Results 11 to 20 of about 385,761 (370)

Inhibition of sterol biosynthesis in animal cells by 14 alpha-hydroxymethyl sterols.

Journal of Lipid Research, 1980
The chemical syntheses of a number of 14 alpha-hydroxymethyl sterols and 14 alpha -hydroxymethyl-15 alpha-hydroxysterols and their derivatives have been pursued to permit evaluation of their activity in the inhibition of sterol biosynthesis in animal ...
G J Schroepfer, Jr, E J Parish, R A Pascal, Jr, A A Kandutsch   +3 more
doaj   +1 more source

Treatment of severe metformin-associated lactic acidosis with renal replacement therapy and tris-hydroxymethyl aminomethane: a case report

Journal of Medical Case Reports, 2023
Background Type B lactic acidosis is a rare but serious side effect of metformin use. The risk of metformin-associated lactic acidosis is elevated in renal or liver impairment, heart failure and in metformin overdose. Metformin-associated lactic acidosis
Diana Yusim, Bogdan Tiru, Marat Abdullin, Daniel L. Landry, Spencer Hodgins, Gregory L. Braden   +5 more
doaj   +1 more source

Fluorescent property of 3-hydroxymethyl imidazo[1,2-a]pyridine and pyrimidine derivatives

Chemistry Central Journal, 2012
Background Imidazo[1,2-a]pyridines and pyrimidines are important organic fluorophores which have been investigated as biomarkers and photochemical sensors.
Velázquez-Olvera Stephania, Salgado-Zamora Héctor, Velázquez-Ponce Manuel, Campos-Aldrete Elena, Reyes-Arellano Alicia, Pérez-González Cuauhtémoc   +5 more
doaj   +1 more source

A surprising steric effect on a tandem cycloaddition/ring-opening reaction : rapid syntheses of difluorinated analogues of (hydroxymethyl)conduritols [PDF]

, 2004
Difluorinated analogues of (hydroxymethyl)conduritols can be synthesised from selected furans and a difluorinated dienophile in two reaction ...
Fawcett, J., Hillier, I.H., Moralee, A.C., Percy, Jonathan, Salafia, Vittoria, Vincent, M.A.   +5 more
core   +1 more source

Sterol synthesis. A simplified method for the synthesis of 32-oxygenated derivatives of 24,25-dihydrolanosterol.

Journal of Lipid Research, 1981
A simplified method is described for the preparation of 14 alpha-hydroxymethyl-4,4-dimethyl-5 alpha-cholest-8-en-e beta-ol, 14 alpha-hydroxymethyl-4,4-dimethyl-5 alpha-cholest-7-en-3 beta-ol, and 14 alpha-hydroxymethyl-4,4-dimethyl-5-alpha-cholest-6-en-3
E J Parish, G J Schroepfer, Jr
doaj   +1 more source

Synthetic strategies for preparing BEDT-TTF derivatives functionalised with metal ion binding groups [PDF]

, 2006
The syntheses of BEDT-TTF (ET) derivatives with potential metal ion binding pyridyl, bipyridyl and terpyridyl groups are achieved either by stepwise construction of the organosulfur core or via reactions of hydroxymethyl-ET for which a cheap and ...
Alberola, Allen, Anderson, Avarvari, Chahma, Constable, Cook, Coronado, Coronado, Coronado, Day, Devic, Devic, Dumont, Fallahpour, Fletcher, Griffiths, Griffiths, Hui Nie, Iwahori, John D. Wallis, Jon-Paul Griffiths, Karrer, Kini, Kobayashi, Kobayashi, Kurmoo, Li, Mas-Torrent, Matsumiya, Ota, Ouahab, Ouahab, Peter Day, Qiang Wang, R?thor?, Saygili, Setifi, Setifi, Setifi, Setifi, Setifi, Setifi, Singleton, Singleton, Smucker, Svenstrup, Tanaka, Taniguchi, Turner, Turner, Turner, Uenishi, Uji, Wang, Wenkert, Whangbo, Williams, Xu, Zambounis, Zhang   +60 more
core   +1 more source

Synthesis, Chemistry and Applications of 5-Hydroxymethyl-furfural And Its Derivatives [PDF]

, 2001
The prospect of exciting research activity in the chemistry of furfural derived compounds such as 5-hydroxymethylfurfural (HMF), 2,5-furandicarbaldehyde and 2,5-furan-dicarboxylic acid prompted the writing of this article.
Lewkowski, Jarosław
core   +1 more source

Synthese und Eigenschaften von (Hydroxymethyl)dimethylgerman und (Hydroxymethyl)diphenylgerman [PDF]

Journal of Organometallic Chemistry, 1988
Abstract Starting from GeCl4, the (hydroxymethyl)diorganylgermanes (CH3)2Ge(H)CH2OH and (C6H52Ge(H)CH2OH were prepared by a four-step synthesis in total yields of 15 and 32%, respectively (GeCl4 → Cl3GeCH2Cl → R2Ge(Cl)CH2Cl → R2Ge(OAc)CH2OAc → R2Ge(H)CH2OH; R  CH3 or C6H5).
Tacke, Reinhold, Becker, B.
openaire   +1 more source

The Anti-HIV Actions of 7- and 10-Substituted Camptothecins

Molecules, 2009
Camptothecin (CPT), a traditional anti-tumor drug, has been shown to possess anti-HIV-1 activity. To increase the antiviral potency, the anti-HIV activities of two CPT derivatives, 10-hydroxy-CPT and 7-hydroxymethyl-CPT, were evaluated in vitro.
Yu-Ye Li, Shi-Wu Chen, Liu-Meng Yang, Rui-Rui Wang, Wei Pang, Yong-Tang Zheng   +5 more
doaj   +1 more source

Freezing-tolerant and robust gelatin-based supramolecular conductive hydrogels with double-network structure for wearable sensors

Polymer Testing, 2021
It is significant to design stretchable conductive hydrogels with high integrated mechanical and excellent anti-freezing performances for broadening their application fields. Herein, a freezing-tolerant and robust poly(N-hydroxymethyl acrylamide)/gelatin/
Jia Yang, Xiangbin Sun, Qiong Kang, Lin Zhu, Gang Qin, Qiang Chen   +5 more
doaj   +1 more source