Results 71 to 80 of about 16,480 (226)
Journal of Cachexia, Sarcopenia and Muscle, Volume 16, Issue 6, December 2025.ABSTRACT Background Statins are cholesterol‐lowering drugs widely prescribed for preventing cardiovascular diseases. They may cause adverse effects on skeletal muscle, but it remains unclear whether they affect muscle function and mass. We aimed to evaluate the association between statin use and muscle function and mass, and whether the pharmacogenomic
Mélissa Gentreau +6 more
wiley +1 more source
Hypotensive Effects of Statins: A Rapid Review [PDF]
Journal of Clinical and Diagnostic ResearchIntroduction: Recently, hypertension has become a major global health concern that plays a substantial role in morbidity and mortality related to Cardiovascular Disease (CVD).
Smruti Besekar +2 more
doaj +1 more source
Influence of statin use on clinicopathological characteristics of localized prostate cancer and outcomes obtained after radical prostatectomy: a single center study [PDF]
, 2015 To assess the impact of statin use on biochemical recurrence (BCR) of prostate cancer after radical prostatectomy (RP)
Cattarino, Susanna +8 more
core
Andrographis paniculata transcriptome provides molecular insights into tissue-specific accumulation of medicinal diterpenes [PDF]
, 2015 A summary of SSRs identified in leaf and root transcriptomes.
Anchal Garg +4 more
core +8 more sources
British Journal of Pharmacology, Volume 182, Issue 23, Page 5803-5813, December 2025.Background and Purpose Statins are widely prescribed for the prevention of cardiovascular disease, yet recent studies suggest an increased risk of new‐onset Type 2 diabetes mellitus. This study aimed to identify genetic variants associated with statin‐associated new‐onset Type 2 diabetes mellitus from the UK Biobank and All of Us.
Yoon‐A Park +4 more
wiley +1 more source
The effect of statins on psoriasis severity: a meta-analysis of randomized clinical trials
Archives of Medical Science, 2019 Introduction Statins may reduce the severity of psoriasis, but the available evidence is unclear. We conducted a meta-analysis of randomized controlled studies (RCTs) that investigated the effect of statins on psoriasis severity assessed with the ...
Mateusz Socha +6 more
doaj +1 more source
Crystal Structure of a Statin Bound to a Class II Hydroxymethylglutaryl-CoA Reductase
Journal of Biological Chemistry, 2003 Hydroxymethylglutaryl-CoA (HMG-CoA) reductase is the primary target in the current clinical treatment of hypercholesterolemias with specific inhibitors of the "statin" family. Statins are excellent inhibitors of the class I (human) enzyme but relatively poor inhibitors of the class II enzymes of important bacterial pathogens.
Tabernero, Lydia +2 more
openaire +2 more sources
Molecular actions of hypocholesterolaemic compounds from edible mushrooms [PDF]
, 2018 Cholesterol levels are strictly regulated to maintain its homeostasis; therefore, if it is not absorbed with the diet, the cholesterol biosynthetic pathway is enhanced and vice versa.
Gil-Ramírez, Alicia +2 more
core +1 more source
The Concise Guide to PHARMACOLOGY 2025/26: Enzymes
British Journal of Pharmacology, Volume 182, Issue S1, Page S307-S403, December 2025.The Concise Guide to Pharmacology 2025/26 marks the seventh edition in this series of biennial publications in the British Journal of Pharmacology. Presented in landscape format, the guide provides a comparative overview of the pharmacology of drug target families. The concise nature of the Concise Guide refers to the style of presentation, being clear,
Stephen P. H. Alexander +31 more
wiley +1 more source
Journal of Lipid Research, 1983 The effect of 26-hydroxycholesterol and other intermediates in bile acid synthesis on HMG-CoA reductase activity was studied in Chinese hamster ovary (CHO) cell culture.
A L Esterman +3 more
doaj +1 more source