Essential fatty acids and their long-chain polyunsaturated metabolites in maternal and cord plasma triglycerides during late gestation [PDF]
The fatty acid composition of plasma lipids was determined in 41 pairs of mothers and their term infants at time of birth (38-42 postmenstrual weeks) by high-resolution capillary gas-liquid chromatography, Linoleic and alpha-linolenic acids were found at
Koletzko, Berthold +2 more
core +1 more source
Structures of the 2-hydroxy unsaturated fatty acids of pig brain sphingolipids
The structural characterization of the 2-hydroxy monounsaturated fatty acids of pig brain sphingolipids is described. The acids were isolated via the copper chelate and converted to the 2-methoxy methyl esters.
Yasuo Kishimoto, Norman S. Radin
doaj +1 more source
Genetic ablation of Cep55 in Pten‐deficient mouse models delays tumorigenesis. Integrated multi‐omics analyses (proteomics, phosphoproteomics, and spatial transcriptomics) reveal that CEP55 regulates oncogenic signaling (RAS/ERK, PI3K/AKT), integrin/FAK‐mediated adhesion, extracellular matrix (ECM) remodeling, and endocytosis.
Behnam Rashidieh +22 more
wiley +1 more source
Omega 3 fatty acids and cognitive health in older people. [PDF]
Oily fish and other sources of long-chain n-3 polyunsaturated fatty acids (n-3 LCPs) have been proposed as protective against dementia and age related cognitive impairment.
Dangour, Alan +5 more
core +1 more source
Biosynthesis of food constituents: Lipids. 1. Fatty acids and derivated compounds - a review
This review article gives a survey of the principal biosynthetic pathways that lead to the most important common fatty acids and their derivatives occurring in foods and feeds.
Jan Velíšek, Karel Cejpek
doaj +1 more source
Resolution pharmacology is an emerging strategy to tackle inflammatory pathologies. Bioinspired meroterpenoids induce a lipid mediator class switch toward inflammation resolution in vitro and in vivo by targeting key nodes in lipid mediator biosynthesis and neutral lipid dynamics.
Lorenz Waltl +20 more
wiley +1 more source
Efficient and specific analysis of red blood cell glycerophospholipid fatty acid composition. [PDF]
Red blood cell (RBC) n-3 fatty acid status is related to various health outcomes. Accepted biological markers for the fatty acid status determination are RBC phospholipids, phosphatidylcholine, and phosphatidyletholamine.
Hans Demmelmair +11 more
core +2 more sources
Evidence for in situ ethanolamine phospholipid adducts with hydroxy-alkenals
Hydroxy-alkenals, such as 4-hydroxy-2(E)-nonenal (4-HNE; from n-6 fatty acids), are degradation products of fatty acid hydroperoxides, including those generated by free radical attack of membrane polyunsaturated fatty acyl moieties. The cytotoxic effects
Sandrine Bacot +7 more
doaj +1 more source
Metabolic Memory in Cardiovascular Disease: Encoding, Propagation, and Therapeutic Targeting
Cardiovascular risk often persists after metabolic abnormalities are corrected. This conceptual Review frames such persistence as metabolic memory, encoded through a narrowing therapeutic window from reversible marks to irreversible damage, with continuous input from peripheral organs.
Cheng Cheng +12 more
wiley +1 more source
Effects of dietary long-chain polyunsaturated fatty acids on plasma amino acids and indices of protein metabolism in infants: Results from a randomized clinical trial [PDF]
Background/Aim: Previous studies in vitro and in animals in vivo found that alpha-linolenic acid (C18:3 omega 3) may enhance oxidative damage of essential amino acids.
Burus, I. +2 more
core +1 more source

