Results 91 to 100 of about 512 (119)

1alpha hydroxycholecalciferol in the prevention of milk fever

Veterinary Record, 1978
During the 12 months commencing July 1976 the animals in a herd of 400 Friesian cows which were carrying their second or later calf were injected intramuscularly with either microgram of 1alpha-hydroxycholecalciferol in 5 ml aqueous carrier or with 5 ml of carrier.
F G, Wittwer, E J, Ford
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25-Hydroxycholecalciferol levels in bedouins in the Negev

The American Journal of Clinical Nutrition, 1976
25-Hydroxycholecalciferol (25-HCC) levels were measured in 31 bedouin females and eight bedouin male tribesmen and compared with the levels in Jewish males and females in Beersheba. In nonpregnant bedouin women the mean 25-HCC level was 25.4 ng/ml +/- 9.78. In pregnant bedouin women the mean was 23.4 ng/ml +/- 8.52.
S, Shany, J, Hirsh, G M, Berlyne
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1 alpha hydroxycholecalciferol and 25 hydroxycholecalciferol in renal bone disease.

Proceedings of the European Dialysis and Transplant Association. European Dialysis and Transplant Association, 1976
Four microgrammes of 1-alpha-hydroxycholecalciferol (1-alpha-OH D3) or 200 mug of 25-hydroxycholecalciferol (25-OH D3) were given orally every other day respectively to 10 uraemic patients (8 on chronic haemodialysis) for 1-12 weeks and to 3 patients on chronic haemodialysis for 4-8 weeks.
A E, Fournier, P J, Bordier, J, Gueris, J, Chanard, P, Marie, C, Ferriere, M, Osario, J, Bedrossian, H F, De Luca   +8 more
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Metabolism of 25-Hydroxycholecalciferol in Nephrectomized Rats

Klinische Wochenschrift, 1971
Der Metabolismus von 25-Hydroxycholecalciferol wurde in nephrektomierten rachitischen Ratten und in rachitischen Kontroll-Ratten untersucht. Das Stoffwechselmuster war fur beide Gruppen in Blut, Knochen, Leber und in der Darmschleimhaut ahnlich. Insbesondere war auch die Bildung von Peak V, der als ein aktiver Metabolit von Vitamin D angesehen wird ...
K, Schaefer, D, von Herrath, H U, Koch, A, Opitz, R, Stratz   +4 more
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The Influence of Phenobarbital on Biotransformation of 25‐Hydroxycholecalciferol

The Journal of Clinical Pharmacology, 1976
Altered vitamin D metabolism has been implicated as a cause of anticonvulsant-induced osteomalacia. Previous studies have demonstrated accelerated biotransformation of vitamin D3 to 25-hydroxycholecalciferol (25-OHD3). However, it is not known whether the 25-OHD3 is metabolized to 1,25-dihydroxycholecalciferol (1,25-(OH)2D3), the tissue-active ...
R, Burt, J W, Freston, K G, Tolman
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Acute Administration of 25-Hydroxycholecalciferol in Man

The Journal of Clinical Endocrinology & Metabolism, 1976
Serum 25-hydroxyvitamin D responses to oral doses of 25-hydroxycholecalciferol were measured in healthy volunteers. Peak serum 25-hydroxyvitamin D levels occurred 4 to 8 hours after doses of 1.5, 5, and 10 mug per kg of body weight. The mean increments above baseline serum 25-hydroxyvitamin D concentrations at 4 hours were linear over this dose range ...
J G, Haddad, S, Rojanasathit
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25-Hydroxycholecalciferol Metabolism in Hypophysectomized Rats*

Endocrinology, 1978
The metabolism of 25-hydroxycholecalciferol (25-(OH)Da) was investigated in vitamin D normal rats, 4 weeks after hypophysectomy. Compared to sham-operated controls, these animals were hypophosphatemic and their parathyroid glands were significantly smaller than normal. Eighteen hours after ip injection of a single dose of tritiated 25-(OH)D3 (50 pmol),
O, Fontaine, H, Pavlovitch, S, Balsan
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Metabolism of 25-hydroxycholecalciferol by human bone

Journal of Endocrinological Investigation, 1983
Although there is abundant evidence from animal studies that 1,25-dihydroxychole-calciferol [1,25-(OH)2D3] is synthesized in the kidney, it is still unknown whether human bone might also be involved in the formation of this metabolite. To investigate whether 1,25-(OH)2D3 can be synthesized by human bone, 25-hydroxycholecalciferol (25-OH D3) metabolism ...
E, Keck, R, Durdel, T, West, F, Krück, W, Meier, U, Hennes, H L, Krüskemper, H U, Schweikert   +7 more
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Synthesis of [26,27-3H]-25-hydroxycholecalciferol

Analytical Biochemistry, 1971
Abstract [26,27- 3 H]-25-HCC has been chemically synthesized. This preparation is radiochemically pure and has a specific activity (180,000 dpm/IU, 1.3 Ci/mmole) high enough to permit experiments with 0.025 μg of 25-HCC/rat. This preparation is biologically as active (52 IU/μg) as either isolated or synthetic 25-HCC in curing rickets in rats.
T, Suda, H F, DeLuca, R B, Hallick
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1‐ALPHA‐HYDROXYCHOLECALCIFEROL IN THE TREATMENT OF HYPOCALCAEMIC PSYCHOSIS

Clinical Endocrinology, 1976
SUMMARYTwo patients with profound hypocalcaemia due to uraemia and hypopara‐thyroidism respectively presented with alterations of mental state as their dominant symptom. 1‐Alpha‐hydroxycholecalciferol (1‐α‐OHD3) was chosen as the principal therapy because of its potency and rapid action.
J M, Gertner, A B, Hodsman, J N, Neuberger   +2 more
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