Results 61 to 70 of about 13,154 (208)
Statins and selective inhibition of Rho kinase protect small conductance calcium-activated potassium channel function (KCa2.3) in cerebral arteries [PDF]
, 2012 Background: In rat middle cerebral and mesenteric arteries the KCa2.3 component of endothelium-dependent hyperpolarization (EDH) is lost following stimulation of thromboxane (TP) receptors, an effect that may contribute to the endothelial dysfunction ...
Alister J. McNeish +4 more
core +4 more sources
Clinical and Experimental Dental Research, Volume 12, Issue 2, April 2026.ABSTRACT Objectives This systematic review and meta‐analysis aimed to evaluate the adjunctive beneficial effects of locally delivered statins on probing pocket depth (PPD), clinical attachment level (CAL), bleeding on probing (BoP), and radiographic bone outcomes in both periodontal therapy (Step 2 non‐surgical periodontal therapy and Step 3 ...
Koki Yoshida +4 more
wiley +1 more source
Statins for primary and secondary prevention in the oldest old : an overview of the existing evidence [PDF]
, 2012 Hypercholesterolemia, although a modifiable risk factor for cardiovascular disease, is still one of the leading causes of death among older people in western countries.
Petrovic, Mirko +2 more
core +1 more source
Pravastatin Corrects Endothelial Dysfunction in Ex Vivo Uterine Radial Arteries in Preeclampsia
Acta Physiologica, Volume 242, Issue 4, April 2026.ABSTRACT Aim Endothelium‐dependent relaxation in isolated uterine radial arteries from normotensive (NT) and preeclamptic (PE) pregnancies, and the acute effects of pravastatin in the latter vessels were assessed. Pravastatin is hypothesized to alleviate endothelial dysfunction in PE via modulating aspects of NO and endothelium‐derived ...
Nathan M. Luque +11 more
wiley +1 more source
Uso de estatinas e o risco de Diabetes Mellitus tipo 2: Revisão Baseada na Evidência
Revista Brasileira de Medicina de Família e Comunidade, 2016 Objetivo: Determinar se existe relação entre o uso de estatinas e a incidência de Diabetes Melittus tipo 2 (DM2). Métodos: Foram realizadas pesquisas nas bases de dados National Guidelines Clearinghouse, Cochrane Lybrary, Trip database, PubMed e MedLine ...
Susana Silva, Nuno Monteiro
doaj +1 more source
Comparison of the Effects of Ezetimibe-Statin Combination Therapy on Major Adverse Cardiovascular Events in Patients with and without Diabetes: A Meta-Analysis [PDF]
Endocrinology and Metabolism, 2018 BackgroundEzetimibe-statin combination therapy has been found to reduce low density lipoprotein cholesterol levels and the risk of major adverse cardiovascular events (MACEs) in large trials.
Namki Hong +13 more
doaj +1 more source
Diagnosis of Statin-Induced Necrotizing Myopathy: Contribution of Anti-HMGCR Antibodies
Acta Médica Portuguesa, 2022 Over the last few years, several cases of statin-induced necrotizing myopathy have been described. This myopathy is characterized by the necrosis of muscle fibers and the presence of anti-3-hydroxy-3-methylglutaryl-coenzyme A reductase (anti-HMGCR ...
Cláudia Fidalgo +3 more
doaj +1 more source
Update on statin-mediated anti-inflammatory activities in atherosclerosis [PDF]
, 2018 Anti-inflammatory activities of statins in atherosclerosis have been well documented by both basic research and clinical studies. Statins have been introduced in the 1980s as 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitors to block cholesterol
Mach, François, Montecucco, Fabrizio
core
Headache: The Journal of Head and Face Pain, Volume 66, Issue 4, Page 835-845, April 2026.Abstract Objective The primary objective of this study was to evaluate opioid and barbiturate utilization before and after the first prescription of the calcitonin gene–related peptide receptor antagonist rimegepant in individuals with migraine. Background Although not recommended in migraine treatment guidelines, opioids and barbiturates are often ...
Noah Rosen +6 more
wiley +1 more source
Statin-Associated Muscle Adverse Events : Update for clinicians
Sultan Qaboos University Medical Journal, 2016 Statins are potent medications which reduce low-density lipoprotein cholesterol (LDL-C) levels. Their efficacy in cardiovascular risk reduction is well established and indications for their use are expanding.
Maha A. Al-Mohaissen +3 more
doaj +1 more source