Results 61 to 70 of about 24,284 (163)

Statin Exposure Is Not Associated with Reduced Prevalence of Colorectal Neoplasia in Patients with Inflammatory Bowel Disease

Gut and Liver, 2019
Background/Aims Statins have been postulated to lower the risk of colorectal neoplasia. No studies have examined any possible chemopreventive effect of statins in patients with inflammatory bowel disease (IBD) undergoing colorectal cancer (CRC ...
Shailja C. Shah, Jason Glass, Gennaro Giustino, Joren R. ten Hove, Daniel Castaneda, Joana Torres, Akash Kumar, Jordan Elman, Thomas A. Ullman, Steven H. Itzkowitz   +9 more
doaj   +1 more source

Role of Statin Drugs for Polycystic Ovary Syndrome

Journal of Family and Reproductive Health, 2017
Objective: To review the potential role and specific impact of statin drugs in women with PCOS. The evidence for this use of statins in PCOS is limited and still under further investigation.
Lisa Cassidy Vu, Edwina Joe, Julienne K Kirk   +2 more
doaj  

Evaluating early administration of the hydroxymethylglutaryl-CoA reductase inhibitor simvastatin in the prevention and treatment of delirium in critically ill ventilated patients: a randomised, placebo-controlled trial (MoDUS) [PDF]

, 2017
Background: Delirium in critically ill patients is associated with poor clinical outcomes. Neuroinflammation might be an important mechanism in the pathogenesis of delirium, and since simvastatin has anti-inflammatory properties it might reduce delirium.
Page, Valerie J., Casarin, Annalisa, Ely, E. Wesley, Zhao, Xiaobei Bei, McDowell, Cliona, Murphy, Lynn, McAuley, Danny F   +6 more
openaire   +1 more source

Lipid management in patients newly referred to a vascular surgery outpatient clinic

JVS-Vascular Insights
Objective: To evaluate the lipid management of patients with atherosclerotic vascular disease at the time of first outpatient vascular surgery consult to identify potential opportunities for improved dyslipidemia pharmacotherapy and monitoring.
Martina Vergouwen, BN, Ali Bayrouti, BN, RN, Halli Krzyzaniak, BSc, MD, Paul F. Petrasek, MD, FRCSC   +3 more
doaj   +1 more source

Additive Effects of Ezetimibe and Statins in Managing Elevated LDL-C: An Approach to Reducing Cardiovascular Risk [PDF]

Journal of Advanced Biomedical Sciences
Elevated low-density lipoprotein cholesterol (LDL-C) is a key modifiable risk factor for cardiovascular disease. While statins are the cornerstone of LDL-C-lowering therapy, their long-term use may result in dose-dependent adverse effects.
Narges Yaghoobi, Mojtaba Farjam, Babak Pezeshki   +2 more
doaj  

A novel human hepatic organic anion transporting polypeptide (OATP2). Identification of a liver-specific human organic anion transporting polypeptide and identification of rat and human hydroxymethylglutaryl-CoA reductase inhibitor transporters.

The Journal of biological chemistry, 2000
A novel human organic transporter, OATP2, has been identified that transports taurocholic acid, the adrenal androgen dehydroepiandrosterone sulfate, and thyroid hormone, as well as the hydroxymethylglutaryl-CoA reductase inhibitor, pravastatin. OATP2 is expressed exclusively in liver in contrast to all other known transporter subtypes that are found in
B, Hsiang, Y, Zhu, Z, Wang, Y, Wu, V, Sasseville, W P, Yang, T G, Kirchgessner   +6 more
openaire   +1 more source

Effect of Ischemic Postconditioning and Atorvastatin in the Prevention of Remote Lung Reperfusion Injury

Brazilian Journal of Cardiovascular Surgery
Objective: The aim of the present study was to evaluate the ability of ischemic postconditioning, atorvastatin and both associated to prevent or minimize reperfusion injury in the lung of rats subjected to ischemia and reperfusion by abdominal aortic ...
Carlos Henrique Marques dos Santos, Doroty Mesquita Dourado, Baldomero Antonio Kato da Silva, Henrique Budib Dorsa Pontes, Euler de Azevedo Neto, Giovanna Serra da Cruz Vendas, Ian de Oliveira Chaves, João Victor Cunha Miranda, João Victor Durães Gomes Oliva, Letícia do Espírito Santo Dias, Murillo Henrique Martins de Almeida, Trícia Luna Sampaio   +11 more
doaj   +1 more source

Switching to rosuvastatin plus ezetimibe in statin-treated stroke patients with low-density lipoprotein cholesterol levels above 70 mg/dL (SWITCH): a prospective observational study

Lipids in Health and Disease
Background Effective lipid management is critical for secondary stroke prevention, however, many patients fail to achieve target low-density lipoprotein cholesterol (LDL-C) levels with statin monotherapy. This study evaluated the real-world effectiveness
Wookjin Yang, Yeong-Bae Lee, Eung-Gyu Kim, Han-Jin Cho, Sungwook Yu, Joon-Tae Kim, Jong Wook Shin, Soo Joo Lee, Beom Joon Kim, Ji Man Hong, Seong-Ho Koh, Sang Joon An, A-Hyun Cho, Jin-Man Jung, Hyun-Ji Cho, Chulho Kim, Eung-Joon Lee, Jeong-Min Kim, Seung-Hoon Lee   +18 more
doaj   +1 more source

Atorvastatin-Associated Liver Injury: Outcome After Statin Rechallenge. [PDF]

Fundam Clin Pharmacol
Bertin B, Lacotte V, Cracowski JL, Gaiffe A, Dumortier J, Vial T.   +5 more
europepmc   +1 more source

Comments on 'Bisphosphonate and statin: adverse effects of co-medication on wound healing in in vitro models of periodontal tissues'. [PDF]

Acta Odontol Scand
Szaraz D, Perina V, Borilova Linhartova P.   +2 more
europepmc   +1 more source