Results 111 to 120 of about 350,851 (339)

Multicatalytic Access to Renewable Poly(Silyl Ether)s with Tunable Properties

Angewandte Chemie, EarlyView.
This work presents a one‐pot, multicatalytic approach that combines magnesium‐catalyzed esterification and borane‐mediated hydrosilylation for the synthesis of partially bio‐based poly(silyl ethers). This method allows for the tuning of thermal and mechanical properties, including exceptional extensibility (>3800%), and enables efficient chemical ...
Fan Yang, Fan Sun, Christophe M. Thomas
wiley   +2 more sources

Cynaratriol, a sesquiterpene lactone from Centaurea musimomum

Acta Crystallographica Section E, 2009
The title compound [systematic name: 3,8-dihydroxy-3-(hydroxymethyl)-9-methyl-6-methylenedecahydroazuleno[4,5-b]furan-2(3H)-one], C15H22O5, is a sesquiterpene lactone showing the typical tricyclic guaianolide skeleton which has been isolated, together ...
Matías López-Rodríguez, Victor P. García, Hanêne Zater, Samir Benayache, Fadila Benayache   +4 more
doaj   +1 more source

A Programmable Nanoreactor Orchestrates Cascade of DNA Sensing to Amplify cGAS‐STING Activation for Cancer Immunotherapy

Advanced Science, EarlyView.
A programmable nanoreactor was engineered for precise cGAS‐STING pathway activation in cancer immunotherapy. This strategy bridges targeted tumor DNA damage with DC immunomodulation, providing a translatable platform to unlock innate and adaptive antitumor immunity.
Shuang Liang, Yiwei Tian, Feiyu Zhao, Yue Han, Kongshuo Ma, Linna Hai, Kaiqing Yun, Yueyang Zhao, Siqi Zhang, Ziyi Zhang, Yuxuan Peng, Kuan Hu, Jing Zhong, Bai Xiang, Zhaohui Wang   +14 more
wiley   +1 more source

Total Synthesis of (+)‐Melonine and (+)‐N4‐Oxy Melonine Enabled by an Intramolecular Alkene Diamination Reaction

Angewandte Chemie, EarlyView.
A complexity‐generating intramolecular alkene diamination constitutes the pivotal step in the enantioselective synthesis of the title natural products featuring a strained, cage‐like pentacyclic architecture. Abstract Among more than four thousand monoterpene indole alkaloids (MIAs) isolated to date, only a few feature a 2,2,3‐trisubstituted indoline ...
Vincent Goëlo, Qian Wang, Jieping Zhu
wiley   +2 more sources

(S)-2,2′-Dihydroxy-N,N′-(6-hydroxyhexane-1,5-diyl)dibenzamide

Acta Crystallographica Section E, 2013
In the title compound, C20H24N2O5, the dihedral angle between the two roughly planar salicylamide fragments [r.m.s. deviations = 0.043 (2) and 0.149 (2) Å] is 25.50 (5)°.
Sabine Wilbrand, Christian Neis, Kaspar Hegetschweiler   +2 more
doaj   +1 more source

Disruption of vitamin A homeostasis by the biocide tetrakis(hydroxymethyl) phosphonium sulphate in pregnant rabbits [PDF]

, 2022
Natalia Estrada‐Ortiz, Viktoriia Starokozhko, Hidde van Steenwijk, Cor van der Heide, Hjalmar P. Permentier, Lisanne van Heemskerk, Grietje H. Prins, Janette Heegsma, Klaas Nico Faber, Steffi Bressers, Guy Steiblen, Antoinette de Groot, Steve Groome, Erik Van Miert, Geny M. M. Groothuis, Inge A.M. de Graaf   +15 more
openalex   +1 more source

Mineralized Cryogel/Hydrogel Constructs to Recapitulate Early Breast Cancer Bone Metastasis In Vitro

Advanced Science, EarlyView.
A new biphasic in vitro cryogel/hydrogel model of early breast cancer bone metastasis provides precise control over microenvironmental cues and microscopic access to the spatiotemporal cancer cell distribution. Deposited bone‐like mineral is observed to strongly impede the effects of biomolecular signals, as evidenced by both colonization profiles and ...
Jana Sievers‐Liebschner, Petra B. Welzel, Maximilian Fusenig, Linda Sturm, Dagmar Pette, Wolfgang Wagermaier, Claudia Fischbach, Peter Fratzl, Carsten Werner   +8 more
wiley   +1 more source

X-ray Crystallographic Characterization of the Co(II)-substituted Tris-bound Form of the Aminopeptidase from \u3cem\u3eAeromonas proteolytica\u3c/em\u3e [PDF]

, 2007
The X-ray crystal structure of the Co(II)-loaded form of the aminopeptidase from Aeromonas proteolytica ([CoCo(AAP)]) was solved to 2.2 Å resolution. [CoCo(AAP)] folds into an α/β globular domain with a twisted β-sheet hydrophobic core sandwiched between
Bennett, Brian, Holz, Richard C., Moulin, Aaron, Munih, Petra, Petsko, Gregory A., Ringe, Dagmar, Stamper, Carin   +6 more
core   +1 more source

Accessing decavanadate chemistry with tris(hydroxymethyl)aminomethane, and evaluation of methylene blue bleaching [PDF]

, 2020
Juliana Morais Missina, Luiza B.P. Leme, Kahoana Postal, Francielli S. Santana, David L. Hughes, Eduardo L. de Sá, Ronny R. Ribeiro, Giovana G. Nunes   +7 more
openalex   +1 more source

Clickable Microgel Inks Enable Spatioselective, Multi‐Stimuli Programmable Assembly of Materials

Advanced Science, EarlyView.
Clickable microgel inks enable direct ink writing of hydrogel architectures with intrinsic spatioselective and programmable multi‐responsiveness. By combining pH‐responsive and temperature‐responsive microgel building blocks through Diels‐Alder interparticle crosslinking, the assemblies exhibit controllable swelling and shape changes.
Junho Moon, Frank Gardea, Madeline A. Morales, Svetlana Sukhishvili   +3 more
wiley   +1 more source