Results 91 to 100 of about 111,305 (353)

Manipulating Unisexual–Sexual Reproduction Transition to Engineer Genome‐Reconstructed Polyploids

open access: yesAdvanced Science, EarlyView.
This study developed an efficient approach to generate genome‐reconstructed polyploids involving unisexual gynogenetic Carassius gibelio, sexual C. auratus, and sexual C. cuvieri. The selected superior clone inherited gynogenesis ability of C. gibelio and herpesvirus resistance of wild C.
Meng Lu   +9 more
wiley   +1 more source

Peptide Hormone‐Mediated Regulation of Plant Development and Environmental Adaptability

open access: yesAdvanced Science, EarlyView.
In this review, recent advances in understanding the roles of plant peptide hormones in regulating growth, reproduction, and environmental adaptability are systematically summarized. It further elucidates the challenges in studying these peptides, such as their low abundance, functional redundancy, and complex signaling mechanisms, and highlights their
Xin Li   +8 more
wiley   +1 more source

Shaping of a Reactive Manganese Catalyst Enables Access to Polyfunctionalized Cyclohexanes via Enantioselective C(sp3)─H Bond Oxidation of 1,3‐meso Diethers

open access: yesAngewandte Chemie, EarlyView.
Structural shaping of a highly reactive chiral Mn‐oxo species translates into exceptionally enantioselective C─H oxidation catalyst of cyclohexyl 1,3‐meso diethers (up to >99% ee) leading to polyfunctionalized cyclohexanes. Abstract Chiral polyoxygenated cyclohexanes are valuable constituents of biologically relevant products.
Andrea Palone   +7 more
wiley   +2 more sources

Highly Active IrRuOx/MnOx Electrocatalysts with Ultralow Anode PGM Demand in Proton Exchange Membrane Electrolyzers

open access: yesAdvanced Energy Materials, EarlyView.
MnOx‐supported IrRuOx exhibits outstanding OER performance in both liquid electrolytes and real cell environments. The MnOx not only enhances the dispersion of IrRuOx but also induces a compressive strain effect. The incorporation of Ru leads to surface reconstruction.
Jiaqi Kang   +8 more
wiley   +1 more source

Conditional Stabilization of the Hypoxia‐Inducible Factor HIF1α— Photoswitchable Stapled Peptides Prevent Elongin BC–Mediated Degradation

open access: yesAngewandte Chemie, EarlyView.
Visible‐light photoswitchable peptides enable the stabilization of the hydroxylated hypoxia transcription factor 1α (HIF1α—OH) by targeting the pVHL‐EloBC interaction. Significant differences in conformation, binding, and transcription of HIF‐targeted genes between the photostationary states (PSS) were demonstrated.
Van Tuan Trinh   +7 more
wiley   +2 more sources

Lactones 41. Synthesis and Microbial Hydroxylation of Unsaturated Terpenoid Lactones with p-Menthane Ring Systems

open access: yesMolecules, 2013
Racemic [(±)-4-isopropyl-1-methyl-7-oxa-cis-bicyclo[4.3.0]non-4-en-8-one] and optically active d,e-unsaturated lactones [(-)-(1R,6R)-4-isopropyl-1-methyl-7-oxabicyclo[4.3.0]non-4-en-8-one and (+)-(1S,6S)-4-isopropyl-1-methyl-7-oxabicyclo[4.3.0] non-4-en ...
Czesław Wawrzeńczyk   +1 more
doaj   +1 more source

RHOBTB3 promotes proteasomal degradation of HIFα through facilitating hydroxylation and suppresses the Warburg effect

open access: yesCell Research, 2015
Hypoxia-inducible factors (HIFs) are master regulators of adaptive responses to low oxygen, and their α-subunits are rapidly degraded through the ubiquitination-dependent proteasomal pathway after hydroxylation.
Chensong Zhang   +17 more
semanticscholar   +1 more source

Selective Electrocatalytic Oxidation of Phenol to Benzoquinone via Water Splitting Using a Nonprecious Metal‐Based Electrocatalyst

open access: yesAdvanced Energy and Sustainability Research, EarlyView.
A green process has been developed utilizing electrochemistry to convert inexpensive, readily available phenol derived from lignin into para‐benzoquinone, a valuable chemical widely used in the manufacturing and chemical industries. For the first time, a novel electrocatalytic oxidation system is achieved with high 96.2% conversion of phenols to para ...
Asad Ali   +4 more
wiley   +1 more source

The Iron–Sulfur Cluster of Bacterioferritin‐Associated Ferredoxin (Bfd): a “Biological Fuse” that Prevents Oxidative Damage to Cells?

open access: yesAngewandte Chemie, EarlyView.
When cellular iron is low, bacterioferritin (Bfr) releases its stored iron through a reductive process dependent on the [2Fe–2S] ferredoxin Bfd. Why accessing stored iron should depend on an iron‐requiring protein when iron is scarce is unclear. Here, we show that the Bfd [2Fe–2S] cluster is sensitive to oxidative stress, suggesting that it may act as ...
Justin M. Bradley   +4 more
wiley   +2 more sources

Probing Steroidal Substrate Specificity of Cytochrome P450 BM3 Variants

open access: yesMolecules, 2016
M01A82W, M11A82W and M01A82WS72I are three cytochrome P450 BM3 (CYP102A1) variants. They can catalyze the hydroxylation of testosterone (TES) and norethisterone at different positions, thereby making them promising biocatalysts for steroid hydroxylation.
Xing Liu   +3 more
doaj   +1 more source

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