Results 151 to 160 of about 8,352 (265)

Bioresponsive pseudoGlucosinolates (psGSLs) Release Isothiocyanates (ITCs) in the Presence of Nitroreductases

Chemistry – A European Journal, Volume 32, Issue 25, 2 July 2026.
This work introduces the concept of pseudoglucosinolates (psGSLs) and reports the synthesis and evaluation of nitroreductase‐responsive psGSLs. These compounds represent a complementary prodrug strategy to natural glucosinolates (GSLs) for the controlled release of isothiocyanates (ITCs), enabling bio‐responsive protein labeling, as demonstrated in ...
Claire C. Jimidar, Charity S. G. Ganskow, Mervic D. Kagho, Aishi Chakrabarti, Lorenz Wiese, Michael Zollo, Ulrike Beutling, Leona C. Cesar, Julia Morud, Kamila Bugaj, Mark Brönstrup, Stephan A. Sieber, Stephan M. Hacker, Philipp Klahn   +13 more
wiley   +1 more source

Synthesis of <i>N</i>-Substituted Hydroxamic Acids through a Pentafluoropyridine-Mediated Procedure. [PDF]

J Org Chem
Bonn DE, Blundell TJ, Jenner M, Brittain WDG.   +3 more
europepmc   +1 more source

A Review of Breath Sensing for Disease Monitoring and Diagnosis: Breathomics, Artificial Intelligence, and Nanomaterials for the Future of Medicine

Advanced Sensor Research, Volume 5, Issue 7, July 2026.
Breathomics is established as a non‐invasive diagnostic strategy by combining volatile organic compound biomarkers, nanomaterial‐based sensor arrays, and AI‐driven classification. Key diseases, sensing materials, and analytical challenges are critically compared, revealing how portable, data‐enabled breath platforms are moving toward clinically useful ...
Anesu Nyabadza, Mayur Makhesana, Suman Chatterjee, Dermot Brabazon   +3 more
wiley   +1 more source

Palmitic Acid Promotes Antiviral Innate Immunity via ZDHHC20‐Mediated CMPK2 Palmitoylation

Advanced Science, Volume 13, Issue 37, 3 July 2026.
Metabolites have important functions in innate immune activation and regulation. Wang et al. uncover metabolic regulation of antiviral immunity through CMPK2 palmitoylation, which regulates CMPK2 mitochondrial localization and is promoted by ZDHHC20 but reversed by PPT1, inhibition of which antagonizes viral infection in mice.
Yujia Wang, Zenghui Cui, Yunkai Zhang, Zhiqing Li, Xuetao Cao   +4 more
wiley   +1 more source

Reactions of vicinal aliphatic bis(hydroxylamines) with trifunctionalized methane derivatives

ARKIVOC, 2011
Evgeny A. Mostovich, Dmitrii G. Mazhukin, Tatyana V. Rybalova   +2 more
doaj   +1 more source

Engineering Enantiocomplementary Protoglobins for Stereoconvergent Construction of <i>N</i>-Alkylated α-Aminoketones. [PDF]

J Am Chem Soc
Qin ZY, Li ZQ, Zhang C, Heise JL, Mao R, Wu SJ, Houk KN, Goddard Iii WA, Arnold FH.   +8 more
europepmc   +1 more source

Regulation of Endoplasmic Reticulum Stress Suppresses Early Pro‐Tumorigenic Events During N‐Nitrosodiethylamine‐Induced Hepatocarcinogenesis

Journal of Biochemical and Molecular Toxicology, Volume 40, Issue 7, July 2026.
Schematic illustration of the effect of BIX in attenuating the initiation stage of hepatocarcinogenesis. BIX pre‐treatment mitigated N‐nitrosodiethylamine‐induced ER stress, DNA damage, and downstream pro‐tumorigenic events during the initiation phase. It preserved DNA repair capacity, reduced inflammation and cellular proliferation, thereby inhibiting
Maya P. Shetty, Smita Hegde, Sanjay Bharati   +2 more
wiley   +1 more source

Nitrones: Comprehensive Review on Synthesis and Applications. [PDF]

Molecules
Santos RALS, Silva AMS, Pinto DCGA.
europepmc   +1 more source

Chemical Speciation Defines Archaeal Ammonia‐Oxidizer Distribution in Yellowstone Hot Springs

Journal of Geophysical Research: Biogeosciences, Volume 131, Issue 7, July 2026.
Abstract The hot springs of Yellowstone National Park (YNP) provide a natural laboratory for investigating the influence of chemical speciation and energy availability on the distribution of microbes. Among 133 inorganic chemotrophic energy supplies, total dissolved ammonia oxidation was consistently one of the highest across 63 YNP hot spring samples.
Katelyn Weeks, Elizabeth Trembath‐Reichert, Jordyn Robare, R. Vince Debes II, Alta E. G. Howells, Everett Shock   +5 more
wiley   +1 more source

Cyclic Hydroxylamines for Native Residue-Forming Peptide Ligations: Synthesis of Ubiquitin and Tirzepatide. [PDF]

J Am Chem Soc
Han J, Hirao K, Mikami T, Nötel NY, Seidl LL, Bode JW.   +5 more
europepmc   +1 more source