Results 61 to 70 of about 21,088 (210)

Cloning of the Alcaligenes eutrophus genes for synthesis of poly-beta-hydroxybutyric acid (PHB) and synthesis of PHB in Escherichia coli [PDF]

, 1988
Eight mutants of Alcaligenes eutrophus defective in the intracellular accumulation of poly-beta-hydroxybutyric acid (PHB) were isolated after transposon Tn5 mutagenesis with the suicide vector pSUP5011.
A Steinbüchel, H G Schlegel, P Schubert
core   +2 more sources

Effect of Ceiling Fans on Core Temperature in Bed‐Resting Older Adults Exposed to Indoor Overheating

Journal of the American Geriatrics Society, Volume 74, Issue 1, Page 200-204, January 2026.
ABSTRACT Background Rising global temperatures have increased indoor overheating risks, posing significant health threats to vulnerable populations, particularly older adults. While electric fans are recommended for cooling at temperatures up to 40°C, the efficacy of ceiling fans in very warm indoor temperatures (~31°C) remains understudied.
Fergus K. O'Connor, Robert D. Meade, Kristina‐Marie T. Janetos, Caroline Li‐Maloney, Ronald J. Sigal, Pierre Boulay, Glen P. Kenny   +6 more
wiley   +1 more source

Avaliação de duas ORFs pertencentes ao cluster de produção de lovastatina em Aspergillus terreus [PDF]

, 2018
Dissertação (mestrado)—Universidade de Brasília, Departamento de Biologia Celular, Programa de Pós-Graduação em Biologia Molecular, 2018.Aspergillus terreus é um fungo filamentoso de importância biotecnológica por ser produtor de enzimas de interesse ...
Rodrigues, Kelly Assis
core   +1 more source

Risk Factors for Cardiovascular and Metabolic Disease: Integrating Traditional and Novel Paradigms

iNew Medicine, Volume 1, Issue 1, December 2025.
ABSTRACT Cardiovascular and metabolic diseases (CVMD), encompassing atherosclerotic cardiovascular disease (ASCVD), heart failure, obesity, type 2 diabetes mellitus (T2DM), and metabolic dysfunction‐associated steatotic liver disease (MASLD), remain the leading global cause of morbidity and mortality.
Zhihua Wang, Shuo Chen, Suowen Xu, Jianping Weng   +3 more
wiley   +1 more source

Integrated analysis of transcript-level regulation of metabolism reveals disease-relevant nodes of the human metabolic network [PDF]

, 2017
Metabolic diseases and comorbidities represent an ever-growing epidemic where multiple cell types impact tissue homeostasis. Here, the link between the metabolic and gene regulatory networks was studied through experimental and computational analysis ...
Berninger, Philipp, Galhardo, Mafalda, Heinäniemi, Merja, Lin, Jake, Sauter, Thomas, Sinkkonen, Lasse   +5 more
core  

Statin Use Is Associated With a Decline in Muscle Function and Mass Over Time, Irrespective of Statin Pharmacogenomic Score

Journal of Cachexia, Sarcopenia and Muscle, Volume 16, Issue 6, December 2025.
ABSTRACT Background Statins are cholesterol‐lowering drugs widely prescribed for preventing cardiovascular diseases. They may cause adverse effects on skeletal muscle, but it remains unclear whether they affect muscle function and mass. We aimed to evaluate the association between statin use and muscle function and mass, and whether the pharmacogenomic
Mélissa Gentreau, Mahitab Sakr, Salahuddin Mohammad, Ahmed M. Alsehli, Olga E. Titova, Gull Rukh, Helgi B. Schiöth   +6 more
wiley   +1 more source

Dual RNA-seq analysis provides new insights into interactions between Norway spruce and necrotrophic pathogen Heterobasidion annosum s.l. [PDF]

, 2019
BackgroundRoot and butt rot of conifer trees caused by fungi belonging to the Heterobasidion annosum species complex is one of the most economically important fungal diseases in commercial conifer plantations throughout the Northern hemisphere.
Asiegbu, Frederick Obioma, Ghimire, Rajendra P., Holopainen, Jarmo K., Julkunen-Tiitto, Riitta, Kasanen, Risto Aarne Olavi, Kivimäenpää, Minna, Kovalchuk, Andriy, Liu, Mengxia, Mukrimin, Mukrimin, Raffaello, Tommaso, Sun, Hui, Zeng, Zhen   +11 more
core   +5 more sources

Genetic variants linked to statin‐associated Type 2 diabetes mellitus: Findings from the UK Biobank and the All of Us Research Program

British Journal of Pharmacology, Volume 182, Issue 23, Page 5803-5813, December 2025.
Background and Purpose Statins are widely prescribed for the prevention of cardiovascular disease, yet recent studies suggest an increased risk of new‐onset Type 2 diabetes mellitus. This study aimed to identify genetic variants associated with statin‐associated new‐onset Type 2 diabetes mellitus from the UK Biobank and All of Us.
Yoon‐A Park, Da Hoon Lee, Jung Sun Kim, Jeong Yee, Hye Sun Gwak   +4 more
wiley   +1 more source

Uso crônico e regular de estatina previne fibrilação atrial no pós-operatório de cirurgia cardíaca Chronic and regular use of statin prevents atrial fibrillation in period after cardiac surgery

Arquivos Brasileiros de Cardiologia, 2010
FUNDAMENTO: Fibrilação atrial é uma complicação frequente no pós-operatório de cirurgia cardíaca. O uso prévio de estatinas pode reduzir a incidência dessa arritmia.
Renato Jorge Alves, Rodrigo Noronha Campos, Kenji Nakiri   +2 more
doaj  

A comprehensive update of the sequence and structure classification of kinases [PDF]

, 2005
BACKGROUND: A comprehensive update of the classification of all available kinases was carried out. This survey presents a complete global picture of this large functional class of proteins and confirms the soundness of our initial kinase classification ...
Cheek, Sara, Ginalski, Krzysztof, Grishin, Nick V, Zhang, Hong   +3 more
core   +3 more sources