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Hydroxychloroquine and Cardiotoxicity
Cardiology in Review, 2023Hydroxychloroquine (HCQ) has been used for rheumatological diseases such as systemic lupus erythematous and rheumatoid arthritis and demonstrated to improve clinical symptoms and reduce long-term sequelae. The drug is metabolized in the liver, is primarily excreted through the kidney, and works by modulating major histocompatibility complex (MHC) and ...
Subo, Dey +6 more
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Hydroxychloroquine and the Retina
JAMA, 2015Hydroxychloroquine sulfate is widely prescribed in the treatment of systemic lupuserythematosus (SLE), rheumatoidarthritis, and related autoimmunediseases, and it has largely superseded the use of chloroquinephosphate for these conditions. Furthermore, hydroxychloroquine isnowbeingevaluated forothermedical uses, including controlofbloodglucose ...
Michael F, Marmor, Ronald B, Melles
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Hydroxychloroquine Retinopathy
American Journal of Ophthalmology, 1991We analyzed ocular findings from two patients (aged 49 and 60 years) with hydroxychloroquine (Plaquenil, Winthrop Pharmaceuticals, Division of Sterling Drug, Inc., New York, New York) retinopathy. Both patients were treated for systemic lupus erythematosus; one patient was treated with 400 to 800 mg of hydroxychloroquine per day (6.1 to 12.2 mg/kg of ...
A, Weiner +4 more
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Archives of Ophthalmology, 1982
To the Editor. —The article by Tobin et al published in the JanuaryArchives(1982;100:81-83) on the safety of hydroxychloroquine sulfate recalls my experience with this drug in rheumatic diseases. During the past 15 years, I have followed up approximately 100 patients with rheumatoid arthritis and lupus erythematosus who were given hydroxychloroquine ...
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To the Editor. —The article by Tobin et al published in the JanuaryArchives(1982;100:81-83) on the safety of hydroxychloroquine sulfate recalls my experience with this drug in rheumatic diseases. During the past 15 years, I have followed up approximately 100 patients with rheumatoid arthritis and lupus erythematosus who were given hydroxychloroquine ...
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Agranulocytosis and Hydroxychloroquine
New England Journal of Medicine, 1967R P, Propp, J S, Stillman
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