Mild Direct Remote Hydroxylation of Enals in Air. [PDF]
Liu F, Vicidomini A, Brenner-Moyer SE.
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Functional characterization of a novel <i>p</i>-coumarate 3-hydroxylase from <i>Trametes versicolor</i>. [PDF]
Hamajima L +8 more
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Functional characterization of steroid hydroxylation by cytochrome P450 enzymes from Rhodococcus erythropolis KB1. [PDF]
Ma J +7 more
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DIMORPH: an integrated multi-omics resource for camptothecin-producing plants. [PDF]
Lou Q +16 more
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Strategies for Optimizing the Yield and Function of Recombinant Collagen in Different Expression Systems: A Review. [PDF]
Cheng M +7 more
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Engineering a cytochrome P450 enzyme as a peroxygenase for selective hydroxylation of steroids. [PDF]
Tang T, Wang R, Chen Y.
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Simplified approaches to kinetic isotope effects in cytochrome P450-catalyzed reactions and relevance to deuterated drugs. [PDF]
Guengerich FP.
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The hydroxylation of tryptophan
Archives of Biochemistry and Biophysics, 1992Products of the chemical hydroxylation of tryptophan by Fenton and Udenfriend reactions are similar to those obtained by ionizing radiation. When tryptophan is exposed to either of these systems, a mixture of four hydroxytryptophans, oxindole-3-alanine, and N-formylkynurenine is formed.
Z, Maskos, J D, Rush, W H, Koppenol
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The mixture of products obtained when skatole is oxidized with the ferrous sulphate – ascorbic acid – EDTA – air system has been examined by means of paper and thin layer chromatographic techniques. 3-Methyloxindole, o-aminoacetophenone, N-formyl-o-aminoacetophenone, and the four isomeric hydroxyskatoles have been definitely identified. A number of, as
R A, HEACOCK, M E, MAHON
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Hydroxylation of desmethylimipramine: Dependence on the debrisoquin hydroxylation phenotype
Clinical Pharmacology and Therapeutics, 1987The 2-hydroxylation of desmethylimipramine (DMI) was studied in 14 healthy subjects previously phenotyped with respect to debrisoquin hydroxylation. After a single oral dose (25 mg), slow hydroxylators of debrisoquin had significantly lower total and metabolic clearances and longer plasma half-lives of DMI and excreted less 2-hydroxydesmethylimipramine
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