Results 51 to 60 of about 80 (77)
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1 alpha hydroxycholecalciferol and 25 hydroxycholecalciferol in renal bone disease.
Proceedings of the European Dialysis and Transplant Association. European Dialysis and Transplant Association, 1976Four microgrammes of 1-alpha-hydroxycholecalciferol (1-alpha-OH D3) or 200 mug of 25-hydroxycholecalciferol (25-OH D3) were given orally every other day respectively to 10 uraemic patients (8 on chronic haemodialysis) for 1-12 weeks and to 3 patients on chronic haemodialysis for 4-8 weeks.
A E, Fournier +8 more
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1alpha hydroxycholecalciferol in the prevention of milk fever
Veterinary Record, 1978During the 12 months commencing July 1976 the animals in a herd of 400 Friesian cows which were carrying their second or later calf were injected intramuscularly with either microgram of 1alpha-hydroxycholecalciferol in 5 ml aqueous carrier or with 5 ml of carrier.
F G, Wittwer, E J, Ford
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The Influence of Phenobarbital on Biotransformation of 25‐Hydroxycholecalciferol
The Journal of Clinical Pharmacology, 1976Altered vitamin D metabolism has been implicated as a cause of anticonvulsant-induced osteomalacia. Previous studies have demonstrated accelerated biotransformation of vitamin D3 to 25-hydroxycholecalciferol (25-OHD3). However, it is not known whether the 25-OHD3 is metabolized to 1,25-dihydroxycholecalciferol (1,25-(OH)2D3), the tissue-active ...
R, Burt, J W, Freston, K G, Tolman
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Acute Administration of 25-Hydroxycholecalciferol in Man
The Journal of Clinical Endocrinology & Metabolism, 1976Serum 25-hydroxyvitamin D responses to oral doses of 25-hydroxycholecalciferol were measured in healthy volunteers. Peak serum 25-hydroxyvitamin D levels occurred 4 to 8 hours after doses of 1.5, 5, and 10 mug per kg of body weight. The mean increments above baseline serum 25-hydroxyvitamin D concentrations at 4 hours were linear over this dose range ...
J G, Haddad, S, Rojanasathit
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25-Hydroxycholecalciferol Metabolism in Hypophysectomized Rats*
Endocrinology, 1978The metabolism of 25-hydroxycholecalciferol (25-(OH)Da) was investigated in vitamin D normal rats, 4 weeks after hypophysectomy. Compared to sham-operated controls, these animals were hypophosphatemic and their parathyroid glands were significantly smaller than normal. Eighteen hours after ip injection of a single dose of tritiated 25-(OH)D3 (50 pmol),
O, Fontaine, H, Pavlovitch, S, Balsan
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TREATMENT OF OSTEOPOROSIS OF AGEING WITH 1α-HYDROXYCHOLECALCIFEROL
The Lancet, 1975Seven patients with osteoporosis of ageing were treated with synthetic 1alpha-hydroxycholecalciferol (1alpha-H.C.C.) for 3-4 months. The compound was given at a daily oral dose of 2 mug together with an oral supplement of 1 g of calcium. Clinically there was a striking improvement in the patients' physical fitness.
B, Lund +6 more
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Clinical Uses of 1-alpha-hydroxycholecalciferol
Current Vascular Pharmacology, 2014Alfacalcidol is a widely used vitamin D compound, especially in clinical nephrology because it does not require enzymatic activation by the kidneys. For that reason it has been used for decades to treat abnormalities in bone and mineral balance that arise in chronic kidney disease.
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The plasma transport proteins of 25-hydroxycholecalciferol in mammals
Comparative Biochemistry and Physiology Part B: Comparative Biochemistry, 1976Abstract 1. 1. The transport proteins of 25-hydroxycholecalciferol were studied in 72 species from 14 mammalian orders. 2. 2. Sixty-five species had an α-globulin transport protein. 3. 3. Seven species: Pacific Dolphin, Killer Whale, African Elephant, Indian Elephant, White-throated Capuchin (Monkey), White-fronted Capuchin and Brown ...
A W, Hay, G, Watson
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Synthesis of [26,27-3H]-25-hydroxycholecalciferol
Analytical Biochemistry, 1971Abstract [26,27- 3 H]-25-HCC has been chemically synthesized. This preparation is radiochemically pure and has a specific activity (180,000 dpm/IU, 1.3 Ci/mmole) high enough to permit experiments with 0.025 μg of 25-HCC/rat. This preparation is biologically as active (52 IU/μg) as either isolated or synthetic 25-HCC in curing rickets in rats.
T, Suda, H F, DeLuca, R B, Hallick
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1α-HYDROXYCHOLECALCIFEROL AND RENAL FUNCTION
The Lancet, 1978B, Lund, O H, Sørensen, B, Lund
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