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Measures of hydroxymethylation
Hydroxymethylcytosine (5hmC) methylation is known to be a possible epigenetic mark impacting genome stability. In this paper, we address the existing 5hmC measure $ $ and discuss its properties both analytically and empirically on real data. Then we introduce several alternative hydroxymethylation measures and compare their properties with those of $
Slynko, Alla, Benner, Axel
openaire +2 more sources
Synthese und Eigenschaften von (Hydroxymethyl)dimethylgerman und (Hydroxymethyl)diphenylgerman [PDF]
Abstract Starting from GeCl4, the (hydroxymethyl)diorganylgermanes (CH3)2Ge(H)CH2OH and (C6H52Ge(H)CH2OH were prepared by a four-step synthesis in total yields of 15 and 32%, respectively (GeCl4 → Cl3GeCH2Cl → R2Ge(Cl)CH2Cl → R2Ge(OAc)CH2OAc → R2Ge(H)CH2OH; R CH3 or C6H5).
Tacke, Reinhold, Becker, B.
openaire +1 more source
A copper complex of an unusual hydroxy–carboxylate ligand: [Cu(bpy)(C4H4O6)]
A copper(II) complex, (2,2′-bipyridine-κ2N,N′)[2-hydroxy-2-(hydroxymethyl-κO)propanedioato-κ2O1,O3]copper(II), [Cu(C4H4O6)(C10H8N2)], containing the unusual anionic chelating ligand 2-(hydroxymethyl)tartronate, has been synthesized.
Sen Gao+2 more
doaj +1 more source
Influence of water on localized and delocalized molecular mobility of cellulose [PDF]
The influence of hydration on cellulose molecular mobility is investigated by two dielectric methods at different molecular scale. The mobility of side groups, assigned to c mode, for dried cellulose increases.
Boudet, Alain-Michel+4 more
core +1 more source
NEW N-GLUCOSYLATED SUBSTITUTED ANILINES [PDF]
The reaction of (+)-D-glucose with 4-chloroaniline or 3,5-dibromoaniline leads almost exclusively to the β-configuration of glucosylated anilines. The acetylating of 2-(3,5-dibromophenylamino)-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol is less ...
Vsevolod Pogrebnoi
doaj
Synthesis and Anti-Hepatitis B Activities of 3′-Fluoro-2′-Substituted Apionucleosides
Nucleoside analogues have excellent records as anti-HBV drugs. Chronic infections require long-term administration ultimately leading to drug resistance. Therefore, the search for nucleosides with novel scaffolds is of high importance. Here we report the
Martin Holan+7 more
doaj +1 more source
Polyoxometalate (POM)-layered double hydroxides (LDH) composite materials: design and catalytic applications [PDF]
Layered double hydroxides (LDHs) are an important large class of two-dimensional (2D) anionic lamellar materials that possess flexible modular structure, facile exchangeability of inter-lamellar guest anions and uniform distribution of metal cations in ...
Li, Tengfei+2 more
core +1 more source
The sustainable synthesis of two important intermediates relevant for the production of bio-based polymers, 2,5-furandicarboxylic acid (FDCA) and 5-hydroxymethyl-2-furancarboxylic acid (HFCA), via oxidation of 5-(hydroxymethyl)furfural (HMF) was ...
O. Schade+4 more
semanticscholar +1 more source
In contrast to the well-studied crystalline cellulose of microbial and animal origins, cellulose in plant cell walls is disordered due to its interactions with matrix polysaccharides.
Pyae Phyo+4 more
semanticscholar +1 more source
Joule‐assisted nanotherapeutic urethral stent harnesses a smart, biodegradable magnesium stent to orchestrate spatiotemporal theragenerative therapy for urethral strictures. Magnetically induced Joule heating enables on‐demand drug release and bacterial ablation, while simultaneously guiding urothelial regeneration.
Yuhyun Na+15 more
wiley +1 more source