Results 71 to 80 of about 13,154 (208)

Simvastatin decreases the level of heparin-binding protein in patients with acute lung injury [PDF]

, 2013
Background: Heparin-binding protein is released by neutrophils during inflammation and disrupts the integrity of the alveolar and capillary endothelial barrier implicated in the development of acute lung injury and systemic organ failure.
A Linder, Cecilia M O’Kane, Daniel F McAuley, DF McAuley, DG Sinclair, G Weitz-Schmidt, H Herwald, H Sengelov, H Tapper, Heiko Herwald, J Grommes, JR Jacobson, K Tsushima, Karim Dib, KP Steinberg, M Shyamsundar, MB Fessler, MS Chew, MS Diamond, Murali Shyamsundar, N Gautam, O Soehnlein, O Soehnlein, S Steiner, S Zhang, Thelma R Craig, TR Craig, WM Shafer   +27 more
core   +1 more source

Variation in Psychotropic and Non‐Psychotropic Prescribing in Nursing Homes: A Multi‐Level EMR‐Based Retrospective Cohort Study

Journal of the American Geriatrics Society, Volume 74, Issue 4, Page 1099-1109, April 2026.
ABSTRACT Background Antipsychotic medications remain widely used in nursing homes (NHs) despite guidelines discouraging potentially inappropriate use. While home‐level variation is known, less is understood at the unit and organization levels, or across other psychotropic and non‐psychotropic drugs.
Darly Dash, Ahmad Rahim, Henry Yu‐Hin Siu, Aaron Jones, Maya Potter, Sophiya Benjamin, Paul R. Katz, Jeffrey W. Poss, George A. Heckman, Andrew P. Costa   +9 more
wiley   +1 more source

Comparative Efficacy of Initial Statin and Ezetimibe Combination versus Statin Monotherapy on Cardiovascular Outcomes in Diabetes Mellitus: A Nationwide Cohort Study [PDF]

Diabetes & Metabolism Journal
Background This study aimed to assess the efficacy of an initial combination therapy of statin and ezetimibe compared with statin monotherapy on major cardiovascular outcomes in individuals with diabetes.
Minji Sohn, Young-Hwan Park, Soo Lim
doaj   +1 more source

Current Advancements of Probiotic Foods and Their Role in Sustainable Food Security

Food Bioengineering, Volume 5, Issue 1, Page 105-123, March 2026.
ABSTRACT Probiotic foods have evolved from traditional fermented products to scientifically validated functional foods, defined by the FAO and WHO as live microorganism that confer a health benefit on the host when administered in adequate amounts, with effects being strain, does and end point specific.
Ashenafi Teklay Yaekob, Gebremedhin Gebreslassie, Etsay Mesele, Tesfakiros Semere   +3 more
wiley   +1 more source

Statin use in patients with hormone receptor‐positive metastatic breast cancer treated with everolimus and exemestane

Cancer Medicine, 2023
Background We analyzed the effect of statins in patients with hormone receptor‐positive (HR+) metastatic breast cancer treated with everolimus + exemestane (EverX).
Kyoungmin Lee, Eunjin Noh, Seok Joo Moon, Yoonjung Yoonie Joo, Eun Joo Kang, Jae Hong Seo, In Hae Park   +6 more
doaj   +1 more source

Spielen Statine eine Rolle als adjuvante Therapie bei Entzündung? / Do statins play a role as an adjuvant therapy in inflammation? [PDF]

, 2010
Despite recent advances in management of patients in intensive care units, sepsis and septic shock are the major causes of morbidity and mortality. Prompt and adequate antibiotic therapy accompanied by surgical removal of the infectious material are the ...
Almog, Annane, Annane, Barringer, Bengsch, Berbe, Bernard, Blankenhorn, Briegel, Casey, Chalmers, Chua, Cohen, Colli, Doig, Donnino, Downward, Endres, Esmon, Essig, Faggiotto, Farmer, Fernandez, Flegel, Foletta, Fraunberger, Frost, Fruscella, Goldstein, Goldstein, Guijarro, Gupta, Hackam, Hak, Hancock, Harris, Haslinger, Hernandez, Huhle, Indolfi, Jakobisiak, Janda, Joyce, Kawamata, Kitchens, Kruger, Kruger, Kwak, Laufs, Laufs, Liappis, Majumdar, Mason, Mitani, Mitteregger, Netea, Netea, Niwa, Oelschlager, Pahan, Rauchhaus, Read, Rikitake, Sacks, Samtleben, Schafer, Schlienger, Schmidt, Shyamsundar, Sparrow, Sukhova, Takata, Takemoto, Tetta, Thomsen, Tleyjeh, Van Aelst, Walli, Walter, Wassmann, Weinstock, Werdan, Yang, Zimmermann   +83 more
core   +1 more source

Navigating the cholesterol maze: Key insights on use of statins in neurodegenerative disorders

Neuroprotection, Volume 4, Issue 1, Page 30-47, March 2026.
The graphical abstract encapsulates the dual neuroprotective mechanisms of statins in neurodegenerative diseases, highlighting both cholesterol‐dependent and cholesterol‐independent pathways. By inhibiting 3‐hydroxy‐3‐methylglutaryl coenzyme A (HMG‐CoA) reductase, statins reduce cholesterol synthesis, leading to altered lipid raft structures that ...
Jun Han Kuan, Roshan S. Raghavan, Dawn Li Wei Koh, Wing Yeng Tan, Igor Iezhitsa, Renu Agarwal   +5 more
wiley   +1 more source

Statin practices for ASCVD Prevention: A Cross-Sectional Analysis of Guideline Adherence in a High-Risk Local Patient Population

Journal of the Pakistan Medical Association
Objectives: To investigate the current practices of statin prescription and use for primary and secondary prevention of atherosclerotic cardiovascular disease.
Rizwana Kitchlew, Haseeb Mukhtar, Mobeen Farooqi, Muhammad Tayyab Ijaz, Zainab Aslam   +4 more
doaj   +1 more source

Type I and type III collagen immunoexpression in rabbit skin biopsy samples treated with rosuvastatin gel and autologous platelet-rich plasma [PDF]

Acta Cirúrgica Brasileira
Purpose: To evaluate whether the joint use of autologous platelet-rich plasma (aPRP) and rosuvastatin (RSV) in biopsies of dermal wounds induced in rabbits results in an additive effect on the immunoexpression of collagens type I and III, optimizing the ...
Cristoffer da Silva Santana, Maria Rosa Santos Breda, Yuri Ferreira Vicentini, Sérgio Alexandre Alcantara dos Santos, Luis Antonio Justulin Jr, Anthony Cesar de Souza Castilho, Gisele Alborghetti Nai, Cecília Laposy Santarém   +7 more
doaj   +1 more source

An unexpected link between fatty acid synthase and cholesterol synthesis in proinflammatory macrophage activation [PDF]

, 2018
Different immune activation states require distinct metabolic features and activities in immune cells. For instance, inhibition of fatty acid synthase (FASN), which catalyzes the synthesis of long-chain fatty acids, prevents the proinflammatory response ...
Angiari, Stefano, Carroll, Richard G., Galván-Peña, Silvia, Koppe, Emma L., Modis, Louise K., O'Neill, Luke A., Sévin, Daniel C., Triantafilou, Kathy, Triantafilou, Martha, Zaslona, Zbigniew   +9 more
core   +2 more sources