Results 1 to 10 of about 2,682 (120)

Hydroxycitric acid does not promote inflammation or liver toxicity. [PDF]

World J Gastroenterol, 2013
Garcinia cambogia extract (GC) with its active component consisting of hydroxycitric acid (HCA) is widely utilized for weight loss. Various HCA salts are available, including calcium, magnesium, potassium and mixtures of these. Experimentally, these salts exhibit different properties with some, but not all, improving glucose tolerance and blood ...
Clouatre DL, Preuss HG.
europepmc   +3 more sources

No evidence demonstrating hepatotoxicity associated with hydroxycitric acid. [PDF]

World J Gastroenterol, 2009
Although a number of cases of hepatotoxicity are associated with the use of Hydroxycut weight management products, it has been alleged that their effects are primarily due to the presence of hydroxycitric acid (HCA, as Super CitriMax) in the formulations.
Stohs SJ, Preuss HG, Ohia SE, Kaats GR, Keen CL, Williams LD, Burdock GA.   +6 more
europepmc   +4 more sources

Evaluation of in vitro toxicity of common phytochemicals included in weight loss supplements using ¹H NMR spectroscopy. [PDF]

FEBS Open Bio
We investigated the toxicity of 12 active compounds commonly found in herbal weight loss supplements (WLS) using human liver and colon cell models. Epigallocatechin‐3‐gallate was the only compound showing significant toxicity. Metabolic profiling revealed protein degradation, disrupted energy and lipid metabolism suggesting that the inclusion of EGCG ...
Davies EC, Maker GL, Musgrave IF, Lodge S.   +3 more
europepmc   +2 more sources

Absolute Configuration of Hydroxycitric Acid Produced by Microorganisms

Bioscience, Biotechnology and Biochemistry, 2006
Optical resolution for (2S,3R) and (2R,3S)-hydroxycitric acid (HCA) enantiomers was developed using chiral column chromatography. HCA from Bacillus megaterium G45C and Streptomyces sp. U121, newly isolated in our previous study, was analyzed to determine the absolute configuration. These results indicate that both strains generate optically pure (2S,3R)
HIDA, Hiroyuki, YAMADA, Takashi, YAMADA, Yasuhiro   +2 more
exaly   +3 more sources

A clinical and computational study on anti-obesity effects of hydroxycitric acid. [PDF]

RSC Adv, 2019
Hydroxycitric acid (HCA), a major active ingredient of Garcinia cambogia extracts, is known to suppress body weight gain and fat synthesis in animals and humans.
Tomar M, Rao RP, Dorairaj P, Koshta A, Suresh S, Rafiq M, Kumawat R, Paramesh R, V BU, Venkatesh KV.   +9 more
europepmc   +4 more sources

Applicability of <i>Hibiscus sabdariffa</i> L. Extract With Anti-Inflammatory Potential in Human Health: A Review. [PDF]

Food Sci Nutr
O artigo de revisão explora os potenciais benefícios anti‐inflamatórios do extrato de Hibiscus sabdariffa L. para a saúde humana. O objetivo é fornecer uma análise detalhada das propriedades terapêuticas da planta e sua aplicabilidade no tratamento de condições relacionadas à inflamação. ABSTRACT Studies demonstrate the health benefits of H. sabdariffa
Nogueira da Cruz ACS, Madruga Mesquita MJTA, Dantas GKR, Silva ER, Falcone De Oliveira VC, Rezende HM, Frota GM, Cavalcante M, Garcês JRC, Souza de Andrade M, Cartagenes MDSS.   +10 more
europepmc   +2 more sources

In vitro and in vivo toxicity of garcinia or hydroxycitric Acid: a review. [PDF]

Evid Based Complement Alternat Med, 2012
Obesity is one of the pandemic chronic diseases commonly associated with health disorders such as heart attack, high blood pressure, diabetes or even cancer. Among the current natural products for obesity and weight control,Garciniaor more specifically hydroxycitric acid (HCA) extracted fromGarciniahas been widely used.
Chuah LO, Yeap SK, Ho WY, Beh BK, Alitheen NB.   +4 more
europepmc   +5 more sources

Synergistic Anti-Obesity Effect of <i>Akkermansia muciniphila</i> AKM Lab-01 and <i>Garcinia cambogia</i> Extract via Gut Microbiota Remodeling in Diet-Induced Obese Mice. [PDF]

Food Sci Nutr
Combined administration of pasteurized Akkermansia muciniphila (AKM Lab‐01) and Garcinia cambogia extract (GCE) alleviates high‐fat‐diet‐induced obesity in mice by reducing adiposity, metabolic disturbances, and adipose inflammation, while remodeling gut microbiota and adipose transcriptome, revealing a gut‐host metabolic axis that underpins the ...
Huang B, Chen Z, Xue W, Pu Z, Zhou Y, Koay SSN, Kong P, Zhao Y, Tai L, Lan Z, Xian Y, Chen AJ.   +11 more
europepmc   +2 more sources

Sauerkraut-derived LAB strains as potential probiotic candidates for modulating carbohydrate digestion attributing bacterial organic acid profiling to antidiabetic activity. [PDF]

Food Sci Nutr
Molecular modeling studies of organic acid. Abstract Sauerkraut‐derived lactic acid bacterial (LAB) strains have gained attention due to their potential health benefits. This study focuses on evaluating seven Sauerkraut‐derived RAMULAB strains isolated from sauerkraut, aiming to identify promising candidates for modulating α‐glucosidase (AG) and α ...
Huligere SS, Kumari V B C, Patil SM, M K J, Wong LS, Kijsomporn J, Al-Tamimi JH, Ramu R.   +7 more
europepmc   +2 more sources

Hydroxycitric Acid Inhibits Chronic Myelogenous Leukemia Growth through Activation of AMPK and mTOR Pathway. [PDF]

Nutrients, 2022
Verrelli D, Dallera L, Stendardo M, Monzani S, Pasqualato S, Giorgio M, Pallavi R.   +6 more
europepmc   +2 more sources