Results 191 to 200 of about 16,480 (226)
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Adenosine monophosphate-activated protein kinase: hydroxymethylglutaryl-CoA reductase kinase.
Methods in enzymology, 1991Hydroxymethylglutaryl-CoA (HMG-CoA) reductase kinase has been previously assayed by its ability to inactivate HMG-CoA reductase in crude rat liver microsomes, using a radioisotopic assay for HMG-CoA reductase. However, this assay is insensitive and time consuming and it uses expensive radioisotopes and is subject to interference by HMG-CoA lyase and ...
Carling, D, Clarke, PR, Hardie, DG
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Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism, 1978
Hydroxymethylglutaryl-CoA reductase activity in fasting rats was almost doubled 12 h following a single dose (400 mg/kg) of the porphyrogenic chemical allylisopropylacetamide. This doubling effect of the drug on enzyme activity was observed during the basal period, as well as at midnight, when it is maximal in the diurnal rhythm. Cycloheximide, whether
A, Sanghvi, B, Parikh
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Hydroxymethylglutaryl-CoA reductase activity in fasting rats was almost doubled 12 h following a single dose (400 mg/kg) of the porphyrogenic chemical allylisopropylacetamide. This doubling effect of the drug on enzyme activity was observed during the basal period, as well as at midnight, when it is maximal in the diurnal rhythm. Cycloheximide, whether
A, Sanghvi, B, Parikh
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The Natural Products as Hydroxymethylglutaryl-Coa Reductase Inhibitors
High cholesterol and triglyceride levels are mainly related to further generation of life-threating metabolism disorders including cardiovascular system diseases. Therefore, hypercholesterolemia (i.e., also referred to as hyperlipoproteinemia) is a serious disease state, which must be controlled.Gulcan, Hayrettin Ozan +2 more
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Cancer biochemistry biophysics, 1988
Cholesterol synthesis and 3-hydroxy-3-methylglutaryl CoA reductase (HMG-CoA reductase) in the liver of rats at various times (7, 22, 45 and 314 days) after injection with the carcinogen, methylazoxymethanol acetate (MAMA) is reported. Seven days after treatment, an increase in both cholesterol synthesis and HMG-CoA reductase activity was observed ...
Gregg R.G., Wilce P.A.
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Cholesterol synthesis and 3-hydroxy-3-methylglutaryl CoA reductase (HMG-CoA reductase) in the liver of rats at various times (7, 22, 45 and 314 days) after injection with the carcinogen, methylazoxymethanol acetate (MAMA) is reported. Seven days after treatment, an increase in both cholesterol synthesis and HMG-CoA reductase activity was observed ...
Gregg R.G., Wilce P.A.
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Hydroxymethylglutaryl-CoA reductase (NADPH)
1995Dietmar Schomburg, Dörte Stephan
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[Hydroxymethylglutaryl-CoA reductase (NADPH)]-phosphatase
1991Dietmar Schomburg, Margit Salzmann
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[Hydroxymethylglutaryl-CoA reductase (NADPH)] kinase
1997Dietmar Schomburg, Dörte Stephan
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