Results 101 to 110 of about 1,972 (243)
Diabetic Medicine, EarlyView.Abstract Aims Managing diabetes during exercise remains challenging, particularly in settings of sustained physical activity such as diabetes‐camps. This study aimed to evaluate the efficacy and safety of a diabetes‐camp protocol including an adaptive algorithm for prandial bolus reduction and the use of automated insulin delivery (AID) exercise modes ...
Alzbeta Santova +12 more
wiley +1 more source
Hypoglycaemia care: Time to modernise our treatment standards
Diabetic Medicine, EarlyView.This editorial argues that hypoglycaemia self care should move beyond ‘any sugar will do’ and define what good recovery after treatment should involve. It proposes recovery‐focused standards using CGM metrics, such as time‐in‐range and repeat lows after treatment, alongside participant‐reported recovery, so existing and emerging approaches, including ...
David Russell‐Jones, Julia K. Mader
wiley +1 more source
Diabetes, Obesity and Metabolism, EarlyView.ABSTRACT Aims Survodutide is a novel long‐acting dual glucagon (GCGR)/glucagon‐like peptide‐1 (GLP‐1R) receptor agonist currently in phase‐3 clinical development for the treatment of people living with obesity and metabolic dysfunction‐associated steatohepatitis.
Alexander Hamilton +11 more
wiley +1 more source
Dapagliflozin Alters Plasma Metabolome in Patients With Type 1 Diabetes During Ketosis
Diabetes, Obesity and Metabolism, EarlyView.ABSTRACT Aims Use of sodium‐glucose cotransporter 2 inhibitors (SGLT2i) in patients with type 1 diabetes (T1D) is limited by increased risk of ketoacidosis. We aimed to determine metabolic pathways affected by SGLT2i treatment in adults with T1D during ketosis induced by insulin withdrawal.
Rosa Yang +6 more
wiley +1 more source
GLP‐1–Based Therapy in Type 1 Diabetes: Balancing Efficacy, Safety, and Patient Selection
Diabetes, Obesity and Metabolism, EarlyView.ABSTRACT Aims To critically examine the evolving evidence on glucagon‐like peptide‐1 receptor agonists (GLP‐1RAs) and the dual glucose‐dependent insulinotropic polypeptide (GIP)/GLP‐1 receptor agonist tirzepatide as adjuncts to insulin therapy in type 1 diabetes (T1D), with particular emphasis on their benefit–risk balance in individuals with ...
Thales Rossatto +2 more
wiley +1 more source
Microbiome-related metabolites in early to midpregnancy and risk of fetal growth extremes: a metabolome-wide association study. [PDF]
Am J Clin NutrZhu Y +9 more
europepmc +1 more source
Physiological media and oxygen levels modulate cancer hallmarks in cultured breast cancer cells
The FEBS Journal, EarlyView.MCF7 breast cancer cells were cultured in standard conditions (18% O2 and DMEM) and physiological conditions (5% O2 and Plasmax, a medium modeled after the human plasma metabolome). A combined transcriptomic and proteomic approach was used to identify gene expression signatures at the mRNA and protein levels upstream of functional enrichment analyses ...
Jacob E. Wiebe +5 more
wiley +1 more source
Controlling the Properties of Poly(3-hydroxybutyrate) through Lignin-Containing Organogels. [PDF]
BiomacromoleculesAlexakis AE +3 more
europepmc +1 more source