Results 61 to 70 of about 762,287 (195)

Adjunctive Use of Locally Delivered Statins in Periodontal Therapy and Pre‐Implant Bone Regeneration: A Systematic Review and Meta‐Analysis

Clinical and Experimental Dental Research, Volume 12, Issue 2, April 2026.
ABSTRACT Objectives This systematic review and meta‐analysis aimed to evaluate the adjunctive beneficial effects of locally delivered statins on probing pocket depth (PPD), clinical attachment level (CAL), bleeding on probing (BoP), and radiographic bone outcomes in both periodontal therapy (Step 2 non‐surgical periodontal therapy and Step 3 ...
Koki Yoshida, Sofia Heller, Nur Mousa, Lovisa Olén, Farah Asa'ad   +4 more
wiley   +1 more source

Statin-Associated Muscle Adverse Events : Update for clinicians

Sultan Qaboos University Medical Journal, 2016
Statins are potent medications which reduce low-density lipoprotein cholesterol (LDL-C) levels. Their efficacy in cardiovascular risk reduction is well established and indications for their use are expanding.
Maha A. Al-Mohaissen, Martha J. Ignaszewski, Jiri Frohlich, Andrew P. Ignaszewski   +3 more
doaj   +1 more source

Pravastatin Corrects Endothelial Dysfunction in Ex Vivo Uterine Radial Arteries in Preeclampsia

Acta Physiologica, Volume 242, Issue 4, April 2026.
ABSTRACT Aim Endothelium‐dependent relaxation in isolated uterine radial arteries from normotensive (NT) and preeclamptic (PE) pregnancies, and the acute effects of pravastatin in the latter vessels were assessed. Pravastatin is hypothesized to alleviate endothelial dysfunction in PE via modulating aspects of NO and endothelium‐derived ...
Nathan M. Luque, Leo Leader, Sandra M. Lowe, Steven D. Horrowitz, Marianne Tare, Victoria Hinkley, Vladimir V. Matchkov, Maged M. Costantine, Irit Markus, Lu Liu, Shaun L. Sandow, Timothy V. Murphy   +11 more
wiley   +1 more source

Reduction of opioid and barbiturate use following initiation of rimegepant for migraine in the United States

Headache: The Journal of Head and Face Pain, Volume 66, Issue 4, Page 835-845, April 2026.
Abstract Objective The primary objective of this study was to evaluate opioid and barbiturate utilization before and after the first prescription of the calcitonin gene–related peptide receptor antagonist rimegepant in individuals with migraine. Background Although not recommended in migraine treatment guidelines, opioids and barbiturates are often ...
Noah Rosen, Aaron Jenkins, Karin Hygge Blakeman, Feng Dai, Lucy Abraham, Chelsea Leroue, Josh Brown   +6 more
wiley   +1 more source

Short-Term Therapy with High Dose Atorvastatin in Patients with Coronary Artery Disease Can Reduce Inflammatory Process [PDF]

Acta Medica Iranica, 2010
"nCoronary heart disease is the leading cause of death and disability in adults. The association between acute coronary syndrom (ACS) and elevated serum high sensitivity c-reactive protein (hsCRP) suggests that chronic inflammation of the coronary ...
Vida Nesar Hossein, Keivan Yosef Nejad, Fatemeh Abdollahian   +2 more
doaj   +2 more sources

HMG-CoA-reductase inhibitors and neuropathy:reports to the Netherlands Pharmacovigilance Centre

, 2006
The number of patients taking HMG-CoA-reductase inhibitors for hypercholesterolaemia is growing rapidly. Treatment with HMG-CoA-reductase inhibitors significantly reduces the risk of cardiovascular morbidity and mortality, but may rarely cause serious ...
de Langen, J J, van Puijenbroek, E P; id_orcid   +1 more
core   +2 more sources

Comparative Efficacy of Initial Statin and Ezetimibe Combination versus Statin Monotherapy on Cardiovascular Outcomes in Diabetes Mellitus: A Nationwide Cohort Study [PDF]

Diabetes & Metabolism Journal
Background This study aimed to assess the efficacy of an initial combination therapy of statin and ezetimibe compared with statin monotherapy on major cardiovascular outcomes in individuals with diabetes.
Minji Sohn, Young-Hwan Park, Soo Lim
doaj   +1 more source

Variation in Psychotropic and Non‐Psychotropic Prescribing in Nursing Homes: A Multi‐Level EMR‐Based Retrospective Cohort Study

Journal of the American Geriatrics Society, Volume 74, Issue 4, Page 1099-1109, April 2026.
ABSTRACT Background Antipsychotic medications remain widely used in nursing homes (NHs) despite guidelines discouraging potentially inappropriate use. While home‐level variation is known, less is understood at the unit and organization levels, or across other psychotropic and non‐psychotropic drugs.
Darly Dash, Ahmad Rahim, Henry Yu‐Hin Siu, Aaron Jones, Maya Potter, Sophiya Benjamin, Paul R. Katz, Jeffrey W. Poss, George A. Heckman, Andrew P. Costa   +9 more
wiley   +1 more source

Enhanced seed phytosterol accumulation through expression of a modified HMG-CoA reductase

, 2006
The regulation of phytosterol biosynthesis in seeds is of interest to biotechnologists because of the efficacy of dietary phytosterols in reducing blood cholesterol in humans.
Powers, S. J., Hey, S. J., Hawkins, N. D., Halford, N. G., Beale, M. H., Ward, J. L.   +5 more
core   +1 more source

Effects of oxidized low density lipoprotein, lipid mediators and statins on vascular cell interactions [PDF]

, 1999
The integrin heterodimer CD11b/CD18 (alpha M beta 2, Mac-1, CR3) expressed on monocytes or polymorphonuclear leukocytes (PMN) is a receptor for iC3b, fibrinogen, heparin, and for intercellular adhesion molecule (ICAM)-1 on endothelium, crucially ...
Erl, Wolfgang, Weber, Christian, Kim S. C. Weber, Weber, Kim S.C., Weber, Peter C., Wolfgang Erl, Peter C. Weber, Christian Weber   +7 more
core   +1 more source