Results 91 to 100 of about 97,747 (236)
Molecules, 2013 Racemic [(±)-4-isopropyl-1-methyl-7-oxa-cis-bicyclo[4.3.0]non-4-en-8-one] and optically active d,e-unsaturated lactones [(-)-(1R,6R)-4-isopropyl-1-methyl-7-oxabicyclo[4.3.0]non-4-en-8-one and (+)-(1S,6S)-4-isopropyl-1-methyl-7-oxabicyclo[4.3.0] non-4-en ...
Czesław Wawrzeńczyk +1 more
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Probing Steroidal Substrate Specificity of Cytochrome P450 BM3 Variants
Molecules, 2016 M01A82W, M11A82W and M01A82WS72I are three cytochrome P450 BM3 (CYP102A1) variants. They can catalyze the hydroxylation of testosterone (TES) and norethisterone at different positions, thereby making them promising biocatalysts for steroid hydroxylation.
Xing Liu +3 more
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Cell Research, 2015 Hypoxia-inducible factors (HIFs) are master regulators of adaptive responses to low oxygen, and their α-subunits are rapidly degraded through the ubiquitination-dependent proteasomal pathway after hydroxylation.
Chen-Song Zhang +17 more
semanticscholar +1 more source
Water adsorption and dissociation on BeO (001) and (100) surfaces [PDF]
arXiv, 2007 Plateaus in water adsorption isotherms on hydroxylated BeO surfaces suggest significant differences between the hydroxylated (100) and (001) surface structures and reactivities. Density functional theory structures and energies clarify these differences.
arxiv
Beilstein Journal of Organic Chemistry, 2015 Cytochrome P450 monooxygenases are useful biocatalysts for C–H activation, and there is a need to expand the range of these enzymes beyond what is naturally available.
Paul P. Kelly +5 more
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Elongation Factor 2 Kinase Is Regulated by Proline Hydroxylation and Protects Cells during Hypoxia
Molecular and Cellular Biology, 2015 Protein synthesis, especially translation elongation, requires large amounts of energy, which is often generated by oxidative metabolism. Elongation is controlled by phosphorylation of eukaryotic elongation factor 2 (eEF2), which inhibits its activity ...
C. E. Moore +6 more
semanticscholar +1 more source
Beilstein Journal of Organic Chemistry, 2017 Chiral phase-transfer catalysis is one of the major catalytic principles in asymmetric catalysis. A broad variety of different catalysts and their use for challenging applications have been reported over the last decades.
Johannes Schörgenhumer +2 more
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Molecules, 2010 Enantiomerically enriched hydroxy-substituted b-amino esters have been synthesized through CAL-B-catalyzed enantioselective hydrolysis in organic media.
Enikő Forró +5 more
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P4HA1 is a new regulator of the HIF-1 pathway in breast cancer
Cell Stress, 2019 Hypoxia-Inducible Factor (HIF)-1 is a transcription factor that plays the key role in response to low oxygen concentrations, or hypoxia. Activation of the HIF-1 pathway is not only crucial for normal tissue development and function, but also involved in ...
Ren Xu
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Journal of Lipid Research, 1990 7 alpha-Hydroxylation of cholesterol is a stereospecific reaction consisting of the replacement of the 7 alpha-hydrogen with a hydroxyl group. When cholesterol labeled with tritium at the 7 alpha position is administered, the hydroxylation of the ...
M Bertolotti +6 more
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