutants from Gloeocerospora Sorghi at alkaline pH [PDF]
, 2013 Cyanide is both a useful and dangerous chemical compound that serves as a crucial component in multiple industrial processes, including metal mining.
Lessen, Henry Joseph
core +1 more source
A systematic review and meta‐analysis of functional vitamin B12 status among adult vegans
Nutrition Bulletin, Volume 49, Issue 4, Page 463-479, December 2024.Abstract The dietary intake of vitamin B12 among unsupplemented vegans is notably lower compared to both vegetarians and omnivores. Prolonged low intakes of vitamin B12, such as seen in those adhering to a vegan diet, lead to physiological deficiency of vitamin B12 and an elevated risk of B12‐related morbidity.
Ali Niklewicz +3 more
wiley +1 more source
Contributions of Sequence and Structure to Ligand Selectivity in Class II Cobalamin Riboswitches [PDF]
, 2016 Riboswitches are gene regulatory elements found in the 5’-untranslated region of many bacterial genes. The direct binding of small molecule ligands induces conformational changes in the RNA that influence downstream expression machinery and determine the
Webster, Samantha M
core +2 more sources
Nasal Drug Delivery Systems: An Overview [PDF]
, 2015 Since ancient times, drugs have been administered via the nasal route for therapeutic and recreational purposes. The interest in, and importance, of the systemic effects of drugs administered through the nasal route, have expanded over recent decades ...
Conway, Barbara R. +3 more
core +1 more source
Microangiopathic thrombocytopenia caused by vitamin B12 deficiency responding to plasma exchange
British Journal of Haematology, Volume 205, Issue 4, Page 1546-1550, October 2024.Summary A young adult African American female presented with normocytic microangiopathic haemolytic anaemia, elevated lactate dehydrogenase and thrombocytopenia. The patient responded to therapeutic plasma exchanges (TPE) for presumed thrombotic microangiopathy caused by thrombotic thrombocytopenic purpura (TTP).
Denis M. Dwyre +5 more
wiley +1 more source
Efficacy of methylcobalamin to normalise elevated homocysteine of vitamin B12 deficient vegetarians: a double blind placebo control study [PDF]
, 2015 Vegetarians are known to be deficient in vitamin B12, due to a lack of dietary animal products, which can elevate plasma total homocysteine (tHcy). Elevated total tHcy can render vegetarians susceptible to cardiovascular disease (CVD).
Chappell, David +3 more
core +1 more source