Hydroxychloroquine-induced Retinal Toxicity
Long-term use of hydroxychloroquine can cause retinopathy, which may result in severe and progressive visual loss. In the past decade, hydroxychloroquine use has markedly increased and modern retinal imaging techniques have enabled the detection of early,
Imran H. Yusuf +2 more
doaj +2 more sources
Lopinavir-ritonavir versus hydroxychloroquine for viral clearance and clinical improvement in patients with mild to moderate coronavirus disease 2019 [PDF]
Background/Aims The efficacies of lopinavir-ritonavir or hydroxychloroquine remain to be determined in patients with coronavirus disease 2019 (COVID-19).
Ji-Won Kim +6 more
doaj +1 more source
BackgroundHydroxychloroquine is not efficacious as post-exposure prophylaxis against coronavirus disease 2019 (COVID-19). It is not known whether as pre-exposure prophylaxis it may prevent COVID-19.ObjectiveTo compare the incidence of COVID-19 in Spanish
Juan Macías +11 more
doaj +1 more source
New Benefits of Hydroxychloroquine in Pregnant Women with Systemic Lupus Erythematosus: A Retrospective Study in a Tertiary Centre [PDF]
Objective: To determine pregnancy outcomes in women with systemic lupus erythematosus (SLE) who were treated with hydroxychloroquine in a tertiary center.
Rahana Abd Rahman +5 more
doaj +1 more source
The mechanism of chloroquine/hydroxychloroquine and its application in stomatological diseases
Chloroquine and hydroxychloroquine are both classic 4-aminoquinoline antimalarial drugs with similar chemical structures and mechanisms of action.
LIN Lin, WU Kaihui, WANG Wenmei
doaj +1 more source
Hydroxychloroquine retinopathy [PDF]
Hydroxychloroquine (HCQ; Plaquenil) is used increasingly in the management of a variety of autoimmune disorders, with well established roles in dermatology and rheumatology and emerging roles in oncology. Hydroxychloroquine has demonstrated a survival benefit in patients with systemic lupus erythematosus; some clinicians advocate its use in all such ...
Yusuf, I +3 more
openaire +2 more sources
Hydroxychloroquine Blood Levels Predict Hydroxychloroquine Retinopathy
ObjectiveIn 2016, the American Academy of Ophthalmology (AAO) changed the recommended daily dose of hydroxychloroquine (HCQ) from 6.5 mg/kg to <5 mg/kg. However, it is not clear that the lower prescribed dose of HCQ will have the same efficacy for systemic lupus erythematosus (SLE) activity or the same role in protecting against cardiovascular risk ...
Michelle Petri +4 more
openaire +3 more sources
Hyperpigmentation Induced by Hydroxychloroquine: A Case Report [PDF]
Hydroxychloroquine is an antimalarial drug which is widely used in the treatment of rheumatoid arthritis, owing to its immunosuppressive and anti-inflammatory properties.
Bhanukumar Muthaiah +2 more
doaj +1 more source
Cytokine release syndrome in COVID-19 patients, a new scenario for an old concern. The fragile balance between infections and autoimmunity [PDF]
On 7 January 2020, researchers isolated and sequenced in China from patients with severe pneumonitis a novel coronavirus, then called SARS-CoV-2, which rapidly spread worldwide, becoming a global health emergency.
Diamanti, A. P. +4 more
core +2 more sources

