Results 1 to 10 of about 2,824 (172)

Hydroxycitric acid ameliorates inflammation and oxidative stress in mouse models of multiple sclerosis [PDF]

Neural Regeneration Research, 2016
Hydroxycitric acid (HCA) is derived primarily from the Garcinia plant and is widely used for its anti-inflammatory effects. Multiple sclerosis can cause an inflammatory demyelination and axonal damage.
Mahdi Goudarzvand, Sanaz Afraei, Somaye Yaslianifard, Saleh Ghiasy, Ghazal Sadri, Mustafa Kalvandi, Tina Alinia, Ali Mohebbi, Reza Yazdani, Shahin Khadem Azarian, Abbas Mirshafiey, Gholamreza Azizi   +11 more
doaj   +5 more sources

Chickpea and soybean protein delivery systems for oral ingestion of hydroxycitric acid

Food Chemistry Advances, 2023
The plant derived product, hydroxycitric acid (HCA), extracted from the rind of Garcinia cambogia is a promising weight loss agent. Since HCA irritates the stomach and undergoes gastrointestinal degradation, encapsulation was carried out using two ...
I. Farrah Shakoor, Geethi K. Pamunuwa, D. Nedra Karunaratne   +2 more
doaj   +3 more sources

Plant Growth Inhibitory Activity of Hibiscus sabdariffa Calyx and the Phytotoxicity of Hydroxycitric Acid Lactone

Agronomy, 2023
Weeds pose major constraints in crop production. The use of allelochemicals and allelopathic species can provide an effective alternative for sustainable weed management. In a previous study that evaluated the allelopathic activity of wild and cultivated
Tugba Gonca Isin Ozkan, Kwame Sarpong Appiah, Emine Akalin, Yoshiharu Fujii   +3 more
doaj   +2 more sources

Production of Hydroxycitric Acid by Microorganisms

Bioscience, Biotechnology and Biochemistry, 2005
Hydroxycitric acid (HCA) is a major acid component of the tropical plants Garcinia cambogia and Hibiscus subdariffa. (2S,3S)-HCA from G. cambogia was shown to be a potent inhibitor of ATP citrate lyase (EC4.1.3.8), which catalyzes the extramitochondrial cleavage of citrate to oxaloacetate and acetyl-CoA. (2S,3R)-HCA from H.
HIDA, Hiroyuki, YAMADA, Takashi, YAMADA, Yasuhiro   +2 more
exaly   +5 more sources

Absolute Configuration of Hydroxycitric Acid Produced by Microorganisms

Bioscience, Biotechnology and Biochemistry, 2006
Optical resolution for (2S,3R) and (2R,3S)-hydroxycitric acid (HCA) enantiomers was developed using chiral column chromatography. HCA from Bacillus megaterium G45C and Streptomyces sp. U121, newly isolated in our previous study, was analyzed to determine the absolute configuration. These results indicate that both strains generate optically pure (2S,3R)
HIDA, Hiroyuki, YAMADA, Takashi, YAMADA, Yasuhiro   +2 more
exaly   +3 more sources

Metabolomics reveals the mechanism of (−)-hydroxycitric acid promotion of protein synthesis and inhibition of fatty acid synthesis in broiler chickens

Animal, 2018
(−)-Hydroxycitric acid (HCA), a major component of Garcinia cambogia extracts, has been shown to suppress BW gain and fat accumulation in animals and humans. However, the mechanism remains unknown.
M.L. Peng, J. Han, L.L. Li, H.T. Ma
doaj   +3 more sources

Isolation and Quantification of 2--Caffeoyl-hydroxycitric Acid, an Active Component in Hot Water Extracts of Coriander ( L.), Which Inhibits Degranulation of RBL-2H3 Cells

Natural Product Communications, 2023
Objectives: Natural compounds that can effectively prevent and alleviate allergic symptoms, such as hay fever, are widely sought after from sources such as natural ingredients that can be ingested daily. Coriander extracts have been reported to show anti-
Tsuyoshi Ikeda, Takuya Sugahara, Honoka Kanamitsu, Keisuke Nakashima, Hiroyuki Onda, Nanami Yoshino, Kosuke Nishi, Momoko Ishida   +7 more
doaj   +1 more source

Development of Oral In Situ Gelling Liquid Formulations of Garcinia Extract for Treating Obesity

Gels, 2023
Novel in situ gelling liquid formulations incorporating garcinia extract were developed to achieve prolonged delivery of hydroxycitric acid (HCA), an active compound displaying anti-obesity function, following oral administration.
Kantiya Fungfoung, Rachanida Praparatana, Ousanee Issarachot, Ruedeekorn Wiwattanapatapee   +3 more
doaj   +1 more source

Nutraceutical, functional, and therapeutic properties of Garcinia cambogia: a review

International Journal of Food Properties, 2023
Garcinia gummigutta, also known as Garcinia cambogia, has been shown to have excellent properties beneficial against many health conditions. The use of Garcinia cambogia in traditional medicine has involved treating gastrointestinal ailments, intestinal ...
Sana Noreen, Madiha Khan Naizi, Tabussam Tufail, Farooq Hassan, Chinaza Godswill Awuchi   +4 more
doaj   +1 more source

Molecular docking prediction and in vitro studies elucidate anti-inflammatory effect of Garcinia extract against inducible nitric oxide synthase and cyclooxygenase-2 targets

Beni-Suef University Journal of Basic and Applied Sciences, 2022
Background Garcinia is a tropical plant that has been traditionally used in medicinal folklore for its potential antioxidant, antibacterial, anti-hyperlipidemic, anti-diabetic, hepatoprotective, etc.
Anuradha Kalita, Manas Das, Bhabajyoti Das, Momita Rani Baro   +3 more
doaj   +1 more source