Results 331 to 340 of about 142,060 (347)

Hydroxymethylation and cyanoethylation of nitroimidazoles

Journal of Heterocyclic Chemistry, 1979
AbstractA series of nitroimidazoles were subjected to hydroxymethylations under a variety of conditions. Hydroxymethylation of 1‐(2‐hydroxyethyl), 1‐(2‐acetoxyethyl), and 1‐(2‐chloroethyl) substituted 5‐nitroimidazoles with paraformaldehyde in dimethyl sulfoxide yielded the respective 2‐hydroxymethyl analogs (5–7). However, attempts to hydroxymethylate
Raj K. Sehgal, Krishna C. Agrawal
openaire   +2 more sources

Hydroxymethylated DNA Immunoprecipitation (hmeDIP)

2013
5-hydroxymethylcytosine (5hmC) was recently identified as an abundant epigenetic mark in mammals. Subsequent research has implicated 5hmC in normal mammalian development and disease pathogenesis in humans. Many of the techniques commonly used to assay for canonical 5-methylcytosine (5mC) cannot distinguish between 5hmC and 5mC.
Richard R. Meehan, Colm E. Nestor, Colm E. Nestor   +2 more
openaire   +3 more sources

The Preparation of Tri(hydroxymethyl)Sulfanilamidomethane

Journal of the American Pharmaceutical Association (Scientific ed.), 1948
Tri (hydroxymethyl) sulfanilamidomethane was prepared by treating tri(hydroxymethyl)-aminomethane with p-acetoaminobenzenesulfonyl chloride in an aqueous medium with controlled temperature and subsequent hydrolysis of the acetyl compound. Proof of the presence of three hydroxyl groups in the molecule was accomplished by acetylation and subsequent ...
James W. Jones, Gail A. Wiese
openaire   +3 more sources

Bis(hydroxymethyl)phosphine Oxides and Hydroxymethyl Phosphinic Acids as Phosphonic Acid Analogs

Phosphorus, Sulfur, and Silicon and the Related Elements, 2002
(2002). Bis(hydroxymethyl)phosphine Oxides and Hydroxymethyl Phosphinic Acids as Phosphonic Acid Analogs. Phosphorus, Sulfur, and Silicon and the Related Elements: Vol. 177, No. 8-9, pp. 2221-2222.
Christine Brahic, Jean-Luc Pirat, David Virieux, Henri-Jean Cristau, Agnes Herve, Ciptadi Ciptadi   +5 more
openaire   +2 more sources

DNA Methylation and Hydroxymethylation and Behavior

2019
Environmentally sensitive molecular mechanisms in the brain, such as DNA methylation, have become a significant focus of neuroscience research because of mounting evidence indicating that they are critical in response to social situations, stress, threats, and behavior.
Ligia A. Papale, Sarah R. Rustad, Reid S. Alisch   +2 more
openaire   +3 more sources

Hydroxymethylation of Oxindoles

Synfacts, 2010
Y.-H. Liao, X.-M. Zhang, X.-L. Liu, L.-F. Cun, W.-C. Yuan, Z.-J. Wu   +5 more
openaire   +2 more sources

Demethylation and hydroxymethylation in the mouse zygote

2012
In the mouse zygote, DNA methylation patterns undergo important changes and differ in the maternal and paternal pronucleus. Demethylation of the paternal genome has been described as an active and replication-independent process, although the mechanisms responsible for it are not yet fully understood.
Salvaing, Juliette, Aguirre-Lavin, Tiphaine, Boulesteix, Claire, Lehmann, Gaetan, Debey, Marie Pascale, Beaujean, Nathalie   +5 more
openaire   +2 more sources

Controlled hydroxymethylation of ketones

The Journal of Organic Chemistry, 1971
E. J. Corey, David E. Cane
openaire   +2 more sources

Mechanisms of formylation and hydroxymethylation reactions [PDF]

Journal of Cellular and Comparative Physiology, 1959
M. J. Osborn, H.R. Whiteley, F.M. Huennekens   +2 more
openaire   +2 more sources

Structure elucidation of mono-(hydroxymethyl)- and di-(hydroxymethyl)-3-hydroxypyridines

Journal of Chromatography A, 1966
openaire   +3 more sources