Results 121 to 130 of about 285 (209)

α‐Hydroxybutyrate Association With Incident Type 2 Diabetes Over 10 Years Across Different Glycemic States

open access: yesDiabetes, Obesity and Metabolism, Volume 28, Issue 10, Page 9493-9504, October 2026.
ABSTRACT Aim To investigate the association between baseline plasma α‐hydroxybutyrate (α‐HB), an organic acid derived from aminoacid catabolism and glutathione anabolism, and the 10‐year incidence of Type 2 diabetes (T2DM). Materials and Methods This prospective study analysed 1349 participants from the Swedish PAROKRANK study.
Elena Fortin   +5 more
wiley   +1 more source

P.8.007 The biotechnological production of potential neuroprotectants: oligo-3-hydroxybutyrates

open access: yes, 2011
A.P. Bonartsev   +4 more
core   +1 more source

Sleep Improvement for Metabolic Health: A Feasibility Trial of a Digital Sleep Treatment in People With Insomnia and Non‐Diabetic Hyperglycaemia

open access: yesJournal of Sleep Research, Volume 35, Issue 5, October 2026.
ABSTRACT Insomnia may play a causal role in type 2 diabetes (T2D). Addressing insomnia through cognitive behavioural therapy (CBTi) in people with non‐diabetic hyperglycaemia could potentially reduce the risk of progression to T2D. To inform a future randomised trial, we performed a feasibility study of digital CBT (dCBTi) in individuals at increased ...
Rachel Sharman   +11 more
wiley   +1 more source

Designing PLA/PHBV Implants With Degradation Matched to Normal or Inflammatory Tissues

open access: yesJournal of Applied Polymer Science, Volume 143, Issue 36, September 20, 2026.
PLA/PHBV blends are investigated under simulated normal and pathological conditions. Multivariate statistical analysis decouples the competing effects of water‐uptake‐driven hydrolysis and crystallinity‐imposed barriers. Melt‐state rheological parameters serve as structural probes linking phase morphology to degradation kinetics. A semi‐empirical model
Luyao Gao   +2 more
wiley   +1 more source

Additives Enhancing Biodegradability in Plastics and Potential Implications for Textiles: A Mechanistic Review

open access: yesJournal of Applied Polymer Science, Volume 143, Issue 35, September 15, 2026.
Mechanistic insights from additive‐assisted plastic degradation guide the design of environmentally adaptive textile fibers. Functional additives enhance oxidative, hydrolytic, enzymatic, and microbial degradation pathways. Translating these strategies requires control of fiber architecture, additive distribution, and environmental interactions ...
Julia Cunniffe   +2 more
wiley   +1 more source

Low Carbohydrate Availability in Energy Balance Alters Bone Turnover and Muscle Proteomic Response With Limited Endocrine Disruption

open access: yesThe FASEB Journal, Volume 40, Issue 17, 15 September 2026.
Eight trained males completed 4 days of normal‐carbohydrate or low‐carbohydrate (81% reduction in carbohydrate) diets while maintaining energy balance and undertaking daily exercise. Low carbohydrate decreased total body water and fat‐free mass, increased circulating free fatty acids, glycerol and β‐hydroxybutyrate, alongside increased fat oxidation at
Erick Mosquera‐Lopez   +8 more
wiley   +1 more source

Fenofibrate Protects Against Antipsychotic‐Induced Hyperglycemia Through Weight Loss and FGF21 Dependent Mechanisms

open access: yesThe FASEB Journal, Volume 40, Issue 17, 15 September 2026.
The proposed mechanism through which fenofibrate protects against olanzapine‐induced hyperglycemia in mice. ABSTRACT Antipsychotic (AP) medications, such as olanzapine, cause acute weight gain independent of hyperglycemia through a glucagon‐dependent mechanism.
Michael Akcan   +11 more
wiley   +1 more source

Bifidobacterium Pseudolongum‐Derived Inosine Mitigates Polystyrene Nanoplastics‐Induced Hepatic Injury by Inhibiting the Polarization of M1 Macrophages

open access: yesAdvanced Science, Volume 13, Issue 54, 28 September 2026.
Probiotic B.p colonization elevated gut‐derived inosine level in the liver, while elevated inosine activated A2AR and subsequently blocked NPs‐induced polarization of M1 macrophages by repressing the miR155/SOCS1/NF‐κB pathway. This reduced the release of inflammatory cytokines and thereby, mitigated NPs‐induced hepatic injury.
Kaikai Zhang   +10 more
wiley   +1 more source

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