Results 91 to 100 of about 285 (209)
Systems Genetics and Transcriptomics of Feed Efficiency in Dairy Cattle [PDF]
, 2015 Feed is the largest variable cost in milk production industries, thus improving feed efficiency will give better use of resources. This project works closely on definitions of feed efficiency in dairy cattle and uses advanced integrated genomics ...
Hoglund, J. +3 more
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Diabetic Medicine, EarlyView.Abstract Aims Managing diabetes during exercise remains challenging, particularly in settings of sustained physical activity such as diabetes‐camps. This study aimed to evaluate the efficacy and safety of a diabetes‐camp protocol including an adaptive algorithm for prandial bolus reduction and the use of automated insulin delivery (AID) exercise modes ...
Alzbeta Santova +12 more
wiley +1 more source
Hypoglycaemia care: Time to modernise our treatment standards
Diabetic Medicine, EarlyView.This editorial argues that hypoglycaemia self care should move beyond ‘any sugar will do’ and define what good recovery after treatment should involve. It proposes recovery‐focused standards using CGM metrics, such as time‐in‐range and repeat lows after treatment, alongside participant‐reported recovery, so existing and emerging approaches, including ...
David Russell‐Jones, Julia K. Mader
wiley +1 more source
Dapagliflozin Alters Plasma Metabolome in Patients With Type 1 Diabetes During Ketosis
Diabetes, Obesity and Metabolism, EarlyView.ABSTRACT Aims Use of sodium‐glucose cotransporter 2 inhibitors (SGLT2i) in patients with type 1 diabetes (T1D) is limited by increased risk of ketoacidosis. We aimed to determine metabolic pathways affected by SGLT2i treatment in adults with T1D during ketosis induced by insulin withdrawal.
Rosa Yang +6 more
wiley +1 more source
Physiological media and oxygen levels modulate cancer hallmarks in cultured breast cancer cells
The FEBS Journal, EarlyView.MCF7 breast cancer cells were cultured in standard conditions (18% O2 and DMEM) and physiological conditions (5% O2 and Plasmax, a medium modeled after the human plasma metabolome). A combined transcriptomic and proteomic approach was used to identify gene expression signatures at the mRNA and protein levels upstream of functional enrichment analyses ...
Jacob E. Wiebe +5 more
wiley +1 more source
The FEBS Journal, EarlyView.The microbial degradation of synthetic polyesters such as polyethylene terephthalate (PET) is mediated by diverse α/β‐hydrolases, many of which remain poorly characterized. In this study, we investigated the α/β‐hydrolase SM0281 from Sinorhizobium meliloti and found that it exhibits robust carboxylesterase and polyesterase activities toward PET, PCL ...
Sofia Lemak +7 more
wiley +1 more source
HIV Medicine, EarlyView.Abstract Objectives This national cross‐sectional observational study aimed to assess mental health, quality of life, supportive network, experiences of HIV‐related stigma in healthcare and unmet service need among trans and gender‐diverse people with HIV, compared to cisgender people with HIV.
H. Kitt +19 more
wiley +1 more source
Alteration of subgingival microbiome in patients with type 2 diabetes induced by diabetes treatment
Journal of Diabetes Investigation, EarlyView.ABSTRACT Aims/Introduction Diabetes and periodontal disease, a bacterial infection involving the oral microbiome, have a bidirectional relationship. However, the relationship between poor glycemic control and the oral microbiome remains unclear. The aim of this study was to assess the direct effect of intensive glycemic control on the oral microbiome ...
Moe Inoue +13 more
wiley +1 more source