Results 11 to 20 of about 7,080 (240)

Urea Synthesis from Isocyanides and O-Benzoyl Hydroxylamines Catalyzed by a Copper Salt

Molecules, 2022
In the presence of CuOAc, a series of unsymmetric ureas can be generated in moderate to good yields under mild reaction conditions (10 mol% of CuOAc, 2 equiv t-BuONa or PhONa, 30 °C), using aryl isocyanides and O-benzoyl hydroxylamines as the readily ...
Ning Yu, Jing-Fang Lv, Shi-Mei He, Yanyan Cui, Ye Wei, Kun Jiang   +5 more
doaj   +1 more source

The Origin of Stereoselectivity in the Hydrogenation of Oximes Catalyzed by Iridium Complexes: A DFT Mechanistic Study

Molecules, 2022
Herein the reaction mechanism and the origin of stereoselectivity of asymmetric hydrogenation of oximes to hydroxylamines catalyzed by the cyclometalated iridium (III) complexes with chiral substituted single cyclopentadienyl ligands (Ir catalysts A1 and
Qaim Ali, Yongyong Chen, Ruixue Zhang, Zhewei Li, Yanhui Tang, Min Pu, Ming Lei   +6 more
doaj   +1 more source

Kinetic resolution of indolines by asymmetric hydroxylamine formation

Nature Communications, 2021
Catalytic kinetic resolution of amines is a longstanding challenge in chemical synthesis. Here, the authors report on titanium‐catalysed asymmetric oxygenation with hydrogen peroxide for kinetic resolution of secondary amines through oxygenation to ...
Gang Wang, Ran Lu, Chuangchuang He, Lei Liu   +3 more
doaj   +1 more source

O-((Ferrocenyl)(3-fluorophenyl)methyl)hydroxylamine

Molbank, 2022
Based on the diaryl hydroxylamine scaffold, which exhibits the potential to inhibit all three enzymes of the first step of the kynurenine pathway, the main tryptophan degradation pathway in mammals, which is often activated in cancer, we report herein ...
Angeliki S. Foscolos, Maria Georgiou, Minas S. Papadopoulos, Aristeidis Chiotellis   +3 more
doaj   +1 more source

Synthesis of Alkyl Aryl Sulfones via Reaction of N-Arylsulfonyl Hydroxyamines with Electron-Deficient Alkenes

Molecules, 2016
Alkyl aryl sulfones were prepared in high yields via the reaction of N-arylsulfonyl hydroxylamines with electron-deficient alkenes. These reactions have the advantages of simplicity, easily available starting materials and mild reaction conditions.
Yunhui Bin, Ruimao Hua
doaj   +1 more source

Expedient Organocatalytic Syntheses of 4-Substituted Pyrazolidines and Isoxazolidines

Molecules, 2016
The efficient organocatalytic synthesis of heterocyclic systems of biological relevance is a subject of growing interest. We have found that the pyrrolidine/benzoic acid-catalyzed reaction of α-substituted propenals such as methacrolein, 2-benzylpropenal
Tarek Yousfi, Alysha Elliott, Messiad Hanane, Rachid Merdes, Albert Moyano   +4 more
doaj   +1 more source

Polyalkoxy Nitrones as Chiral Building Blocks in Asymmetric Synthesis

Molecules, 1999
Optically active nitrones derived from both aldoses and dialdoses add metallated heterocycles in a stereocontrolled way depending on the nature of the Lewis acid used as a precomplexing agent of the nitrone.
Tomás Tejero, Pedro Merino
doaj   +1 more source

Electrochemical Evaluation of Nitroxyl Radical Catalysts and Electrochemical Detection of Cyclosporin A

International Journal of Electrochemical Science, 2021
Nitroxyl radical catalysts oxidize alcohols under an applied electric potential. It is possible to quantify the alcohol concentration from the resulting oxidation current.
Sachiko Komatsu, Yusuke Sasano, Kyoko Sugiyama, Kazuhiro Watanabe, Masayuki Kumano, Kentaro Yoshida, Tetsuya Ono, Yoshiharu Iwabuchi, Tsutomu Fujimura, Katsuhiko Sato, Yoshitomo Kashiwagi   +10 more
doaj   +1 more source

Precursor‐Directed Synthesis of Apoptosis‐Initiating N‐Hydroxyalkyl Phenylbenzoisoquinolindione Alkaloids

ChemistryOpen, 2022
A precursor‐directed approach to access N‐hydroxyalkyl phenylbenzoisoquinolindiones (PBIQs) has been developed. Incubation of plant material of Xiphidium caeruleum with hydroxylamines of various chain lengths (C2, C4, C6, C8, C10 and C12) resulted in 11 ...
Prof. Dr. Yu Chen, Dr. Hans‐Martin Dahse, Dr. Christian Paetz, Dr. Bernd Schneider   +3 more
doaj   +1 more source

Oxidation of N,N-Disubstituted Hydroxylamines to Nitrones: The Search for More Sustainable Selective and Practical Stoichiometric Oxidants

CHIMIA, 2017
Nitrones are key intermediates for the total synthesis of nitrogen-containing natural products and analogues. The direct oxidation of the corresponding N,N-disubstituted hydroxylamines is one of the most straightforward methods to access such ...
Camilla Matassini, Francesca Cardona
doaj   +1 more source