Recent updates in dyslipidemia management: perspectives in stroke-specific situation [PDF]
Precision and Future Medicine, 2020 Managing dyslipidemia in stroke is essential. During the past several decades, monumental changes in dyslipidemia management have occurred, resulting in improvement in outcomes of patients with cardiovascular disease (CVD).
Woo-Keun Seo +3 more
doaj +1 more source
Effect of atorvastatin on systolic and diastolic function in patients with heart failure with reduced ejection fraction (HFrEF) [PDF]
Medicinski Glasnik, 2021 Aim To investigate the benefit of high-dose lipophilic statin therapy on cardiac remodelling, function and progression of heart failure (HF) in patients with ischemic heart disease.
Faris Zvizdić +4 more
doaj +1 more source
Rhamnetin decreases the expression of HMG-CoA reductase gene and increases LDL receptor in HepG2 cells [PDF]
Journal of Pharmacy & Pharmacognosy Research, 2023 Context: Rhamnetin is a naturally occurring methylated derivative of quercetin. This flavonoid is abundant in Syzygium aromaticum, Coriandrum sativum Prunus cerasus, and Rhamnus spp.
Raghad R. Al-Yousef +3 more
doaj +1 more source
Hypolipidemic effects of total flavonoide extracted from the leaves of Actinidia kolomikta in rats fed a high-fat diet [PDF]
Iranian Journal of Basic Medical Sciences, 2017 Objective(s): This study was to investigate the antihyperlipidemic and antioxidant effect of total flavonoid extract from Actinidia kolomikta (TFAK) in hyperlipidemia induced by a high-fat diet.
Zhenxiang Yu +4 more
doaj +1 more source
Statin-induced myopathic changes in primary human muscle cells and reversal by a prostaglandin F2 alpha analogue [PDF]
, 2020 Statin-related muscle side effects are a constant healthcare problem since patient compliance is dependent on side effects. Statins reduce plasma cholesterol levels and can prevent secondary cardiovascular diseases.
Dittmar, Gunnar +10 more
core +1 more source
Revista Portuguesa de Medicina Geral e Familiar, 2020 Objetivo: Determinar o impacto da redução intensiva do c-LDL com estatina na morbimortalidade nos utentes com diabetes. Métodos: Foi realizada uma pesquisa de artigos em inglês, publicados entre 1 de janeiro de 2008 e 19 de Julho de 2018, com os termos:
Carla Longras +2 more
doaj +1 more source
Journal of Lipid Research, 1975 In skin fibroblasts grown from four children with a homozygous form of type II hyperlipoproteinemia, the feedback control of sterol synthesis and the inhibitory effect on hydroxymethylglutaryl (HMG) CoA reductase activity by serum or low density ...
J. Avigan, S.J. Bhathena, M.E. Schreiner
doaj +1 more source
Influence of anti-hyperlipidemic activity by co-administration of polyamines and rutin with simvastatin [PDF]
Journal of HerbMed Pharmacology, 2023 Introduction: Natural polyphenols, rutin, endogenous polycations, and polyamines (spermine and spermidine) are reported to have beneficial effects on hyperlipidemia, obesity, and cardiovascular disease (CVD).
Rajesh R Patil +3 more
doaj +1 more source
Hydroxymethylglutaryl-CoA reductase inhibition with simvastatin in acute lung injury to reduce pulmonary dysfunction (HARP-2) trial : study protocol for a randomized controlled trial [PDF]
, 2012 Acute lung injury (ALI) is a common devastating clinical syndrome characterized by life-threatening respiratory failure requiring mechanical ventilation and multiple organ failure.
A Mercat +31 more
core +1 more source
Statins as Antifungal Agents: A Review on Drug Repurposing and Nanotechnology-Driven Delivery Strategies. [PDF]
Fundam Clin PharmacolABSTRACT This review highlights the integration of drug repurposing and nanotechnology‐driven delivery strategies as innovative approaches to enhance the antifungal activity of statins against mucosal candidiasis, providing a framework for future translational research and clinical application.
E Silva DM +8 more
europepmc +2 more sources