Polar-to-Radical Crossover in Catalyst-Free Olefin Halo-Hydroxylamination: A Direct Route to Multifunctional Electrophilic Hydroxylamines [PDF]
JACS AuYoung-Do Kwon +7 more
doaj +2 more sources
Cyclic Hydroxylamines as Monitors of Peroxynitrite and Superoxide-Revisited
Antioxidants, 2021 There is a considerable need for methods that allow quantitative determination in vitro and in vivo of transient oxidative species such as peroxynitrite (ONOOH/ONOO−) and superoxide (HO2•/O2•−).
Uri Samuni, Amram Samuni, Sara Goldstein
doaj +1 more source
Urea Synthesis from Isocyanides and O-Benzoyl Hydroxylamines Catalyzed by a Copper Salt
Molecules, 2022 In the presence of CuOAc, a series of unsymmetric ureas can be generated in moderate to good yields under mild reaction conditions (10 mol% of CuOAc, 2 equiv t-BuONa or PhONa, 30 °C), using aryl isocyanides and O-benzoyl hydroxylamines as the readily ...
Ning Yu +5 more
doaj +1 more source
Molecules, 2022 Herein the reaction mechanism and the origin of stereoselectivity of asymmetric hydrogenation of oximes to hydroxylamines catalyzed by the cyclometalated iridium (III) complexes with chiral substituted single cyclopentadienyl ligands (Ir catalysts A1 and
Qaim Ali +6 more
doaj +1 more source
Kinetic resolution of indolines by asymmetric hydroxylamine formation
Nature Communications, 2021 Catalytic kinetic resolution of amines is a longstanding challenge in chemical synthesis. Here, the authors report on titanium‐catalysed asymmetric oxygenation with hydrogen peroxide for kinetic resolution of secondary amines through oxygenation to ...
Gang Wang +3 more
doaj +1 more source
2-aminophenols containing electron-withdrawing groups from N-aryl hydroxylamines [PDF]
, 2010 Reaction of substituted N-aryl hydroxylamines with methanesulfonyl chloride, p-toluenesulfonyl chloride, or trifluoromethanesulfonic anhydride under basic conditions leads to the rearranged 2-aminophenols (45-94%).
Cooper, Anthony W. J. +3 more
core +1 more source
A triplet biradical with double bidentate sites based on tert-butyl pyridyl nitroxide as a candidate for strong ferromagnetic couplers [PDF]
, 2018 We synthesised a new biradical, 34bpybNO, having two chelating radical sites and demonstrated its crystal structure and ground triplet nature. Frozen-solution magnetic measurement and electron spin resonance results revealed a strong intramolecular ...
Atsushi Okazawa +3 more
core +2 more sources
O-((Ferrocenyl)(3-fluorophenyl)methyl)hydroxylamine
Molbank, 2022 Based on the diaryl hydroxylamine scaffold, which exhibits the potential to inhibit all three enzymes of the first step of the kynurenine pathway, the main tryptophan degradation pathway in mammals, which is often activated in cancer, we report herein ...
Angeliki S. Foscolos +3 more
doaj +1 more source
Detection of reactive oxygen and nitrogen species by electron paramagnetic resonance (EPR) technique [PDF]
, 2017 During the last decade there has been growing interest in physical-chemical oxidation processes and the behavior of free radicals in living systems. Radicals are known as intermediate species in a variety of biochemical reactions.
Gurer-Orhan, H., Saso, L., Suzen, S.
core +2 more sources
Highly efficient methods for the one-pot synthesis of b-substituted enones [PDF]
, 2006 A mild and practically-convenient one-pot procedure for the direct b-substitution of enones has been developed using a conjugate addition–oxidation strategy with a full range of copper-based reagents and N-tert-butylphenylsulfinimidoyl chloride; alkyl ...
Bartoli +29 more
core +1 more source