Results 311 to 320 of about 111,305 (353)
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Microbial hydroxylation of acetylaminosteroids
Steroids, 1998An investigation of the microbial biotransformation of a range of 3 beta-, 17 beta-, and 20-acetylamino C18 to C21 steroids by microorganisms known to hydroxylate conventional steroids has been undertaken, using Aspergillus ochraceus, Bacillus megaterium, Curvularia lunata, and Rhizoputus arrhizus. A. ochraceus and B.
Herbert L. Holland +2 more
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Analytical Biochemistry, 2001
Hydroxylation of l-phenylalanine (Phe) by hydroxyl radical (*OH) yields 4-, 3-, and 2-hydroxyl-Phe (para-, meta-, and ortho-tyrosine, respectively). Phe derivative measurements have been employed to detect *OH formation in cells and tissues, however, the specificity of this assay is limited since Phe derivatives also arise from intracellular Phe ...
Jay L. Zweier +6 more
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Hydroxylation of l-phenylalanine (Phe) by hydroxyl radical (*OH) yields 4-, 3-, and 2-hydroxyl-Phe (para-, meta-, and ortho-tyrosine, respectively). Phe derivative measurements have been employed to detect *OH formation in cells and tissues, however, the specificity of this assay is limited since Phe derivatives also arise from intracellular Phe ...
Jay L. Zweier +6 more
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Ligand-Promoted Pd-Catalyzed Oxime Ether Directed C–H Hydroxylation of Arenes
, 2015An efficient Pd-catalyzed oxime ether directed ortho C–H hydroxylation of arenes under neutral conditions has been developed. The efficiency of this hydroxylation is significantly improved by a ligand.
Yu-Feng Liang +5 more
semanticscholar +1 more source
Synthetic Communications, 1983
Abstract In connection with the introduction of hydroxy functions to the C-7 and C-9 positions of anthracycline antitumor antibiotics, 3 such as 4-demethoxydaunomycin (1)3 and of the hetero-anthracyclines such as 4-demethoxy xanthodaunomycin (2), 4-demethoxy thioxantho-daunomycin (3) and 4-demethoxy sulfoxodaunomycin (4), we have discovered that for ...
K. Marat +4 more
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Abstract In connection with the introduction of hydroxy functions to the C-7 and C-9 positions of anthracycline antitumor antibiotics, 3 such as 4-demethoxydaunomycin (1)3 and of the hetero-anthracyclines such as 4-demethoxy xanthodaunomycin (2), 4-demethoxy thioxantho-daunomycin (3) and 4-demethoxy sulfoxodaunomycin (4), we have discovered that for ...
K. Marat +4 more
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, 2015
The direct hydroxylation of alkanes under mild conditions is a key issue in catalytic chemistry that addresses an increasing number of industrial and economic requirements. Cytochrome P450s are monooxygenases that are capable of oxidizing less reactive C–
Zhiqi Cong +6 more
semanticscholar +1 more source
The direct hydroxylation of alkanes under mild conditions is a key issue in catalytic chemistry that addresses an increasing number of industrial and economic requirements. Cytochrome P450s are monooxygenases that are capable of oxidizing less reactive C–
Zhiqi Cong +6 more
semanticscholar +1 more source
Tryptophan hydroxylation in brain
Biochemical and Biophysical Research Communications, 1964There are several facts suggesting that the first step in the biosynthesis of 5-hydroxytryptamine, the formation of 5-hydroxytryptophan by tryptophan hydroxylation, may occur in brain: 1. 1. There is a rapid turnover of 5-hydroxytryptamine in brain (Udenfriend and Weissbach, 1958); 2. 2. 5-hydroxytryptamine does not freely enter the brain from
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The hydroxylation of nicotine: The origin of the hydroxyl oxygen
Biochemical and Biophysical Research Communications, 1965B.P. Dalton, Lawrence I. Hochstein
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Aromatic Hydroxylation of Estrogens
Annual Review of Physiology, 1983The metabolism of an endogenous steroid hormone has traditionally been viewed as a means of terminating its activity and facilitating its excretion. In recent years, however, examples have accumulated (18,50,76) in which such biotransformations have been shown to have activating rather than inactivating functions, placing the role of metabolism in the ...
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Tryptophan Hydroxylation in Phenylketonuria
1968Publisher Summary To investigate the efficiency of the hydroxylation of tryptophan in phenylketonuria, two adult phenylketonuric patients, and two normal volunteer subjects were given 20 μcuries of L-tryptophan-3-14C intravenously over a 30-minute infusion period.
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Biochemical Acyl Hydroxylations
1972McKenna and Kallio [1] ended their review on the biology of hydrocarbons with a statement which was to prove extremely relevant during the following years: The next review of the subject will have at its disposal the basic data necessary to concern itself not with pathways but rather with a penetrating analysis of mechanism at the molecular and ...
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