Results 31 to 40 of about 115,105 (360)

Hydroxychloroquine for chronic myeloid leukemia: complete cure on the horizon? [PDF]

, 2011
No abstract ...
Amaravadi, Arunima Mukhopadhyay, Bellodi, Belloni, Boya, Druker, Furst, Gordon, Gozuacik, Gudmundur V Helgason, Jiang, Kalia, Kim, Maria Karvela, Munster, Naka, Ozvegy-Laczka, Savarino, Sharma, Tessa L Holyoake, Zaidi   +20 more
core   +1 more source

CD4 T lymphocyte autophagy is upregulated in the salivary glands of primary Sjögren’s syndrome patients and correlates with focus score and disease activity [PDF]

, 2017
Background: Primary Sjögren’s syndrome (pSS) is a common chronic autoimmune disease characterized by lymphocytic infiltration of exocrine glands and peripheral lymphocyte perturbation.
A Bhattacharya, AG Tzioufas, Annacarla Finucci, Antonina Minniti, Aroldo Rizzo, C Alessandri, C Li, C Vitali, C Vitali, CQ Nguyen, Cristiana Barbati, Cristiano Alessandri, D Geem, DJ Klionsky, DM Chisholm, E Astorri, Elena Ortona, Elisa Astorri, F Barone, F Ciccia, F Ciccia, F Ciccia, F Ciccia, F Sallusto, Fabrizio Conti, Francesco Ciccia, Giovanni Triolo, Giuliana Guggino, Guido Valesini, H Nakatogawa, HH Pua, HH Pua, HH Pua, I Tanida, LM Gerland, M Bombardieri, M Bombardieri, M Morgan-Bathke, M Morgan-Bathke, M Moriyama, M Pierdominici, Marina Pierdominici, Marta Vomero, Monica Pendolino, N Mizushima, N Schmitt, R Seror, Riccardo Alessandro, Roberta Priori, S Katsiougiannis, S Romao, Tania Colasanti, TC Adamson 3rd, W Jia, Walter Malorni, XJ Zhou, Y Seo, YZ Gong, Z Yang   +58 more
core   +3 more sources

Effect of Hydroxychloroquine on Clinical Status at 14 Days in Hospitalized Patients With COVID-19: A Randomized Clinical Trial.

Journal of the American Medical Association (JAMA), 2020
Importance Data on the efficacy of hydroxychloroquine for the treatment of coronavirus disease 2019 (COVID-19) are needed. Objective To determine whether hydroxychloroquine is an efficacious treatment for adults hospitalized with COVID-19.
W. Self, M. Semler, Lindsay M. Leither, J. Casey, D. Angus, R. Brower, Steven Y. Chang, S. Collins, John Eppensteiner, M. Filbin, D. Files, K. Gibbs, A. Ginde, M. Gong, F. Harrell, Douglas L. Hayden, C. Hough, N. Johnson, Akram Khan, C. Lindsell, M. Matthay, M. Moss, P. Park, T. Rice, B. Robinson, D. Schoenfeld, N. Shapiro, J. Steingrub, C. Ulysse, A. Weissman, D. Yealy, B. Thompson, Samuel M. Brown   +32 more
semanticscholar   +1 more source

Hydroxychloroquine reduces soluble Flt-1 secretion from human cytotrophoblast, but does not mitigate markers of endothelial dysfunction in vitro.

PLoS ONE, 2022
Preeclampsia is a multi-system disease that can have severe, even fatal implications for the mother and fetus. Abnormal placentation can lead to ischaemic tissue injury and placental inflammation.
Elif Kadife, Natalie Hannan, Alesia Harper, Natalie Binder, Sally Beard, Fiona C Brownfoot   +5 more
doaj   +2 more sources

IgG anti-apolipoprotein A-1 antibodies in patients with systemic lupus erythematosus are associated with disease activity and corticosteroid therapy: an observational study. [PDF]

, 2015
IgG anti-apolipoprotein A-1 (IgG anti-apoA-1) antibodies are present in patients with systemic lupus erythematosus (SLE) and may link inflammatory disease activity and the increased risk of developing atherosclerosis and cardiovascular disease (CVD) in ...
Alber, KF, Bassett, P, Chambers, S, Croca, S, Davari, M, Giles, I, Ioannou, Y, Isenberg, D, Leach, O, Rahman, A   +9 more
core   +1 more source

Mortality outcomes with hydroxychloroquine and chloroquine in COVID-19 from an international collaborative meta-analysis of randomized trials

