Results 51 to 60 of about 5,125,991 (297)

Oxidative stress parameters in plasma of Huntington's disease patients, asymptomatic Huntington's disease gene carriers and healthy subjects : a cross-sectional study [PDF]

, 2007
BACKGROUND : Animal data and postmortem studies suggest a role of oxidative stress in the Huntington's disease (HD), but in vivo human studies have been scarce.
Babić, Tomislav, Hećimović, Silva, Klepac, Nataša, Klepac, Ratimir, Relja, Maja, Trkulja, Vladimir   +5 more
core   +1 more source

Adult vitamin D deficiency leads to behavioural and brain neurochemical alterations in C57BL/6J and BALB/c mice [PDF]

, 2013
Epidemiological evidence suggests that low levels of vitamin D may predispose people to develop depression and cognitive impairment. While rodent studies have demonstrated that prenatal vitamin D deficiency is associated with altered brain development ...
Burne, Thomas H. J., Eyles, Darryl W., Groves, Natalie J., Kesby, James P., Mackay-Sim, Alan, McGrath, John J.   +5 more
core   +1 more source

Seasonal variation of serotonin turnover in human cerebrospinal fluid, depressive symptoms and the role of the 5-HTTLPR. [PDF]

, 2013
Studying monoaminergic seasonality is likely to improve our understanding of neurobiological mechanisms underlying season-associated physiological and pathophysiological behavior.
Bakker, SC, Boks, MPM, Borgdorff, P, Bruins, P, Buizer-Voskamp, JE, Cantor, RM, DeYoung, J, Eijkemans, MJC, Horvath, S, Kahn, RS, Lentjes, E, Lu, A, Luykx, JJ, Ophoff, RA, Strengman, E, van Dongen, EPA, van Geloven, N   +16 more
core   +7 more sources

Macrogenomic and Metabolomic Analyses Reveal Mechanisms of Gut Microbiota and Microbial Metabolites in Diarrhea of Weaned Piglets

Animals
Recent studies have shown a correlation between piglet diarrhea and the gut microbiota. However, the precise mechanism by which intestinal microorganisms and their metabolites influence diarrhea in weaned piglets remains unclear.
Fei Xie, Mei Zhou, Xiaojin Li, Shenghe Li, Man Ren, Chonglong Wang   +5 more
doaj   +1 more source

Predator stress-induced depression is associated with inhibition of hippocampal neurogenesis in adult male mice

Neural Regeneration Research, 2019
Stress has been suggested to disturb the 5-hydroxytryptamine system and decrease neurogenesis, which contribute to the development of depression. Few studies have investigated the effect of predator stress, a type of psychological stress, on depression ...
Yan-Ping Wu, Hua-Ying Gao, Shu-Hua Ouyang, Hiroshi Kurihara, Rong-Rong He, Yi-Fang Li   +5 more
doaj   +1 more source

Depressive disorder and gastrointestinal dysfunction after myocardial infarct are associated with abnormal tryptophan-5-hydroxytryptamine metabolism in rats. [PDF]

PLoS ONE, 2017
In this study, we investigated the relationship between tryptophan-5-hydroxytryptamine metabolism, depressive disorder, and gastrointestinal dysfunction in rats after myocardial infarction.
Xiaofang Lu, Yuefen Wang, Chunyan Liu, Yangang Wang   +3 more
doaj   +1 more source

The unilateral nigral lesion induces dramatic bilateral modification on rat brain monoamine neurochemistry [PDF]

, 2009
6-Hydroxydopamine (6-OHDA) is a neurotoxic compound commonly used to induce dopamine (DA) depletion in the nigrostriatal system, mimicking Parkinson's disease (PD) in animals.
Beal, Betarbet, Bezard, Blum, Breese, Carta, Dauer, Deumens, Di Giovanni, Di Giovanni, Di Giovanni, Di Giovanni, Di Giovanni, Di Matteo, Di Matteo, Di Matteo, Eidelberg, Enz, Esposito, Fornaguera, Glinka, Hahn, Hornykiewicz, Hornykiewicz, Hornykiewicz, Jellinger, Liang, Luthman, Luthman, Miller, Molina-Holgado, Paxinos, Porter, Sachs, Scherman, Schober, Schwarting, Sherman, Taylor, Ungerstedt, Von Bohlen und Halbach, Zhou   +41 more
core   +1 more source

Valproic Acid-Induced Autistic-Like Behavior Is Accompanied by Intestinal Damage Driving Changes in Gut Permeability in a Sex-Dependent Way in Rats. [PDF]

J Neurochem
Exposure to valproic acid (VPA) caused sex‐dependent changes in the gut–brain axis, with more pronounced effects in males, including intestinal barrier dysfunction, blood–brain barrier (BBB) impairment, and social behavior deficits. Females showed intestinal inflammation and increased vascular permeability in the ileum, but no behavioral or intestinal ...
Longo B, Nunes RKS, Cazarin CA, Silva TFQE, Sievers J, Nilz ACDS, Venzon L, da Silva LM, Willrich CH, Cury BJ, Costa RA, de Souza MM, Stern CAJ, Zampronio AR, da Silva LM.   +14 more
europepmc   +2 more sources

Increased CSF levels of aromatic amino acids in hip fracture patients with delirium suggests higher monoaminergic activity [PDF]

, 2016
textabstractBackground: To examine whether delirium in hip fracture patients was associated with changes in the levels of amino acids and/or monoamine metabolites in cerebrospinal fluid (CSF) and serum.
Leiv Otto Watne, Ane-Victoria Idland, Durk Fekkes, Johan Raeder, Frede Frihagen, Anette Hylen Ranhoff, Farrukh Abbas Chaudhry, Knut Engedal, Torgeir Bruun Wyller, Bjørnar Hassel, SK Inouye, AJ Bruce, V Juliebo, TT Hshieh, JR Maldonado, JD Fernstrom, JM Flacker, RC Mast van der, PP Pandharipande, RC Mast van der, LO Watne, SK Inouye, AF Jorm, AF Jorm, MF Folstein, KI Shulman, KA Welsh, CP Hughes, TB Wyller, D Wade, ME Charlson, WA Knaus, D Dahlberg, TJ Cammen van der, D Fekkes, JD Fernstrom, AL Miller, G Papadopoulos, TN Robinson, RJ Osse, A Egberts, J Ramirez-Bermudez, HJ Koponen, A Wallin, M Sjogren, GJ Broussard   +45 more
core   +6 more sources

The Carbon Number‐specific Impact of Mineral Oil Saturated Hydrocarbons on Inducing Colonic Inflammation in Female and Male Fischer 344 Rats

Food Frontiers, EarlyView.
MOSH‐induced colonic alterations and sex‐specific metabolic pathways in female and male F344 rats. ABSTRACT This study investigated the effects of mineral oil saturated hydrocarbon (MOSH) sub‐fractions (C20‐30 and C30‐50) on the colon of male and female F344 rats and the underlying mechanisms.
Lin Zhu, Mingming Zhang, Hong Zhang, Hai Zhang, Boyan Gao, Liangli (Lucy) Yu, Yaqiong Zhang   +6 more
wiley   +1 more source