Results 101 to 110 of about 189,846 (385)

Synthesis and biological investigation of (+)-3-hydroxymethylartemisinin

Beilstein Journal of Organic Chemistry, 2019
Herein, we describe a biomimetic entry to (+)-3-hydroxymethylartemisinin (2) as well as to the artemisinin derivatives (+)-3-hydroxymethyl-9-desmethylartemisinin (16) and (+)-3-hydroxymethyl-9-epi-artemisinin (18), starting from the known and readily ...
Toni Smeilus, Farnoush Mousavizadeh, Johannes Krieger, Xingzhao Tu, Marcel Kaiser, Athanassios Giannis   +5 more
doaj   +1 more source

Hachimoji DNA and RNA: A genetic system with eight building blocks [PDF]

, 2019
Reported here are DNA and RNA-like systems built from eight (hachi-) nucleotide letters (-moji) that form four orthogonal pairs. This synthetic genetic biopolymer meets the structural requirements needed to support Darwinism, including a polyelectrolyte ...
Bates, Alison M., Benner, Steven A., DasGupta, Saurja, Ellington, Andrew D., Georgiadis, Millie M., Hoshika, Shuichi, Karalkar, Nilesh B., Kim, Hyo-Joong, Kim, Myong-Jung, Kim, Myong-Sang, Leal, Nicole A., Meyer, Adam J., Piccirilli, Joseph A., SantaLucia, Holly A., SantaLucia, John, Jr., Watkins, Norman E., Jr.   +15 more
core   +1 more source

Dual‐Working‐Pattern Nanosheet‐Based Hydrogel Sensors for Constructing Human‐Machine and Physiological‐Electric Interfaces

Advanced Science, EarlyView.
Hydrogels hold great potential as candidates for next‐generation epidermal electronics; however, an unresolved issue remains: the differentiation and selection of sensing modes in hydrogel sensors. This study integrates series‐parallel conductive nanosheet configurations into an ultra‐soft hydrogel, resulting in enhanced signal intensity and ...
Shitao Shi, Yuanyuan Wang, Zewei Ye, Hongxia Xie, Chencong Liu, Jiaqi Liao, Dawei Zhao, Qingfeng Sun, Julia L. Shamshina, Xiaoping Shen   +9 more
wiley   +1 more source

Efficient Red Light–Driven Singlet Oxygen Photocatalysis with an Osmium‐Based Coulombic Dyad

Angewandte Chemie, EarlyView.
Red light‐absorbing bichromophores with straightforward preparation and superior photocatalytic activity were developed. Spectroscopic studies provided deep insights into the intra‐ion‐pair energy transfer key step and the novel approach. Abstract Photoactive osmium complexes are widely used sensitizers for the generation of singlet oxygen because they
Matthias Schmitz, Robert Naumann, Katja Heinze, Christoph Kerzig   +3 more
wiley   +2 more sources

Synthesis of 1-azaspiro[4.4]nonan-1-oxyls via intramolecular 1,3-dipolar cycloaddition

Beilstein Journal of Organic Chemistry, 2019
Sterically shielded nitroxides of the pyrrolidine series have shown the highest resistance to reduction. Here we report the synthesis of new pyrrolidine nitroxides from 5,5-dialkyl-1-pyrroline N-oxides via the introduction of a pent-4-enyl group to the ...
Yulia V. Khoroshunova, Denis A. Morozov, Andrey I. Taratayko, Polina D. Gladkikh, Yuri I. Glazachev, Igor A. Kirilyuk   +5 more
doaj   +1 more source

Synthetic routes to Bis-Calix [n]areness : a thesis presented in partial fulfilment of the requirements for the degree of Masterate of Science in Chemistry at Massey University [PDF]

, 1997
The literature procedures for the targeted syntheses of p-tert-butylcalix[4]arene, p-tert-butylcalix[5]arene, p-tert-butylcalix[6]arene, p-tert-butylcalix[7]arene, and p-tert-butylcalix[8]arene have been repeated successfully.
Irwin, Jacob Lawrence
core  

Luddin type anthraquinone glycosides from Putoria calabrica [PDF]

, 2002
Two new lucidin type anthraquinone glycosides, putorinoside A (1) and putorinoside B (2) were isolated from Putoria calabrica, in addition to two known anthraquinone glycosides, lucidin 3-O-β-glucopyranoside (3) and lucidin 3-O-primeveroside (4).
Chris M. Ireland, Deniz Tasdemir, Ihsan Çalis, LINDEN A, Otto Sticher   +4 more
core   +1 more source

Symmetry Breaking of Molecules Triggered by Chiral Inorganic Nanostructures Without Organic Components

Advanced Science, EarlyView.
Chiral nano‐inorganics, free of organic chiral ligands, provide a novel platform to direct symmetry breaking in molecular systems, through inorganic‐to‐organic chirality transfer via enantiospecific inorganic–organic interactions, circularly polarized light, and electron spin‐driven enantiopreferential reactions governed by chiral‐induced spin ...
Tao Yao, Xiao Chen, Yating Fang, Zhifeng Huang   +3 more
wiley   +1 more source

Regioselective C─H Functionalization by the Combination of Enzymatic and Chemocatalytic Reactions in Water

Angewandte Chemie, EarlyView.
H3CP contributes to sustainable synthesis by integrating regioselective enzymatic halogenation, Pd‐catalyzed Heck coupling, and enzymatic hydrolysis. TPGS‐705‐M micelles enable the Pd‐catalyzed step, allowing seamless compatibility with enzymatic reactions in one vessel under aqueous conditions.
Ran Zhu, Xuhua Mo, Tanja Gulder, Tobias A. M. Gulder   +3 more
wiley   +2 more sources

Solvent and thermal stability, and pH kinetics, of proline-specific dipeptidyl peptidase IV-like enzyme from bovine serum [PDF]

, 2007
Proline-specific dipeptidyl peptidase-like (DPP IV; EC 3.4.14.5) activity in bovine serum has attracted little attention despite its ready availability and the paucity of useful proline-cleaving enzymes.
Abbott, Barry, Brendan F. O’Connor, Buckley, Bušek, Chruscinska, Ciarán Ó’Fágáin, De Meester, Deborah M. Ruth, Demuth, Dixon, Duke-Cohan, Dunn, Durinx, Edens, Engel, Fersht, FitzGerald, Gonzalez, Gorren, Grasso, Jagath, Khmelnitsky, Kikkawa, Lambeir, Lee, Maes, Mentlein, Mittal, Ogino, Ohkubo, Ohnishi, O’Cuinn, Poltorak, Poltorak, Rasmussen, Sears, Sentandreu, Sheehan, Smith, Séamus J. Buckley, Trubetskoy, Yaron, Yoshimoto   +43 more
core   +1 more source