Nature Communications, 2021
Substantial COVID-19 research investment has been allocated to randomized clinical trials (RCTs) on hydroxychloroquine/chloroquine, which currently face recruitment challenges or early discontinuation. We aim to estimate the effects of hydroxychloroquine
C. Axfors, A. Schmitt, P. Janiaud, J. van’t Hooft, S. Abd-Elsalam, Ehab F. Abdo, B. Abella, J. Akram, R. Amaravadi, D. Angus, Y. Arabi, Shehnoor Azhar, L. Baden, A. Baker, L. Belkhir, T. Benfield, M. Berrevoets, Cheng-Pin Chen, Tsung-Chia Chen, Shu-Hsing Cheng, Chien-Yu Cheng, W. Chung, Yehuda Z. Cohen, Lisa N. Cowan, O. Dalgard, F. F. de Almeida e Val, M. V. D. de Lacerda, G. D. de Melo, L. Derde, V. Dubée, A. Elfakir, A. Gordon, C. Hernández-Cárdenas, T. Hills, A. Hoepelman, Yi-Wen Huang, B. Igau, R. Jin, Felipe Jurado-Camacho, K. Khan, P. Kremsner, B. Kreuels, Cheng-yu Kuo, Thuy-Tien C. Le, Yi-Chun Lin, Wu-Pu Lin, Tse-Hung Lin, M. Lyngbakken, C. McArthur, B. McVerry, Patricia A Meza-Meneses, W. Monteiro, S. Morpeth, Ahmad Mourad, M. Mulligan, S. Murthy, S. Naggie, S. Narayanasamy, A. Nichol, L. Novack, Sean M. O'Brien, N. Okeke, L. Perez, R. Perez-Padilla, L. Perrin, A. Remigio-Luna, N. Rivera-Martínez, F. Rockhold, S. Rodríguez-Llamazares, R. Rolfe, Rossana Rosa, H. Røsjø, V. Sampaio, T. Seto, Muhammad Shahzad, S. Soliman, J. Stout, Ireri Thirión-Romero, A. Troxel, Ting-Yu Tseng, N. Turner, Robert J. Ulrich, S. Walsh, S. Webb, Jesper M. Weehuizen, M. Velinova, Hon-Lai Wong, R. Wrenn, F. Zampieri, Wu Zhong, D. Moher, S. N. Goodman, J. Ioannidis, L. Hemkens   +93 more
semanticscholar   +1 more source

The effect of hydroxychloroquine on glucose control and insulin resistance in the prediabetes condition

Advanced Biomedical Research, 2016
Background: Hydroxychloroquine can improve most underlying coronary risk factors; however, there are a few studies on the effects of hydroxychloroquine on blood glucose and insulin resistance.
Fahimeh Sheikhbahaie, Masoud Amini, Mojgan Gharipour, Ashraf Aminoroaya, Nader Taheri   +4 more
doaj   +1 more source

How different is the status of depression and anxiety in patients with rheumatoid arthritis receiving methotrexate with sulfasalazine or hydroxychloroquine?

Russian Open Medical Journal, 2023
Background — Depression and anxiety are among the most common clinical manifestations in patients with rheumatoid arthritis (RA). Sulfasalazine and hydroxychloroquine are important medications used to treat these patients.
Mansour Babaei, Mehdi Dorparvar, Behnaz Yousef Ghahari, Behzad Heidari, Hemmat Gholinia, Sussan Moudi   +5 more
doaj   +1 more source

Association of hydroxychloroquine and cardiac arrhythmia in patients with systemic lupus erythematosus: A population-based case control study.

PLoS ONE, 2021
ObjectivesHydroxychloroquine is widely used to treat certain viral and rheumatic diseases including systemic lupus erythematosus. Cardiac arrhythmia is an important safety issue with hydroxychloroquine.
Chien-Hsien Lo, Yu-Hsun Wang, Chin-Feng Tsai, Kuei-Chuan Chan, Li-Ching Li, Tse-Hsien Lo, James Cheng-Chung Wei, Chun-Hung Su   +7 more
doaj   +1 more source

Are bisphosphonates effective in the treatment of osteoarthritis pain? A meta-analysis and systematic review. [PDF]

, 2013
Osteoarthritis (OA) is the most common form of arthritis worldwide. Pain and reduced function are the main symptoms in this prevalent disease. There are currently no treatments for OA that modify disease progression; therefore analgesic drugs and joint ...
AD Beswick, Alison J. Davis, AM Lievense, Caroline B. Hing, CO Bingham, D Moher, DA Walsh, DA Walsh, DJ Hunter, E Yusuf, G Saviola, GA Rodan, IK Haugen, JC Buckland-Wright, KA Reilly, LD Carbone, LL Laslett, M Jokar, M Moreau, M Rossini, M Sato, M van Tulder, MC Jensen, N Bellamy, N Sofat, Nidhi Sofat, Sam Eldabe, T Fujita, T Fujita, T Fujita, T Fujita, T Kawasaki, T Nishii, T Yoneda, TD Spector, TO Smith, Toby O. Smith, UA Liberman   +37 more
core   +3 more sources