Results 31 to 40 of about 1,195,570 (202)

Stereocontrolled Asymmetric Synthesis of α-Hydroxy-β-amino Acids. A Stereodivergent Approach

, 2016
The stereocontrolled asymmetric synthesis of α-hydroxy-β-amino acids has been investigated via the Lewis acid-promoted cyanation of (5R,6S)-2-acetoxy-4-(benzyloxycarbonyl)-5,6-diphenyl-2,3,5,6-tetrahydro-4H-1,4-oxazines with trimethylsilyl cyanide.
Yutaka Aoyagi (633479), Robert M. Williams (1333935), Rajendra P. Jain (2700721)   +2 more
core   +1 more source

Synthesis of conformationally constrained hydroxy-alfa-amino acids by intramolecular conjugate addition [PDF]

, 2000
An efficient and easily applicable method for the synthesis of a variety of hydroxy--amino acids analogues of serine and phenylalanine has been established.
Peregrina, J.M., Busto, J.H., Avenoza, A., Cativiela, C.   +3 more
core   +1 more source

Occurrence of 3 beta-hydroxy-5-cholestenoic acid, 3 beta,7 alpha-dihydroxy-5-cholestenoic acid, and 7 alpha-hydroxy-3-oxo-4-cholestenoic acid as normal constituents in human blood.

Journal of Lipid Research, 1988
Three unconjugated C27 bile acids were found in plasma from healthy humans. They were isolated by liquid-solid extraction and anion-exchange chromatography and were identified by gas-liquid chromatography-mass spectrometry, microchemical reactions, and ...
M Axelson, B Mörk, J Sjövall
doaj   +1 more source

Construction of fatty acid derivatives from rubber seed oil as α-glucosidase inhibitors based on rubber seed oil

Bioresources and Bioprocessing, 2022
Natural free fatty acids show inhibitory effects on α-glucosidase and can hence have potential applications in diabetes treatment. This study indicated that the inhibitory effect of fatty acids showed a significant negative correlation with affinity ...
Jiahao Liu, Renwei Zhang, Kaili Nie, Changsheng Liu, Li Deng, Fang Wang   +5 more
doaj   +1 more source

Identification of unusual 7-oxygenated bile acid sulfates in a patient with Niemann-Pick disease, type C1

Journal of Lipid Research, 2001
Niemann-Pick disease, type C, was diagnosed in a 3-month-old boy with hepatosplenomegaly, mild signs of cholestasis, hepatic inflammation and extramedullary erythropoesis, together with chronic airway disease. He developed muscular hypotonia, psychomotor
Gunvor Alvelius, Ola Hjalmarson, William J. Griffiths, Ingemar Björkhem, Jan Sjövall   +4 more
doaj   +1 more source

Time-resolved fluorescence-based europium-derived probes for peroxidase bioassays, citrate cycle imaging and chirality sensing [PDF]

, 2005
The dissertation describes the development of europium-derived fluorescence probes for biological substances in aqueous solution. A scheme is shown in Fig. 7.1.
Lin, Zhihong
core   +1 more source

Monocyclic Phenolic Acids; Hydroxy- and Polyhydroxybenzoic Acids: Occurrence and Recent Bioactivity Studies

Molecules, 2010
Among the wide diversity of naturally occurring phenolic acids, at least 30 hydroxy- and polyhydroxybenzoic acids have been reported in the last 10 years to have biological activities.
Robin J. Marles, Shahriar Khadem
doaj   +1 more source

Hydrocarbons, sterols and hydroxy acids in Antarctic mosses

Antarctic Record, 1985
Hydrocarbons, sterols and hydroxy acids were studied in Antarctic mosses, Pottia heimii, Sarconeurum glaciale and Bryum pseudotriquetrum, to characterize their composition and to find their biogeochemical markers, collected from the Miers Valley of ...
Genki I. Matsumoto, Hiroshi Kanda
doaj   +1 more source

FA2H is responsible for the formation of 2-hydroxy galactolipids in peripheral nervous system myelins⃞

Journal of Lipid Research, 2008
Myelin in the mammalian nervous system has a high concentration of galactolipids [galactosylceramide (GalCer) and sulfatide] with 2-hydroxy fatty acids.
Eduardo N. Maldonado, Nathan L. Alderson, Paula V. Monje, Patrick M. Wood, Hiroko Hama   +4 more
doaj   +1 more source

Fatty acid hydratases for hydroxy fatty acid bioproduction

Invention Disclosure
Hydroxy fatty acids are an emerging class of compounds with growing industrial and medicinal significance, yet their chemical synthesis remains challenging.
Yu Chyuan Heng, Sandra Kittelmann
doaj   +1 more source