Results 61 to 70 of about 2,522,863 (212)
Glioma induced alterations in fecal short-chain fatty acids and neurotransmitters
CNS Oncology, 2020 Aim: To explore fecal short-chain fatty acids and neurotransmitter alterations in a mouse–glioma model and glioma patients. Methods: Liquid chromatography–mass spectrometry and 16S rRNA-sequencing from fecal samples were performed to measure metabolite ...
Antonio Dono +8 more
doaj +1 more source
British Journal of Pharmacology, EarlyView.Abstract Background and Purpose Nicotine dependence remains one of the leading causes of morbidity and mortality worldwide, with high relapse rates and post‐cessation weight gain representing persistent barriers to sustained abstinence. The incretin hormones glucose‐dependent insulinotropic polypeptide (GIP) and glucagon‐like peptide‐1 (GLP‐1) have ...
Christian E. Edvardsson +5 more
wiley +1 more source
Cannabinoid exposure during pregnancy: Cardiorespiratory effects and offspring outcomes
The Journal of Physiology, EarlyView.Abstract figure legend Prenatal exposure to cannabinoids has been investigated across human and animal studies to understand its impact on physiological development. Evidence suggests that early‐life cannabinoid exposure influence multiple developmental processes, extending beyond neurodevelopmental outcomes to potentially affect placental function ...
Luis Gustavo A. Patrone +1 more
wiley +1 more source
Frontiers in Behavioral Neuroscience, 2019 During the past decade, there has been a substantial rise in the knowledge about the effects of gut microbiota on host physiology and behavior, including depressive behavior.
Iva Lukić +3 more
doaj +1 more source
The Metabolomics of Childhood Atopic Diseases: A Comprehensive Pathway-Specific Review
Metabolites, 2020 Asthma, allergic rhinitis, food allergy, and atopic dermatitis are common childhood diseases with several different underlying mechanisms, i.e., endotypes of disease.
Mette S. Schjødt +2 more
doaj +1 more source
Clinical Pharmacology &Therapeutics, Volume 120, Issue 4, Page 1016-1026, October 2026.Regulatory agencies request the assessment of the potential of new drugs to cause transporter‐mediated drug‐drug interactions (DDI). This assessment can be improved by integrating endogenous biomarkers during drug development. Regarding the renal excretion of drugs such as metformin, the organic cation transporter (OCT) 2 and multidrug and toxin ...
Jana Picurová +5 more
wiley +1 more source
Bile Acid Induced Diarrhoea Pathophysiological and Clinical Aspects [PDF]
, 2008 A common cause for referral to gastroenterologists is chronic watery diarrhoea. Approximately 40% of these patients have idiopathic bile acid malabsorption (BAM) – a condition with unknown aetiology.
Bajor, Antal
core +1 more source
Pathogens, 2018 Catecholamine and serotonin are biogenic amines (BAs) that serve as neurotransmitters and play an important role in the regulation of cardinal functions that are mainly altered during central nervous system (CNS) infections.
Aneela Taj, Nusrat Jamil
doaj +1 more source
Advanced Science, Volume 13, Issue 52, 18 September 2026.A pH/MMP dual‐responsive Bifidobacterium longum (BL) hydrogel (INPs@BL@Gel) functionalized with baicalin, tyrosine, and inulin is constructed. It enables gastric protection, inflammation‐targeted release, and prolonged intestinal colonization. By remodeling gut microbiota, elevating beneficial neuroactive metabolites (homovanillic acid, short‐chain ...
Shuo Zhang +17 more
wiley +1 more source
Regulatory Pathways of Monoamine Oxidase A during Social Stress
Frontiers in Neuroscience, 2017 Social stress has a high impact on many biological systems in the brain, including serotonergic (5-HT) system—a major drug target in the current treatment for depression. Hyperactivity of hypothalamic-pituitary-adrenal (HPA) axis and monoamine oxidase A (
Yuki Higuchi +2 more
doaj +1 more source