Integrative Multi-Omics Identify Key Secondary Metabolites Linked to Acid Tolerance in <i>Leptospirillum ferriphilum</i>. [PDF]
Li Y +7 more
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Exploring Ectoine Production From Methanol, Formate, and Electrochemically Produced Formate by <i>Methyloligella halotolerans</i>. [PDF]
Kas A +5 more
europepmc +1 more source
Lon protease reprograms cellular physiology of <i>Streptomyces coelicolor</i> resulting in enhance antibiotic production. [PDF]
Bayraktar A +4 more
europepmc +1 more source
New isolates refine the ecophysiology of the Roseobacter CHAB-I-5 lineage. [PDF]
Lanclos VC +12 more
europepmc +1 more source
Biocatalytic C-H oxidation meets radical cross-coupling: Simplifying complex piperidine synthesis. [PDF]
He J +6 more
europepmc +1 more source
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Interaction of ectoine and hydroxyectoine with protein: fluorescence study
Chemical Papers, 2021Ectoine and hydroxyectoine are well known extremolytes that accumulate in halophilic and halotolerant microorganisms. They are investigated as protein stabilizers and as excipients in protein formulations and biopharmaceuticals. However, their effect is quite controversial.
Jolanta Sereikaite, Ruta Gruskiene
exaly +2 more sources
Interaction of bovine lactoperoxidase with hydroxyectoine: stabilizing effect study
Biologia (Poland), 2021Due to the wide range of Lactoperoxidase (LPO) application in the food production and medicine, stabilization of this enzyme seems to be necessary. In this study, different methods, such as fluorescence spectroscopy, FTIR spectra, docking studies, and enzyme activity assay were used to investigate the effects of hydroxyectoine on the stability and ...
Hashem Nayeri
exaly +2 more sources
Ectoine and hydroxyectoine inhibit aggregation and neurotoxicity of Alzheimer's β‐amyloid [PDF]
β‐Amyloid peptide (Aβ) is the major constituent of senile plaques, the key pathological feature of Alzheimer's disease. Aβ is physiologically produced as a soluble form, but aggregation of Aβ monomers into oligomers/fibrils causes neurotoxic change of the peptide.
Georg Lentzen, Chan Beum Park
exaly +4 more sources
Extrinsic protein stabilization by the naturally occurring osmolytes β-hydroxyectoine and betaine
Thermodynamic aspects of protein stabilization by two widespread naturally occurring osmolytes, beta-hydroxyectoine and betaine, were studied using differential scanning calorimetry (DSC) and bovine ribonuclease A (RNase A) as a model protein. The osmolyte beta-hydroxyectoine purified from Marinococcus was found to be a very efficient stabilizer.
Stefan Knapp
exaly +3 more sources
High-yield cultivation of Marinococcus M52 for production and recovery of hydroxyectoine
Research in Microbiology, 2006Ectoine and hydroxyectoine, produced by Halomonas ssp. and Marinococcus ssp., have been extensively characterized and proposed for biotechnological applications. Large-scale production of ectoine was achieved by implementing the so-called "milking process" by Bitop (Witten, Germany) and commercializing compatible solutes as stabilizers for biological ...
Chiara Schiraldi, Mario De Rosa
exaly +4 more sources

