Results 181 to 190 of about 142,060 (347)

Inhibition of the clathrin terminal domain – amphiphysin protein‐protein interaction. Probing the Pitstop® 2 aromatic moiety.

open access: yesChemMedChem, Accepted Article.
Pitstop 2, (Z)‐N‐(5‐(4‐bromenzylidene)‐4‐oxo‐4,5‐dihydrothiazol‐2‐yl)naphthalene‐1‐sulfonamide (1), inhibits the clathrin terminal domain‐ amphiphysin interaction (NTD‐PPI) and has been widely used to investigate endocytosis. In this work we report on the synthesis of 56 novel Pitstop 2 analogues via four discrete focused libraries.
Kate Prichard   +10 more
wiley   +1 more source

THE SYNTHESES OF 1- [[2- AMINO -1 - (HYDROXYMETHYL) ETHOXY] METHYL] URACIL AND 1, 3-BIS (2- HALOETHOXYMETHYL) PYRIMIDINE [PDF]

open access: yesJournal of Sciences, Islamic Republic of Iran, 1990
The syntheses of the title compounds are described. 1- [[2- Amino -1 - (hydroxymethyl) ethoxy] methyl] uracil exhibitslittleactivity against herpesviruses (HSV) in ...
doaj  

Determination of Diketopiperazine Formation During the Solid‐Phase Synthesis of C‐Terminal Acid Peptides

open access: yesChemistry–Methods, EarlyView.
Diketopiperazine formation (DKP) is one of the most serious side reactions during peptide synthesis. An accurate method to determine the DKP formation in peptide synthesis on Wang resin is reported. Furthermore, the strategies to minimize this side reaction and side products lacking C‐terminal amino acids are described. Diketopiperazine formation (DKP)
Mani Kaushal   +7 more
wiley   +1 more source

Computational Evaluation of Redox Potentials of Metal Complexes for Aqueous Flow Batteries

open access: yesChemPhysChem, EarlyView.
Experimental and computational screening of redox potentials of several metal complexes is done. Computationally a large set of metal and ligand combinations has been studied. M = Fe,Ni,Ti,Mn, ligands include PIB, EDTA, cathecol, terpy, DIPSO. Most of the ligands are modified with functional groups. Flow batteries are a promising option for large‐scale
Aliyeh Mehranfar   +7 more
wiley   +1 more source

En Route Toward Sustainable Polycarbonates via Large Cyclic Carbonates

open access: yesChemSusChem, EarlyView.
The use of safe carbonylating agents, allowed by a suitable (bio)catalytic systems, affords the sustainable and green synthesis of large‐ring cyclic carbonates by reaction of renewables such as bio‐based diols. These carbonates are prone to ring‐opening polymerization paving the way for the production of circular aliphatic polycarbonates.
Francesco Della Monica   +5 more
wiley   +1 more source

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