Results 141 to 150 of about 10,973 (280)
Enantioselective Copper-Catalyzed Synthesis of Hydroxylamines via Hydrofunctionalization of Alkenes using Nitroalkanes. [PDF]
Law JA +7 more
europepmc +1 more source
We evaluated Lasiocampa quercus as an overwintering host for the koinobiont larval endoparasitoid Glyptapanteles porthetriae by exposing parasitized larvae to different environmental conditions and comparing parasitoid development with that in the primary host Lymantria dispar.
Thomas Zankl, Christa Schafellner
wiley +1 more source
Modulating IDO1 and TDO Inhibition Through Structural Modification of Diaryl Hydroxylamines. [PDF]
Foscolos AS +8 more
europepmc +1 more source
Automodification of N‐terminal serine residues facilitates PARP2 release from DNA
PARP2 is involved in detecting DNA damage and its N‐terminal role is largely unknown. Based on biochemical and biophysical data, our findings suggest that in the presence of HPF1, N‐terminal serine 8 and 73 are enriched in auto‐ADP‐ribosylation. Our results provide insight into the mechanistic role of PARP2 N‐terminus in the PARylation‐dependent ...
Saurabh Singh Dhakar +6 more
wiley +1 more source
Nicotinamide phosphoribosyltransferase inhibitors, design, preparation and SAR. [PDF]
Annemette Thougaard +66 more
core +1 more source
TGF‐β signaling regulates extracellular vesicle (EV) release in cancer cells by modulating the expression and activity of genes associated with EV biogenesis. The TGF‐β‐induced upregulation of RAB4A expression facilitates fast endosomal recycling, a process that limits the fusion of multivesicular bodies with the plasma membrane and EV secretion. Hence,
Dorival Mendes Rodrigues‐Junior +5 more
wiley +1 more source
Nitrones: Comprehensive Review on Synthesis and Applications. [PDF]
Santos RALS, Silva AMS, Pinto DCGA.
europepmc +1 more source
An Australian standard of care for Niemann–Pick disease type C
Abstract Background Niemann–Pick disease type C (NP‐C) is the fifth most prevalent lysosomal disorder in Australia. Diagnostic delay is common, impacted by disease heterogeneity, limited awareness within clinical gateway services and exclusion from state‐based newborn screening programmes.
Michel Tchan +23 more
wiley +1 more source

