Results 111 to 120 of about 1,972 (243)

Crystal structure and biochemical analysis of the polyester‐degrading carboxylesterase SM0281 from the symbiotic legume‐associated rhizobacterium Sinorhizobium (Ensifer) meliloti

The FEBS Journal, EarlyView.
The microbial degradation of synthetic polyesters such as polyethylene terephthalate (PET) is mediated by diverse α/β‐hydrolases, many of which remain poorly characterized. In this study, we investigated the α/β‐hydrolase SM0281 from Sinorhizobium meliloti and found that it exhibits robust carboxylesterase and polyesterase activities toward PET, PCL ...
Sofia Lemak, Anna N. Khusnutdinova, Peter J. Stogios, Elena Evdokimova, Alexei Savchenko, Peter N. Golyshin, Elizabeth A. Edwards, Alexander F. Yakunin   +7 more
wiley   +1 more source

The efficacy of disease-modifying therapies in patients with clinically isolated syndrome: a systematic review and network meta-analysis. [PDF]

Sci Rep
Chumpangern Y, Seawsirikul Y, Keatbundit P, Thongtem L, Uawithya E, Khampang R, Ongphichetmetha T, Siritho S, Prayoonwiwat N, Jitprapaikulsan J.   +9 more
europepmc   +1 more source

Wellbeing of trans and gender‐diverse people with HIV in the United Kingdom: Results from Positive Voices 2022

HIV Medicine, EarlyView.
Abstract Objectives This national cross‐sectional observational study aimed to assess mental health, quality of life, supportive network, experiences of HIV‐related stigma in healthcare and unmet service need among trans and gender‐diverse people with HIV, compared to cisgender people with HIV.
H. Kitt, C. Kelly, A. Aghaizu, M. Ross, F. C. Lampe, C. J. Smith, V. Martin, C. Humphreys, A. Brown, A. Sparrowhawk, M. Kall, J. Sewell, E. Wainwright, V. Delpech, G. Davis, A. Farah, A. Fasanya, A. J. Rodger, T. Đuretić, PV2022 Study Group   +19 more
wiley   +1 more source

<i>N</i>, <i>N</i>-Dimethyl-4-Aminopyridine- and Aluminum Isopropoxide-Catalysed Ring-Opening Polymerizations of <i>β</i>-Butyrolactone for the Antimicrobial Oligohydroxybutyrate. [PDF]

Int J Mol Sci
Bao Q, So PK, Leung SL, Leung PH, Tao X.
europepmc   +1 more source

Same‐night PrEP in community care: The Nightcafé model for male and transgender sex workers

HIV Medicine, EarlyView.
Abstract Introduction Despite high risk of HIV infection, uptake of pre‐exposure prophylaxis (PrEP) remains limited among male and transgender sex workers (MSW and TSW), and data on tailored interventions to improve access are scarce. The Nightcafé programme addresses this gap by offering low‐threshold PrEP provision in a community‐centred setting ...
Elena Heizmann, Andrea Farnham, Christian Grolimund, Jorge Flores Real, Paul Halm, Veronika Braig, Hadrien Komaromi, Giulietta Mila Laffers, Jan Fehr, Benjamin Hampel   +9 more
wiley   +1 more source

PCDA-EDA Colorimetric Nanofiber Sensor for Rapid Visual GHB Screening: Linker Reassignment and Scalable Fabrication. [PDF]

Biosensors (Basel)
Yang S, Lee J, Darlami O, Shin D.
europepmc   +1 more source

Antibacterial ZnO nanoparticle embedded polycaprolactone-polyhydroxybutyrate membranes for wound healing. [PDF]

J Mater Sci Mater Med
Sam S, Joseph B, Ninan N, Alemie MN, Vasilev K, Bright R, Thomas S.   +6 more
europepmc   +1 more source

Narcolepsy and rapid eye movement sleep

Journal of Sleep Research, Volume 34, Issue 2, April 2025.
Summary Since the first description of narcolepsy at the end of the 19th Century, great progress has been made. The disease is nowadays distinguished as narcolepsy type 1 and type 2. In the 1960s, the discovery of rapid eye movement sleep at sleep onset led to improved understanding of core sleep‐related disease symptoms of the disease (excessive ...
Francesco Biscarini, Lucie Barateau, Fabio Pizza, Giuseppe Plazzi, Yves Dauvilliers   +4 more
wiley   +1 more source

Genetic Influences on Disease-Modifying Therapy Response in Multiple Sclerosis: Current Insights and Future Directions. [PDF]

Balkan Med J
Reda MD, Siva A, Tahir Turanlı E.
europepmc   +1 more source

Sodium Oxybate Alters Sleep Architecture and Reduces Emotional Selectivity in Memory‐Related Responses

Journal of Sleep Research, EarlyView.
ABSTRACT Sleep supports memory consolidation. Non‐rapid eye movement (NREM) and rapid eye movement (REM) sleep have been proposed to support, respectively, declarative memory consolidation and the integration of the memory affective dimension. Here, we used sodium oxybate (SXB) to modify the NREM/REM proportion during one sleep night and assessed ...
Laure Colin, Kinga Igloi, Alison Montagrin, Samika Kumar, Jeremy Hofmeister, Markus Gschwind, Sophie Schwartz, Virginie Sterpenich   +7 more
wiley   +1 more source