Results 81 to 90 of about 1,267,051 (281)

Food, Fatty Acids and Antioxidants Intake and their Associations with Atopic disease in Adults [PDF]

open access: yes, 2011
It was hypothesized that high fat consumption, specifically from polyunsaturated fatty acids, may be positively related to atopic disease prevalence.
Trak-Fellermeier, María Angélica
core   +1 more source

Effects of fatty acids on inflammatory markers studied in vivo and in vitro

open access: yes, 2008
Inflammation involves interactions amongst many different cell types as a defense mechanism of the body. Inflammation is also involved in cardiovascular disease (CVD).
Mohd Yusof, Hayati
core   +1 more source

Fatty acid metabolism in Serratia marcescens: III. The constituent fatty acids of the cell

open access: yesJournal of Lipid Research, 1963
An analysis of the lipids of the bacterium Serratia marcescens has shown that palmitic acid and 9,10-methylenehexadecanoic acid constitute about 75% of the total fatty acids.
D.G. Bishop, J.L. Still
doaj   +1 more source

ACSL4‐Dependent Lysosomal Lipid Peroxidation Links WTAP‐Mediated m6A Modification to Intervertebral Disc Degeneration

open access: yesAdvanced Science, EarlyView.
IL‐1β upregulates the protein level of WTAP, which promotes the m6A modification of ACSL4 mRNA in an IGF2BP2‐dependent manner, thereby enhancing its stability. The increased ACSL4 drives lipid peroxidation, leading to lysosomal membrane permeabilization (LMP) and impaired mitophagy, which collectively accelerate intervertebral disc degeneration (IVDD).
Shu Jia   +8 more
wiley   +1 more source

Beyond Nature's Blueprint: Macrocyclic Peptides Containing Unnatural Amino Acids in Therapeutic Development

open access: yesAngewandte Chemie, EarlyView.
Strategic incorporation of unnatural amino acids transforms macrocyclic peptides into drug‐like molecules capable of engaging challenging targets. These building blocks enhance stability, permeability, and bioavailability, accelerating the development of next‐generation peptide therapeutics.
Krishna K. Sharma   +5 more
wiley   +2 more sources

Integrated O2 and H2 Gas Therapy via Microneedle‐Assisted Photocatalytic Water Splitting for Accelerating Diabetic Full‐Thickness Skin Wound Healing

open access: yesAdvanced Science, EarlyView.
A concept of integrated O2 and H2 gas therapy is achieved using a gas‐producing material. PMP nanoparticles, fabricated from platinum, MIL‐101(Fe)‐NH2, and phosphotungstic acid, are integrated into bilayer gelatin methacryloyl microneedles for transdermal delivery. These microneedles enable integrated O2 and H2 gas therapy and promote wound healing via
Zesheng Chen   +13 more
wiley   +1 more source

Structure and Biosynthesis of Mangotoxin Produced by the Plant Pathogen Pseudomonas syringae

open access: yesAngewandte Chemie, EarlyView.
The structure of mangotoxin remained elusive for over two decades. Here, mangotoxin was isolated from the native producer, Pseudomonas syringae pv. syringae, and was determined to be an alkyne‐containing dipeptide. Mangotoxin inhibited the growth of multidrug‐resistant human pathogen Klebsiella pneumoniae.
Alexis H. Murray   +4 more
wiley   +2 more sources

Gageostatins A–C, Antimicrobial Linear Lipopeptides from a Marine Bacillus subtilis

open access: yesMarine Drugs, 2014
Concerning the requirements of effective drug candidates to combat against high rising multidrug resistant pathogens, we isolated three new linear lipopeptides, gageostatins A–C (1–3), consisting of hepta-peptides and new 3-β-hydroxy fatty acids from the
Fakir Shahidullah Tareq   +5 more
doaj   +1 more source

The Cancer Cell Metabolic Reprogramming Remodels the Tumor Microenvironment: Molecular Mechanisms and Therapeutic Strategies

open access: yesAdvanced Science, EarlyView.
This review elucidates how cancer cell metabolic reprogramming—across glucose, lipid, amino acid, and nucleotide pathways—remodels the tumor microenvironment to suppress anti‐tumor immunity and promote immune escape. Targeting these metabolic axes offers promising strategies to overcome immunotherapy resistance and enhance cancer treatment.
Guoqing Xiang   +5 more
wiley   +1 more source

Effects of fatty acids on inflammatory markers studies in vitro and in vivo

open access: yes, 2008
Inflammation involves interactions amongst many different cell types as a defense mechanism of the body. Inflammation is also involved in cardiovascular disease (CVD).
Mohd Yusof, Hayati
core   +1 more source

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