Results 61 to 70 of about 6,185 (138)

Side-chain oxidized oxysterols as metabolic regulators in liver and brain

, 2014
Oxysterols are oxygenated derivatives of cholesterol characterized by a very short half-life and their ability to pass lipophilic membranes easily, thus they are considered as important intermediates in cholesterol excretion pathways and its conversion ...
Zeina Ali (18675067)
core   +1 more source

The analysis of oxysterols by capillary liquid chromatography tandem mass spectrometry

, 2009
Oxysterols are oxygenated metabolites of cholesterol. They are present in very low concentrations in mammalian systems, always accompanied by high excess of cholesterol. Therefore, their analysis can be challenging.
Karu, Kersti
core  

The Importance of "Negative" Results: Lipid Lessons in Coronavirus Biology. [PDF]

Am J Respir Cell Mol Biol, 2023
Leist SR, Mock JR.
europepmc   +1 more source

Reduced Membrane CD163 Expression in 7-Oxysterol-Induced Apoptosis Accompanied by Elevated Oxidative Stress. [PDF]

Cells
Li W, Yuan XM.
europepmc   +1 more source

Neutrophils exposed to a cholesterol metabolite secrete extracellular vesicles that promote epithelial-mesenchymal transition and stemness in breast cancer cells. [PDF]

Cancer Lett
Krawczynska N, Wang Y, Lim K, Das Gupta A, Molino RJEJ, Lenczowski A, Abughazaleh M, Bendre SV, Fei Y, Kim H, Kockaya LI, Schane CP, Pradeep D, Rodriguez-Casiano D, Hernandez AG, Drnevich J, Chan J, Dobrucki LW, Boppart MD, Cologna SM, Ostrander J, Nelson ER.   +21 more
europepmc   +1 more source

A Validated Mass Spectrometry Platform for Oxysterol Analysis of Single Human Gastruloids and Liver Organoids. [PDF]

Anal Chem
Kømurcu KS, Zawadzka ME, Meszka I, Aizenshtadt A, Hrušková H, Aakervik LE, Thorne JL, Wilson SR, Krauss SJK, Røberg-Larsen H.   +9 more
europepmc   +1 more source

Liver X Receptor α (LXRα) Regulates 5β-Reductase (AKR1D1) Expression in Avian Embryos: Implications for Yolk Steroid Metabolism. [PDF]

J Exp Zool A Ecol Integr Physiol
Paitz RT, Waters SE, Reynolds DK, Drew EM, Harders EP.   +4 more
europepmc   +1 more source

Endogenous and Therapeutic 25-Hydroxycholesterols May Worsen Early SARS-CoV-2 Pathogenesis in Mice. [PDF]

Am J Respir Cell Mol Biol, 2023
Fessler MB, Madenspacher JH, Baker PJ, Hilligan KL, Bohrer AC, Castro E, Meacham J, Chen SH, Johnson RF, McDonald JG, Martin NP, Tucker CJ, Mahapatra D, Cesta M, Mayer-Barber KD.   +14 more
europepmc   +1 more source

Utility of 24(S)-hydroxycholesterol as a proximal biomarker to monitor long-term intrathecal adrabetadex therapy in individuals with Niemann-Pick disease, type C1. [PDF]

Mol Genet Metab
Porter FD, Alexander DM, Albert OK, Robbins KP, Labor DA, Borruso AJ, Farhat NY, Jiang X, Berry-Kravis E.   +8 more
europepmc   +1 more source

Candidate-gene-based study of CYP3A-related single-nucleotide polymorphisms using 4β-hydroxycholesterol/cholesterol ratio as biomarker in a Japanese cohort. [PDF]

Eur J Clin Pharmacol
Tanaka R, Suzuki Y, Koyama T, Sumimoto T, Oda A, Sato H, Ozaki E, Tatsuta R, Yamamoto Y, Nakatochi M, Momozawa Y, Ohno K, Takashima N, Matsuo K, Itoh H.   +14 more
europepmc   +1 more source