Results 311 to 320 of about 350,851 (339)
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1,8-Bis(hydroxymethyl)anthracene
Acta Crystallographica Section C Crystal Structure Communications, 1997Anthracene-1,8-dimethanol, C16H14O2, crystallized in the centrosymmetric space group P21/n. The anthracene core is nearly planar and shows good agreement with the anthracene core of anthracene-1,8-dicarboxylic acid. The geometric disposition of the hydroxymethyl groups and the values of the hydrogen-bond parameters are strikingly similar to those in ...
W D, Aumiller, R E, Gerkin
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General Pharmacology: The Vascular System, 1997
1. The N-(hydroxymethyl) melamines are analogs of the antitumor agent hexamethylmelamine (HMM) which do not require bioactivation to exert their antitumor effects. 2. Trimelamol (N2,N4,N6-trihydroxymethyl-N2,N4,N6-trimethylmelamine; TM) was developed as a water-soluble antitumor agent for intravenous administration. 3.
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1. The N-(hydroxymethyl) melamines are analogs of the antitumor agent hexamethylmelamine (HMM) which do not require bioactivation to exert their antitumor effects. 2. Trimelamol (N2,N4,N6-trihydroxymethyl-N2,N4,N6-trimethylmelamine; TM) was developed as a water-soluble antitumor agent for intravenous administration. 3.
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Hydroxymethylated DNA Immunoprecipitation (hmeDIP)
20135-hydroxymethylcytosine (5hmC) was recently identified as an abundant epigenetic mark in mammals. Subsequent research has implicated 5hmC in normal mammalian development and disease pathogenesis in humans. Many of the techniques commonly used to assay for canonical 5-methylcytosine (5mC) cannot distinguish between 5hmC and 5mC.
Colm E, Nestor, Richard R, Meehan
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Trialkylsilylmethyltris(hydroxymethyl)methanes
Bulletin of the Academy of Sciences of the USSR Division of Chemical Science, 1989Trialkylsilylmethyltris (hydroxymethyl) methanes were synthesized by the reaction of β-trialkylsilylpropanals with formaldehyde.
A. K. Ustinov +2 more
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α.α‐Bis‐hydroxymethyl‐butyraldehyd und α.α‐Bis‐hydroxymethyl‐buttersäure
Chemische Berichte, 1962AbstractDie α.α‐Bis‐hydroxymethyl‐alkanale bilden ohne H⊕‐Ionenkatalyse spontan die durch Wasserstoffbrückenbindungen stabilisierten Paraldehyde. Ihre Bildungstendenz nimmt mit steigendem Molekulargewicht ab. Bei der Oxydation zu den Bis‐hydroxymethyl‐carbonsäuren stört die Retro‐Aldolisierung. Überraschenderweise gelang es, Buttersäure mit Formaldehyd
Otto Neunhoeffer, Hans Neunhoeffer
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Hydroxymethylation of rhodanine
Russian Journal of General Chemistry, 2010Rhodanine in alcohol solution reacts with formaldehyde aqueous solution to form 3-hydroxymethylrhodanine. In the presence of triethylamine occurred also bis-hydroxymethylation at 5 position of the thiazolidine ring, but we failed to isolate the 3,5,5-trishydroxymethyl derivative in an individual form.
Sun Min’yan’ +3 more
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Justus Liebigs Annalen der Chemie, 1964
Abstractα‐Hydroxymethyl‐tropasäuretropylester wird durch Schmelzen von Tropin‐hydrochlorid mit α.α‐Bis‐acetoxymethyl‐phenylessigsäurechlorid erhalten. Als Nebenprodukt tritt 3‐Chlor‐tropan auf. α‐Hydroxymethyl‐tropasäuretropylester zeigt im biologischen Versuch eine geringere Aktivität als (‐)‐α‐Methyltropasäuretropylester.
Emilio Testa, Luigi Fontanella
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Abstractα‐Hydroxymethyl‐tropasäuretropylester wird durch Schmelzen von Tropin‐hydrochlorid mit α.α‐Bis‐acetoxymethyl‐phenylessigsäurechlorid erhalten. Als Nebenprodukt tritt 3‐Chlor‐tropan auf. α‐Hydroxymethyl‐tropasäuretropylester zeigt im biologischen Versuch eine geringere Aktivität als (‐)‐α‐Methyltropasäuretropylester.
Emilio Testa, Luigi Fontanella
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HYDROXYMETHYLATION OF FLAVONES
Organic Preparations and Procedures International, 1991(1991). HYDROXYMETHYLATION OF FLAVONES. Organic Preparations and Procedures International: Vol. 23, No. 6, pp. 741-747.
György Litkei +3 more
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Bis(hydroxymethyl)phosphine Oxides and Hydroxymethyl Phosphinic Acids as Phosphonic Acid Analogs
Phosphorus, Sulfur, and Silicon and the Related Elements, 2002(2002). Bis(hydroxymethyl)phosphine Oxides and Hydroxymethyl Phosphinic Acids as Phosphonic Acid Analogs. Phosphorus, Sulfur, and Silicon and the Related Elements: Vol. 177, No. 8-9, pp. 2221-2222.
Pirat, Jean-Luc +5 more
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Dynamics of DNA Hydroxymethylation in Zebrafish
Zebrafish, 2015During embryonic development in mammals, most of the methylated cytosines in the paternal genome are converted to 5-hydroxymethyldeoxycytidine (hmC), as part of DNA methylation reprogramming. Recent data also suggest tissue-specific functional roles of hmC, perhaps as an epigenetic mark.
Kamstra, Jorke H. +3 more
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